Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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GIP/GLP-1 dual receptor agonist-1
Item number: TGM-T75150-50mg
Description: GIP/GLP-1 dual receptor agonist-1 (compound 4), a receptor agonist for both GIP and GLP-1, shows potential for researching metabolic disorders and fatty liver diseases, such as nonalcoholic steatohepatitis (NASH) and nonalcoholic fatty liver disease (NAFLD) [1]. Target: Others
| CAS | 2807481-02-1 |
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ARC19499
Item number: TGM-T75152-50mg
Description: ARC19499, an aptamer, inhibits the tissue factor pathway inhibitor (TFPI), facilitating clot initiation and propagation through the extrinsic pathway. It binds specifically to TFPI, blocking its inhibition of both factor Xa and the TF/factor VIIa complex, thereby correcting thrombin generation in...
| CAS | 1350667-54-7 |
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ATU027
Item number: TGM-T75154-50mg
Description: ATU027, a small interfering RNA (siRNA), silences protein kinase N3 (PKN3) expression in the vascular endothelium. It has been demonstrated to thwart local tumor invasion, as well as lymph node and pulmonary metastasis, in mouse cancer models. Target: Others
| CAS | 1415935-22-6 |
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Bamosiran
Item number: TGM-T75155-50mg
Description: Bamosiran, a small interfering RNA (siRNA), specifically targets the beta-adrenergic receptor 2 to reduce intraocular pressure. Target: Others
| CAS | 1337968-84-9 |
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Bevasiranib
Item number: TGM-T75156-50mg
Description: Bevasiranib, a siRNA, is specifically engineered to suppress the expression of genes responsible for the production of vascular endothelial growth factor (VEGF), a critical factor in the development of choroidal neo-vascularization (CNV), which precedes wet age-related macular degeneration (wet AMD)....
| CAS | 959961-96-7 |
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SARS-CoV-2-IN-47
Item number: TGM-T78719-50mg
Description: SARS-CoV-2-IN-47 (Compound 13), with IC50 values of 0.77 µM against Omicron BA.1 and 0.93 µM against the Delta strain, acts as an inhibitor of SARS-CoV-2 and is used in antiviral research [1]. Target: SARS-CoV
| MW: | 527.65 D |
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SARS-CoV-2-IN-48
Item number: TGM-T78720-50mg
Description: SARS-CoV-2-IN-48 (compound 19) is an inhibitor of SARS-CoV-2, with an IC50 of 2.7 µM against the Omicron BA.1 variant and demonstrating antiviral activities [1]. Target: SARS-CoV
| MW: | 463.48 D |
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ZINC475239213
Item number: TGM-T78722-100mg
Description: ZINC475239213 acts as an inhibitor targeting the SARS-CoV-2 Nsp14 N7-Methyltransferase with an IC50 value of 20 µM [1]. Target: SARS-CoV
| CAS | 2871002-89-8 |
| MW: | 369.38 D |
From 1,440.00€
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ZINC61142882
Item number: TGM-T78723-50mg
Description: ZINC61142882 is a SARS-CoV-2 Nsp14 N7-Methyltransferase inhibitor with an IC50 value of 6 µM [1]. Target: SARS-CoV
| MW: | 387.19 D |
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Acryl42-10
Item number: TGM-T78724-50mg
Description: Acryl42-10 serves as a covalent inhibitor for the SARS-CoV-2 Nsp14 N7-Methyltransferase, exhibiting an inhibition concentration (IC50) of 7 µM [1]. Target: SARS-CoV
| MW: | 405.88 D |
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SARS-CoV-2 nsp14-IN-3
Item number: TGM-T78725-100mg
Description: SARS-CoV-2 nsp14-IN-3 (4975) is a potent inhibitor of the N7-Methyltransferase activity of SARS-CoV-2 nonstructural protein 14 (Nsp14), with an IC50 value of 3.5 µM [1]. Target: SARS-CoV
| CAS | 2920574-16-7 |
| MW: | 343.4 D |
From 1,440.00€
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Z795161988
Item number: TGM-T78726-50mg
Description: Z795161988 functions as an inhibitor targeting the SARS-CoV-2 Nsp14 N7-Methyltransferase, exhibiting an inhibitory concentration (IC50) of 2.2 µM [1]. Target: SARS-CoV
| MW: | 390.19 D |
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