Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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11569 from 12257 pages
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5-HT2A receptor agonist-3
5-HT2A receptor agonist-3

Item number: TGM-T79155-50mg

Description: 5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM. It also demonstrates a remarkable 124-fold selectivity over its structurally analogous 5-HT2C receptor [1]. Target: 5-HT Receptor
CAS 1391499-52-7
MW: 420.34 D
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(R)-SKBG-1
(R)-SKBG-1

Item number: TGM-T79156-5mg

Description: (R)-SKBG-1 is an inhibitor of the RNA-binding protein NONO, effectively downregulating androgen receptor expression by targeting both AR-FL mRNA and AR-V7 mRNA, with inhibition concentration (IC50) values of 3.1 µM and 5.5 µM, respectively [1]. Target: Androgen Receptor
144.00€ *
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PROTAC PTPN2 degrader-2
PROTAC PTPN2 degrader-2

Item number: TGM-T79160-50mg

Description: PROTAC PTPN2 degrader-2 (example 187B) is a potent PTPN2-degrading agent with potential applications in cancer and metabolic disease research [1]. Target: Phosphatase
CAS 2912307-38-9
MW: 997.53 D
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PROTAC PTPN2 degrader-2 TFA
PROTAC PTPN2 degrader-2 TFA

Item number: TGM-T79161-50mg

Description: PROTAC PTPN2 degrader-2 (example 187B) TFA is a potent Protein Tyrosine Phosphatase Non-receptor Type 2 (PTPN2) degrader with potential applications in cancer and metabolic disease research [1]. Target: Phosphatase
CAS 2912307-39-0
MW: 1111.55 D
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SOS1/KRAS-IN-1
SOS1/KRAS-IN-1

Item number: TGM-T79162-100mg

Description: SOS1/KRAS-IN-1 (Compound 2) serves as an inhibitor of SOS1/KRAS, with potential application in the study of diseases mediated by SOS1/KRAS [1]. Target: Ras
CAS 2836330-34-6
MW: 457.49 D
From 1,867.00€ *
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RET-IN-24
RET-IN-24

Item number: TGM-T79163-100mg

Description: RET-IN-24 (Compound 26) is a selective RET tyrosine kinase inhibitor with demonstrated antitumor activity [1]. Target: Others
CAS 2583767-68-2
MW: 516.55 D
From 1,298.00€ *
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USP7-IN-12
USP7-IN-12

Item number: TGM-T79164-50mg

Description: USP7-IN-12 (compound 1) is a potent, orally active Usp7 inhibitor with an IC50 of 3.67 nM, demonstrating antiproliferative activity [1]. Target: Others
CAS 2763698-01-5
MW: 551.07 D
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DNA-PK-IN-10
DNA-PK-IN-10

Item number: TGM-T79165-50mg

Description: DNA-PK-IN-10 is a DNA-PK inhibitor used in breast cancer and non-small cell lung cancer research [1]. Target: DNA-PK
CAS 2919315-89-0
MW: 444.53 D
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KRAS G12C inhibitor 60
KRAS G12C inhibitor 60

Item number: TGM-T79166-50mg

Description: KRAS G12C Inhibitor 60 (compound 23), a selective inhibitor targeting the Kras-G12C mutation, is utilized in the investigation of lung, colorectal, and pancreatic cancers [1]. Target: Ras
MW: 627.61 D
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CBP-IN-1
CBP-IN-1

Item number: TGM-T79168-100mg

Description: CBP-IN-1 (compound 12) is a potent CBP inhibitor with an IC50 of 1.5 nM, additionally suppressing CBP BRET and BRD4(1) with IC50 values of 690 nM and 3100 nM, respectively [1]. Target: Epigenetic Reader Domain
CAS 1936431-44-5
MW: 509.59 D
From 1,298.00€ *
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CDK7-IN-22
CDK7-IN-22

Item number: TGM-T79169-100mg

Description: CDK7-IN-22 (compound 101) is a selective CDK7 inhibitor with demonstrated antitumor activity and specificity for CDK7 [1]. Target: CDK
CAS 2173190-60-6
MW: 430.47 D
From 1,725.00€ *
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Immuno modulator-1
Immuno modulator-1

Item number: TGM-T79170-50mg

Description: Immuno modulator-1 (compound 22) effectively suppresses the secretion of TNFalpha and IL-2 in human peripheral blood mononuclear cells (hPBMC), with IC50 values of 4.7 nM and 26 nM, respectively, and exhibits a 20% inhibitory effect on the hERG potassium channel at a concentration of 3 µM [1]. Target:...
CAS 2757469-20-6
MW: 582.62 D
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Review
11569 from 12257 pages