Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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BTK-IN-24
Item number: TGM-T75124-10mg
Description: BTK-IN-24 (compound 195) is a potent BTK inhibitor via a ubiquitin proteolytic pathway [1] . Target: Others
| CAS | 2649400-34-8 |
| MW: | 806.96 D |
From 357.00€
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I-152
Item number: TGM-T75128-50mg
Description: I-152, a conjugate of N-acetyl-cysteine (NAC) and cysteamine (MEA), activates NRF2 and ATF4 signaling pathways and exhibits anti-proliferative properties [1]. Target: Others
| CAS | 311343-11-0 |
| MW: | 264.36 D |
From 198.00€
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Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br
Item number: TGM-T75130-50mg
Description: Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Br is a drug-linker conjugate for antibody-drug conjugates (ADCs), serving as a reaction reagent in the creation of anti-CD40 antibody agent conjugates [1]. Target: Drug-Linker Conjugates for ADC, Others
| CAS | 2345733-40-4 |
| MW: | 948.74 D |
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NRX-0492
Item number: TGM-T75133-50mg
Description: NRX-0492 is an orally administered compound that efficiently degrades Bruton's tyrosine kinase (BTK) by catalyzing its ubiquitylation and subsequent proteasomal degradation, achieving half-maximal degradation concentrations (DC50) of =0.2 nM and 90% degradation concentrations (DC90) of =0.5 nM....
| CAS | 2416130-57-7 |
| MW: | 817.94 D |
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MC-GGFG-AM-(10Me-11F-Camptothecin)
Item number: TGM-T75134-50mg
Description: MC-GGFG-AM-(10Me-11F-Camptothecin) serves as a linker-payload conjugate in the synthesis of ZW251, an antibody-drug conjugate (ADC) targeting human GPC3. ZW251 comprises a humanized IgG1 antibody linked to ZD06519, a novel camptothecin-based topoisomerase 1 inhibitor, through a maleimide-anchor and a...
| CAS | 2873460-70-7 |
| MW: | 1038.04 D |
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FHD-609
Item number: TGM-T75135-50mg
Description: FHD-609, an inhibitor and degrader of BRD9 (bromodomain-containing protein 9), targets the ncBAF complex and is useful for researching a broad spectrum of cancers with mutations in a BAF complex subunit. When used alongside Telomelysin or INO5401, FHD-609 could be effective in treating adrenocortical...
| CAS | 2676211-64-4 |
| MW: | 829 D |
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IRAK degrader-1
Item number: TGM-T75136-5mg
Description: IRAK degrader-1 (example I-3) is a potent IRAK degrader [1]. Target: Others
| CAS | 2655656-99-6 |
| MW: | 871.97 D |
266.00€
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Lipid 14
Item number: TGM-T75138-2mg
Description: Lipid 14, a potent ionizable compound, is essential for synthesizing lipid nanoparticles (LNPs) [1]. Target: Others
| CAS | 2430034-05-0 |
| MW: | 907.48 D |
233.00€
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TMX1
Item number: TGM-T75139-50mg
Description: TMX1 is a molecular glue degrader that covalently targets BRD4. It selectively recruits DCAF16 to the BRD4 BD2 domain, leading to the degradation of BRD4 [1]. Target: Others
| MW: | 476.59 D |
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CPD-1224
Item number: TGM-T75140-50mg
Description: CPD-1224, an orally active derivative that binds cereblon ligands to ALK inhibitors, specifically targets and degrades EML4-ALK oncogenic fusions, including ALK and its mutants L1196M/G1202R. Target: Others
| CAS | 2891620-68-9 |
| MW: | 855.4 D |
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Mcl-1 inhibitor 12
Item number: TGM-T75143-50mg
Description: Mcl-1 Inhibitor 12 (Example 10), with a K i of 0.22 nM, functions as an MCL-1 inhibitor. It is utilized in cancer research [1]. Target: Others
| Application: | Mcl-1 inhibitor |
| CAS | 2445466-24-8 |
| MW: | 858.35 D |
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TRV-7019
Item number: TGM-T75145-2mg
Description: TRV-7019 is a butyrylcholinesterase-targeting radioligand capable of penetrating the blood-brain barrier (BBB) for brain imaging. It is utilized for diagnosing conditions such as amyloid diseases, multiple sclerosis, brain tumors, or to assess butyrylcholinesterase activity [1]. Target: Others
| CAS | 2598164-15-7 |
| MW: | 369.15 D |
61.00€
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