Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Votoplam
Item number: TGM-T79865-50mg
Description: Votoplam functions as a gene splicing modulator, employed in the inhibition of Huntington's disease [1]. Target: DNA/RNA Synthesis
| CAS | 2407849-89-0 |
| MW: | 419.48 D |
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Ibuzatrelvir
Item number: TGM-T79867-50mg
Description: Ibuzatrelvir (PF-07817883) is an antiviral compound that inhibits the SARS-CoV-2 3CL protease, used in treating COVID-19 [1]. Target: Virus Protease
| Keywords: | PF-07817883 |
| Application: | Targets SARS coronavirus 3C-like proteinase [EC:3.4.22.69] (nsp5) |
| CAS | 2755812-39-4 |
| MW: | 489.49 D |
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Tirfipiravir
Item number: TGM-T79868-50mg
Description: Tirapiravir is an antiviral nucleoside analog that exhibits activity against both the novel coronavirus and influenza virus [1]. Target: Influenza Virus
| CAS | 2759996-93-3 |
| MW: | 355.3 D |
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RMC-4998
Item number: TGM-T79870-50mg
Description: RMC-4998 is a molecular glue compound with potent antitumor activity, forming a ternary complex with CYPA and an activated KRAS G12C mutation. Binding of CYPA to KRAS G12C hinders the interaction between activated KRAS mutants and downstream effector proteins, obstructing proliferative cell signaling...
| CAS | 2642037-07-6 |
| MW: | 983.25 D |
From 186.00€
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S6K2-IN-1
Item number: TGM-T79871-50mg
Description: S6K2-IN-1 (Compound 2) is an S6K2 inhibitor with an IC50 of 22 nM and displays inhibitory activity against FGFR4 with an IC50 of 216 nM, demonstrating acceptable stability in mouse liver microsomes [1]. Target: FGFR
| MW: | 561.95 D |
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m-Se3
Item number: TGM-T79872-50mg
Description: m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1]. Target: c-Myc
| CAS | 2829939-44-6 |
| MW: | 605.37 D |
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TNG-462
Item number: TGM-T79873-50mg
Description: TNG-462 (Compound 1143) is an orally active PRMT5 inhibitor under investigation for the treatment of MTAP-deficient and/or MTA-accumulating cancers [1]. Target: Histone Methyltransferase
| CAS | 2760483-96-1 |
| MW: | 520.69 D |
From 266.00€
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CHK-336
Item number: TGM-T79874-50mg
Description: CHK-336 (Example 1), an orally active LDHA inhibitor (IC50 <1 nM), suppresses lactate production in mouse hepatocytes and is applicable in hyperoxaluria research [1]. Target: Others
| CAS | 2743436-86-2 |
| MW: | 530.57 D |
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GDC-6599
Item number: TGM-T79875-50mg
Description: GDC-6599 (Example 8) is an orally active TRPA1 channel inhibitor, potentially useful for researching TRPA1-mediated conditions, including pain [1]. Target: Others
| CAS | 2376824-99-4 |
| MW: | 426.86 D |
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EDI048
Item number: TGM-T79876-50mg
Description: EDI048, also known as compound 1.16, is an orally active inhibitor of Cryptosporidium PI4K, utilized in the study of cryptosporidiosis [1]. Target: PI4K
| CAS | 2767264-57-1 |
| MW: | 476.91 D |
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MTvkPABC-P5
Item number: TGM-T79877-50mg
Description: MTvkPABC-P5d, functioning as a TLR7 agonist, serves as an immune stimulant and is utilized in the synthesis of immune-stimulating antibody conjugates (ISACs) [1]. Target: Others
| MW: | 1076.2 D |
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Hydroxy-PP-Me
Item number: TGM-T79878-1mg
Description: Hydroxy-PP-Me is a potent and specific CBR1 inhibitor with an IC50 of 759 nM. It inhibits serum-withdrawal-induced apoptosis and, when used in conjunction with As2O3, enhances As2O3-induced apoptotic cell death [1] [2]. Target: Apoptosis. Smiles: OC1=CC=CC(=C1)C2=CN(C=3N=CN=C(NC)C32)C(C)C
| CAS | 833481-77-9 |
| MW: | 282.34 D |
188.00€
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