Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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ALK-IN-21
Item number: TGM-T74522-100mg
Description: ALK-IN-21 (Compound B10), a proficient ALK inhibitor targeting the ALKG1202R mutation, demonstrates significant inhibitory activity with IC50 values of 4.59 nM against ALK WT, 2.07 nM against ALK L1196M, and 5.95 nM against ALK G1202R. Moreover, ALK-IN-21 effectively suppresses proliferation in...
| CAS | 2901889-01-6 |
| MW: | 809.48 D |
From 1,440.00€
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Antifungal agent 29
Item number: TGM-T74526-50mg
Description: Antifungal Agent 29 (compound 9d) is a potent, selective, and non-toxic agent effective against Cryptococcus neoformans, exhibiting an MIC of =0.23 µM [1]. Target: Others
| MW: | 1087.19 D |
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Anti-MRSA agent 4
Item number: TGM-T74527-50mg
Description: Anti-MRSA agent 4 (compound 7a), a selective and potent inhibitor of Gram-positive Methicillin-resistant Staphylococcus aureus (MRSA) growth, demonstrates a minimum inhibitory concentration (MIC) of = 0.26 µM and exhibits neither cytotoxic nor hemolytic activity in HEK293 cells [1]. Target: Others
| MW: | 943.07 D |
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Antibacterial agent 86
Item number: TGM-T74529-50mg
Description: Compound A11 (Antibacterial agent 86) exhibits the highest bacteriostatic activity against methicillin-resistant S. aureus, with minimum inhibitory concentration (MIC) values reaching as low as 0.00191 µg/mL. This efficacy is 162 and 32 times greater than the commercial antibiotics tiamulin and...
| MW: | 587.79 D |
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Antifungal agent 26
Item number: TGM-T74537-50mg
Description: Pradimicin A derivative 26 exhibits antifungal, antiviral, and antiparasitic properties by attaching to d-mannose (Man)-rich glycans in pathogenic organisms [1]. Target: Others
| CAS | 2769834-78-6 |
| MW: | 855.79 D |
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Galectin-3 antagonist 2
Item number: TGM-T74538-100mg
Description: Galectin-3, a beta-galactoside-specific carbohydrate recognition protein (lectin), facilitates the migration of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells and demonstrates resistance to pharmaceutical interventions. Target: Galectin
| CAS | 2921603-02-1 |
| MW: | 461.42 D |
From 1,440.00€
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Anti-inflammatory agent 38
Item number: TGM-T74540-50mg
Description: Anti-inflammatory agent 38 (compound 23d) is a potent Nrf2/HO-1 pathway inhibitor, with an IC 50 value of 0.38 µM for NO . Nrf2/HO-1-IN-1 can significantly reduce the level of ROS in cells. Nrf2/HO-1-IN-1 can be used for researching anti-inflammatory [1] . Target: Others
| MW: | 746.82 D |
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YM458
Item number: TGM-T74542-100mg
Description: YM458, a potent dual inhibitor of EZH2 and BRD4, exhibits IC50 values of 490 nM and 34 nM, respectively. This compound effectively hinders cell proliferation and colony formation, while also inducing cell cycle arrest and apoptosis in solid tumor cells, making it a viable candidate for anticancer...
| CAS | 2770108-93-3 |
| MW: | 957.62 D |
From 1,440.00€
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(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine
Item number: TGM-T74544-50mg
Description: (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual-target PROTAC capable of directing ubiquitination and degradation of Smad3 while also elevating HIF-alpha protein levels, exhibiting multipath anti-fibrotic and renal protective functions, making it valuable for renal anemia research [1]....
| CAS | 2347517-69-3 |
| MW: | 750.91 D |
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FAP-2286 acetate
Item number: TGM-T74547-50mg
Description: FAP-2286 acetate, a conjugate of a fibroblast activation protein (FAP)-binding peptide, exhibits antitumor activity [1]. It can be labeled with radionuclides for diagnostic purposes. Target: Others
| MW: | 1530.83 D |
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Non-PEGylated/naked ARC1905
Item number: TGM-T74552-50mg
Description: ARC1905, a non-PEGylated/naked anti-C5 RNA aptamer, functions by inhibiting the cleavage of complement factor 5 (C5) into its components, C5a and C5b, without PEG conjugation. This compound is currently being researched for its potential application in the treatment of age-related macular degeneration...
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YSK 05
Item number: TGM-T74553-2mg
Description: YSK 05, a pH-sensitive cationic lipid, enhances the intracellular trafficking of non-viral vectors, significantly improves gene silencing and hemolytic activities in its modified form YSK 05-MEND, and effectively overcomes the suppression of endosomal escape caused by PEGylation, thereby enhancing siRNA...
| CAS | 1318793-78-0 |
| MW: | 628.07 D |
65.00€
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