Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Koshidacin B
Item number: TGM-T75536-50mg
Description: Koshidacin B, a cyclic tetrapeptide, exhibits potent antiplasmodial activity, evidenced by its ability to inhibit Plasmodium falciparum strains FCR3 and K1 with IC50 values of 0.89 µM and 0.83 µM, respectively. It has been shown to effectively suppress malaria parasites in vivo and has potential...
| CAS | 2925302-01-6 |
| MW: | 544.64 D |
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N-Acetyldopamine dimer-2
Item number: TGM-T75537-50mg
Description: N-Acetyldopamine dimer-2 (compound 2), an N-acetyldopamine dimer derived from the yellow powder of Periostracum Cicadae, exhibits antioxidant and anti-inflammatory properties by inhibiting oxidized low-density lipoprotein (LDL) oxidation, reducing reactive oxygen species (ROS) generation and nitric...
| CAS | 916888-49-8 |
| MW: | 384.38 D |
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Alismanol M
Item number: TGM-T75538-50mg
Description: Alismanol M, a protostane-type triterpenoid isolated from the rhizome of Alisma orientale, functions as a farnesoid X receptor (FXR) agonist with an EC50 value of 50.25 µM. It is utilized in researching cholestasis and nonalcoholic steatohepatitis [1]. Target: Others
| CAS | 2408810-59-1 |
| MW: | 504.7 D |
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Nereistoxin
Item number: TGM-T75539-50mg
Description: Nereistoxin (Nereistoxine), a neurotoxin derived from Lumbriconereis heteropoda, a marine annelid, functions by inhibiting nicotinic acetylcholine receptors [1]. Target: Others
| CAS | 1631-58-9 |
| MW: | 149.28 D |
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Tanshinone IIA anhydride
Item number: TGM-T75541-50mg
Description: Tanshinone IIA anhydride is a potent, irreversible inhibitor of human carboxylesterase (CE), exhibiting inhibitory constants (K i values) of 1.9 nM for human CE1 and 1.4 nM for human intestinal CE (hiCE), respectively [1]. Target: Others
| CAS | 61077-78-9 |
| MW: | 310.34 D |
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Celangulatin C
Item number: TGM-T75542-50mg
Description: Celangulatin C, an insecticidal sesquiterpene polyol ester isolated from the root bark of Pseudolarix kaempferi, exhibits an LD50 of 280.4 µg/mL against Mythimna separata [1] [2]. Target: Others
| CAS | 1000784-44-0 |
| MW: | 634.67 D |
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Angulatin G
Item number: TGM-T75543-50mg
Description: Angulatin G (Celangulatin E), an insecticidal sesquiterpene polyol ester featuring a beta-dihydroagarofuran sesquiterpene skeleton, is derived from the root bark of Celastrus angulatus. It demonstrates an LD50 of 1656.4 µg/mL against Mythimna separata [1]. Target: Others
| CAS | 1000784-46-2 |
| MW: | 666.67 D |
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AChE/BChE-IN-11
Item number: TGM-T75544-50mg
Description: AChE/BChE-IN-11 (compound 1), a natural product derived from artichoke leaves, is a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values of 70 µM and 71 µM, respectively. This compound is used in Alzheimer's disease (AD) research [1]. Target: Others
| CAS | 80443-12-5 |
| MW: | 466.39 D |
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PCSK9-IN-9
Item number: TGM-T75545-50mg
Description: PCSK9-IN-9, a natural isocoumarin, inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9), IDOL, and SREBP2 mRNA expression, demonstrating specificity by inhibiting PCSK9 with an IC50 value of 11.9 µM [1]. Target: Others
| MW: | 412.56 D |
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Ellagic acid 4-O-beta-D-xylopyranoside
Item number: TGM-T75546-50mg
Description: Ellagic acid 4-O-beta-D-xylopyranoside, a naturally occurring ellagitannin, exhibits antimicrobial properties and inhibits xanthine oxidase with an IC50 value of 2.1 µg/mL [1]. Target: Others
| CAS | 139163-18-1 |
| MW: | 434.31 D |
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Maritimetin
Item number: TGM-T75547-50mg
Description: Maritimein, an aurone isolated from Coreopsis tinctoria, exhibits significant diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity, with an IC50 value of 4.12 µM. It is utilized in cardiovascular disease research [1]. Target: Others
| CAS | 576-02-3 |
| MW: | 286.24 D |
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Hyp9
Item number: TGM-T75550-50mg
Description: Hyp9, a specific agonist for the transient receptor potential canonical 6 (TRPC6) channel, is utilized in spinal cord injury (SCI) research [1]. Target: Others
| CAS | 3118-34-1 |
| MW: | 322.4 D |
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