Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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11564 from 12310 pages
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Chitin synthase inhibitor 1
Chitin synthase inhibitor 1

Item number: TGM-T62068-100mg

Description: Chitin synthase inhibitor 1 is a potent and selective chitin synthase (CHS) inhibitor with an IC50 of 0.12 mM, effectively inhibiting drug-resistant fungi variants. Target: Others
MW: 409.87 D
From 1,440.00€ *
Review
Chitinase-IN-4
Chitinase-IN-4

Item number: TGM-T62069-100mg

Description: Chitinase-IN-4 (compound 8f) is a potent and selective inhibitor of OfChi-h with an IC50 value of 0.1 µM, exhibiting strong insecticidal activity. Target: Others
MW: 409.92 D
From 1,440.00€ *
Review
VEGFR-2-IN-16
VEGFR-2-IN-16

Item number: TGM-T62071-100mg

Description: VEGFR-2-IN-16 (Compound 15b) is a potent VEGFR-2 inhibitor with an IC50 of 86.36 nM, demonstrating significant antitumor effects. Target: Others
MW: 410.25 D
From 1,440.00€ *
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HDAC-IN-47
HDAC-IN-47

Item number: TGM-T62072-100mg

Description: HDAC-IN-47 is an orally active histone deacetylase (HDAC) inhibitor, with IC50 values of 19.75 nM, 57.8 nM, 40.27 nM, 5.63 nM, and 302.73 nM for HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8, respectively. HDAC-IN-47 can block the cell cycle in the G2/M phase, inhibit autophagy, induce apoptosis via the...
MW: 410.26 D
From 1,440.00€ *
Review
MYF-03-176
MYF-03-176

Item number: TGM-T62074-100mg

Description: MYF-03-176, an orally active anticancer agent, exhibits strong antitumor effects in the MPM mouse xenograft tumor model following oral administration. Target: Others
MW: 410.37 D
From 1,080.00€ *
Review
LPM4870108
LPM4870108

Item number: TGM-T62076-100mg

Description: LPM4870108 is a potent, orally active pan-Trk (WT/MT) inhibitor that acts on TrkC (IC50: 0.2 nM), TrkA (IC50: 2.4 nM), TrkAG595R (IC50: 3.5 nM) and TrkAG667C (IC50: 2.3 nM), and is more selective for Trk than ALK (IC50: 2.3 nM). LPM4870108 showed anti-tumour effects. Target: Others
MW: 410.4 D
From 1,440.00€ *
Review
Akt/NF-kappaB/JNK-IN-1
Akt/NF-kappaB/JNK-IN-1

Item number: TGM-T62078-100mg

Description: Akt/NF-kappaB/JNK-IN-1 (Compound 2i) is an inhibitor of the Akt, NF-kappaB, and JNK signaling pathways, demonstrating inhibition of nitric oxide production (IC50: 3.15 µM) and exhibiting anti-inflammatory effects. Target: Others
MW: 410.42 D
From 1,440.00€ *
Review
Tuberculosis inhibitor 5
Tuberculosis inhibitor 5

Item number: TGM-T62086-100mg

Description: Tuberculosis inhibitor 5 (Compound 11i) is a potent antimycobacterial biphenyl analogue and anti-tuberculosis agent with no apparent cytotoxicity. Target: Others
MW: 410.49 D
From 1,440.00€ *
Review
Tuberculosis inhibitor 4
Tuberculosis inhibitor 4

Item number: TGM-T62087-100mg

Description: Tuberculosis inhibitor 4 (compound 16) is a spirothiazolidinone derived from mandelic acid, exhibiting potent antimycobacterial activity by inhibiting 98% of Mycobacterium tuberculosis strain H37Rv at concentrations below 6 µg/mL. Target: Others
MW: 410.53 D
From 1,440.00€ *
Review
FWM-1
FWM-1

Item number: TGM-T62089-100mg

Description: FWM-1 is a potent inhibitor of SARS-COV-2 NSP13 resolvase (free energy of binding: -328.6 kcal/mol).FWM-1 shows effective disruption of the binding of ATP to SARS-COV2 resolvase. Target: Others
MW: 410.86 D
From 1,440.00€ *
Review
TRK-IN-19
TRK-IN-19

Item number: TGM-T62095-100mg

Description: TRK-IN-19 (Compound I-10) is a potent TRK inhibitor with IC50 values of 1.1 nM for TRKA and 5.3 nM for TRKAG595R, demonstrating potential research value in cancer disease. Target: Others
MW: 411.47 D
From 1,440.00€ *
Review
Dyrk1A/alpha-synuclein-IN-1
Dyrk1A/alpha-synuclein-IN-1

Item number: TGM-T62096-100mg

Description: Dyrk1A/alpha-synuclein-IN-1 (Compound b1) is a dual inhibitor of Dyrk1A (IC50: 177 nM) and alpha-synuclein aggregation (IC50: 10.5 µM), characterized by CNS permeability and neuroprotective activity. Target: Others
MW: 411.48 D
From 1,440.00€ *
Review
11564 from 12310 pages