Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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alpha1A-AR Degrader 9c
Item number: TGM-T74557-5mg
Description: alpha1A-AR Degrader 9c is a potent, selective, and reversible PROTAC degrader targeting the alpha1A adrenergic receptor (alpha1A-AR) with a DC50 of 2.86 µM. It promotes the proteasomal degradation of the alpha1A-AR and exhibits anti-proliferative effects against PC-3 cells, presenting an IC50 value of...
| CAS | 2863635-02-1 |
| MW: | 829.82 D |
1,279.00€
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PROTAC_ERRalpha
Item number: TGM-T74559-50mg
Description: PROTAC_ERRalpha is a potent, selective degrader of ERRalpha, efficiently facilitating its proteasomal degradation. This compound specifically targets ERRalpha protein, achieving a degradation efficiency of over 80% [1]. Target: Others
| CAS | 1801547-15-8 |
| MW: | 949.03 D |
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PROTAC TYK2 degradation agent1
Item number: TGM-T75026-50mg
Description: PROTAC TYK2 Degradation Agent1 is a potent, subtype-selective degrader of TYK2, exhibiting degradation activity with a DC50 of 14 nM. It is utilized in autoimmune disease research [1]. Target: PROTACs
| CAS | 2921556-14-9 |
| MW: | 1056.28 D |
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G0-C14
Item number: TGM-T75027-100mg
Description: G0-C14, an alkyl-modified polyamidoamine (PAMAM) dendrimer with cationic lipid-like properties, is utilized in the development of macrophage-targeted nanoparticles (NPs) for agent and vaccine delivery [1] [2]. Target: Others
| CAS | 1510653-27-6 |
| MW: | 1790.91 D |
From 100.00€
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TMV-IN-4
Item number: TGM-T75028-100mg
Description: TMV-IN-4 (Compound 3), a tobacco mosaic virus (TMV) inhibitor, effectively strengthens plant resistance and tolerance to TMV by binding with the TMV helicase. Furthermore, it boosts activities of peroxidase and superoxide dismutase, augmenting tobacco's resilience to TMV infection [1]. Target: Others
| CAS | 1820823-40-2 |
| MW: | 315.36 D |
From 1,298.00€
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HEMTAC CDK4/6 degrader 1
Item number: TGM-T75029-50mg
Description: HEMTAC CDK4/6 degrader 1 is a PROTAC connected by ligands for HSP90 and CDK4/6 with a \( K_d \) value of 35.7 µM. It induces CDK4/6 degradation in B16F10 melanoma cells, arrests the cell cycle at the G0/G1 phase, and induces apoptosis. HEMTAC CDK4/6 degrader 1 can be used in cancer research [1]. Target:...
| CAS | 2821803-61-4 |
| MW: | 953.49 D |
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Ubiquitination-IN-2
Item number: TGM-T75030-50mg
Description: Ubiquitination-IN-2 is a potent inhibitor of E1-E2 protein-protein interactions (PPI), exhibiting inhibitory activity with a dissociation constant (Kd) of 0.72 µM for the ubiquitin E1 (Uba1) enzyme. By blocking the transfer of ubiquitin from E1 to E2, Ubiquitination-IN-2 serves as a valuable tool in...
| MW: | 2346.04 D |
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N4-(n-Palmitoyl)-4'-azido-2'-deoxy-2'-fluoro-arabinocytidine
Item number: TGM-T75032-50mg
Description: N4-(n-Palmitoyl)-4'-azido-2'-deoxy-2'-fluoro-arabinocytidine is a cytidine nucleoside analog with potential anti-metabolic and anti-tumor activities due to its mechanism of inhibiting DNA methyltransferases (such as Zebularine) [1]. Target: Others
| MW: | 524.63 D |
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Adenosine-2-carboxy methyl amide
Item number: TGM-T75033-50mg
Description: Adenosine-2-carboxy methyl amide, a purine nucleoside analogue, exhibits broad antitumor activity against indolent lymphoid malignancies through mechanisms including DNA synthesis inhibition and apoptosis induction.[1]. Target: Others
| MW: | 324.29 D |
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N1-Methylsulfonyl pseudouridine
Item number: TGM-T75034-50mg
Description: N1-Methylsulfonyl pseudouridine, a purine nucleoside analogue, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, among others [1]. Target: Others
| MW: | 322.29 D |
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2'-Chloro-N6-(3-trifluoromethyl)benzyl adenosine
Item number: TGM-T75035-50mg
Description: 2'-Chloro-N6-(3-trifluoromethyl)benzyl adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include inhibition of DNA synthesis and induction of apoptosis, among others [1]. Target: Others
| MW: | 459.81 D |
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N1-(2-Methyl)propyl pseudouridine
Item number: TGM-T75036-50mg
Description: N1-(2-Methyl)propyl pseudouridine, a purine nucleoside analogue, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include DNA synthesis inhibition and apoptosis induction, among others [1]. Target: Others
| MW: | 300.31 D |
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