Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Naratuximab
Item number: TGM-T81703-10mg
Description: Naratuximab emtansine [1] is a humanized monoclonal antibody (Anti-TSPAN26/CD37 Reference Antibody (naratuximab)) that specifically targets CD37 (TSPAN26) and serves as the basis for creating an antibody-drug conjugate (ADC) compound. Target: ADC Antibody
| Keywords: | Anti-TSPAN26/CD37 Reference Antibody (naratuximab) |
From 178.00€
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Naptumomab
Item number: TGM-T81704-10mg
Description: Naptumomab, a tumor-targeting superantigen (TTS), is a fusion protein that activates the immune system to recognize and eradicate tumor cells. It shows promise in researching refractory solid tumors, including renal cell carcinoma [1] [2].
From 233.00€
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Nagrestipen
Item number: TGM-T81708-50mg
Description: Nagrestipen, a variant of the human macrophage inflammatory protein-1 alpha (MIP-1alpha), also referred to as ECI 301, exhibits antitumor activity. It is employed in therapeutic trials focused on cancer, assessing its efficacy in the contexts of tumors, metastasis, radiation oncology, and the analysis...
| Application: | Hematopoietic inhibitor |
| CAS | 166089-33-4 |
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N-4'-(p-Trifluoromethylphenyl)butyl-DAB
Item number: TGM-T81713-50mg
Description: N-4'-(p-Trifluoromethylphenyl)butyl-DAB (compound 5g) acts as an agonist for lysosomal acid alpha-glucosidase (GAA), dose-dependently enhancing intracellular GAA activities in Pompe disease patient fibroblasts harboring the M519V mutation [1]. Target: Others
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N3-PEG8-Phe-Lys-PABC-Gefitinib
Item number: TGM-T81714-50mg
Description: N3-PEG8-Phe-Lys-PABC-Gefitinib is an antibody-drug conjugate (ADC) agent-linker complex exhibiting potent antitumor activity. It incorporates the orally active EGFR tyrosine kinase inhibitor Gefitinib, tethered by the cleavable linker N3-PEG8-Phe-Lys-PABC. As a click chemistry reagent, it features an...
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N36 peptide
Item number: TGM-T81716-50mg
Description: N36 peptide, an (HIV-1 gp41 fusion peptide), exhibits biological activity.
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Mz325
Item number: TGM-T81725-50mg
Description: Mz325 serves as a dual inhibitor of both HDAC and Sirt2, exhibiting an IC50 of 9.7 µM against Sirt2, which are implicated in the pathogenesis of cancer and neurodegenerative diseases [1]. Target: HDAC
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Myristoyl-(Lys12,27,28)-VIP-Gly-Gly-Thr free acid
Item number: TGM-T81727-100mg
Description: Myristoyl-(Lys12,27,28)-VIP-Gly-Gly-Thr (free acid) acts as a selective and potent antagonist of the VPAC2 receptor [1].
| CAS | 2243219-86-3 |
From 248.00€
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Muzastotug
Item number: TGM-T81736-10mg
Description: Muzastotug is a humanized IgG1-kappa monoclonal antibody targeting CTLA4, functioning as an immunostimulant and antineoplastic [1]. Target: Others
From 156.00€
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Multi-target kinase inhibitor 2
Item number: TGM-T81739-50mg
Description: Compound 5K (Multi-target kinase inhibitor 2) is a multi-targeted kinase inhibitor demonstrating activity against EGFR, Her2, VEGFR2, and CDK2 with IC50 values between 40 to 204 nM. It exhibits cytotoxic effects on HepG2, HeLa, MDA-MB-231, and MCF-7 cell lines, with IC50 values of 41, 57, 51, and 59 µM,...
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Multi-kinase-IN-6
Item number: TGM-T81740-50mg
Description: Multi-kinase-IN-6 (compound 10e) is a multikinase inhibitor that impedes the activity of TrkA, ALK2, c-KIT, EGFR, PIM1, CK2alpha, CHK1, and CDK2. It exhibits antiproliferative effects on MCF7, HCT116, and EKVX cancer cell lines with IC50s of 3.36 µM, 1.40 µM, and 3.49 µM, respectively. Additionally,...
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mTOR inhibitor-14
Item number: TGM-T81744-50mg
Description: mTOR Inhibitor-14 (compound 14c) is a potent inhibitor of mTOR with minimal inhibition of CYP2C8 and has demonstrated the capability to inhibit tumor growth [1]. Target: mTOR
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