Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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SFNGGP-NH2
Item number: TGM-T80234-50mg
Description: SFNGGP-NH2 is a biologically active peptide that interacts with Protease-Activated Receptor 3 (PAR-3), a high-affinity thrombin receptor. Human cutaneous mast cells express PAR-3 mRNA, implicating a role in itch mechanotransduction, with both histamine-dependent and independent pathways reported. While...
| CAS | 261521-21-5 |
| MW: | 576.6 D |
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YFLLRNP
Item number: TGM-T80235-50mg
Description: YFLLRNP is a biologically active peptide functioning as a partial agonist of PAR-1, selectively activating the G12/13 signaling pathway. At low concentrations, YFLLRNP (60 µM) does not activate Gq or Gi pathways.
| CAS | 149440-16-4 |
| MW: | 922.08 D |
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TFLLRN-NH2
Item number: TGM-T80236-50mg
Description: TFLLRN-NH2 is a biologically active peptide functioning as a PAR-1 agonist.
| CAS | 244095-36-1 |
| MW: | 761.91 D |
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NODAGA-LM3
Item number: TGM-T80237-50mg
Description: NODAGA-LM3, when labeled with ^68Ga, serves as a PET imaging agent. As an SSTR2 antagonist, ^68Ga-NODAGA-LM3 is utilized for the visualization of SSTR-positive paragangliomas [1] [2].
| CAS | 1415238-78-6 |
| MW: | 1521.11 D |
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TFLLRNPNDK-NH2
Item number: TGM-T80239-50mg
Description: TFLLRNPNDK-NH2 is a biologically active peptide and a thrombin receptor activating peptide (TRAP). As a PAR-1 agonist, it reversibly binds to PAR-1, mimicking the 'tethered ligand' created by thrombin through proteolytic substrate cleavage. It also induces increased liquid and protein permeability,...
| CAS | 145229-90-9 |
| MW: | 1216.39 D |
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Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
Item number: TGM-T80240-50mg
Description: Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biologically active peptide functioning as a selective agonist for Protease Activated Receptor 1 (PAR-1) [a subtype of G-protein coupled receptors involved in mediating thrombin's cellular effects]. Exhibiting high specificity for PAR-1 over PAR-2, its...
| CAS | 211190-38-4 |
| MW: | 883.02 D |
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Calpastatin subdomain B
Item number: TGM-T80241-50mg
Description: Calpastatin subdomain B is a bioactive peptide that inhibits calpain activity. Target: Proteasome
| CAS | 128578-18-7 |
| MW: | 3136.57 D |
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TNO211
Item number: TGM-T80242-50mg
Description: TNO211 is a bioactive peptide that functions as a highly soluble fluorogenic substrate for select Matrix Metalloproteinases (MMPs)-specifically MMP-2, 8, 12, 13, and 14. Incorporating a cleavable Gly-Leu bond and an EDANS/DABCYL fluorophore/quencher pair, TNO211 enables sensitive detection of MMP...
| CAS | 193475-71-7 |
| MW: | 1325.54 D |
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gp91 ds-tat
Item number: TGM-T80243-1mg
Description: Gp91phox ds-tat, a biologically active peptide, functions as an inhibitor of NADPH oxidase assembly.
| MW: | 2452.94 D |
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Renin inhibitor peptide,rat
Item number: TGM-T80244-50mg
Description: Renin Inhibitor Peptide, Rat, is a biologically active peptide that functions as a specific inhibitor of rat renin.
| CAS | 115290-00-1 |
| MW: | 957.17 D |
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LL-37(17-32)
Item number: TGM-T80245-50mg
Description: LL-37(17-32) is a biologically active peptide fragment derived from the C-terminal domain of human cathelicidin antimicrobial peptide. This segment reverses ABCG2-mediated multidrug resistance in cancer cell lines, highlighting its potential therapeutic role against drug resistance.
| CAS | 717919-61-4 |
| MW: | 2045.48 D |
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TAT-GluR23A Fusion Peptide
Item number: TGM-T80246-50mg
Description: TAT-GluR23A Fusion Peptide is a bioactive peptide comprising the GluR23A sequence-residues 869 to 877 of GluR23Y with alanine replacing tyrosine-and an 11 amino acid cell-permeable HIV Trans-Activator of Transcription (TAT) protein transduction domain (PTD). It serves as an inactive control counterpart...
| MW: | 2357.68 D |
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