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Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

Go to the catalogs of TargetMol

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11558 from 12311 pages
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GG-43
GG-43

Item number: TGM-T61036-100mg

TargetMol
Description: GG-43 is a potent inhibitor of LIN28. The IC50 value of GG-43 against human LIN28A is 4 µM [1]. Target: Others
MW: 335.4 D
From 1,440.00€ *
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VEGFR-2-IN-10
VEGFR-2-IN-10

Item number: TGM-T61038-100mg

TargetMol
Description: VEGFR-2-IN-10 has enhanced antiangiogenic potency against VEGFR2 phosphorylation induced by VEGF with an IC50 value of 0.7 µM and no cytotoxic effects. Target: Others
MW: 335.4 D
From 1,440.00€ *
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STING agonist-7
STING agonist-7

Item number: TGM-T61043-100mg

TargetMol
Description: STING agonist-7 is an agonist of non-nucleotide STING that binds selectively to mouse STING but not human STING [1]. Target: Others
MW: 336.3 D
From 867.00€ *
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Topoisomerase I/II inhibitor 2
Topoisomerase I/II inhibitor 2

Item number: TGM-T61045-100mg

TargetMol
Description: Topoisomerase I/II inhibitor 2 (compound 1a) is a DNA topoisomerase I/II dual inhibitor that significantly reduces xenograft tumor growth in a mouse model, indicating its potential use in treating liver cancer. It is a potent topoisomerase inhibitor with IC50 values of 6.83 µM and 9.82 µM for LM9 cells...
MW: 336.34 D
From 1,440.00€ *
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AChE-IN-11
AChE-IN-11

Item number: TGM-T61049-100mg

TargetMol
Description: AChE-IN-11 (compound 5C) is a multifunctional agent used in Alzheimer's disease research, exhibiting neuroprotective and antioxidant activity (ORAC = 2.5 eq). It has IC50 values of 7.9 µM, 9.9 µM, and 8.3 µM against AChE, MAO-B, and BACE1, respectively. AChE-IN-11 demonstrates mixed-type AChE inhibition...
MW: 336.43 D
From 1,440.00€ *
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JH295 hydrate
JH295 hydrate

Item number: TGM-T61061-25mg

TargetMol
Description: JH295 hydrate is a potent, irreversible, and selective NIMA-related kinase 2 (Nek2) inhibitor that inhibits cellular Nek2 by Cys22 alkylation (IC50 = 770 nM). JH295 hydrate is not active against the mitotic kinases Cdk1, Aurora B, or Plk1, and does not interfere with bipolar spindle assembly or the...
MW: 338.36 D
2,095.00€ *
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ERGi-USU-6 mesylate
ERGi-USU-6 mesylate

Item number: TGM-T61062-100mg

TargetMol
Description: ERGi-USU-6 (mesylate) is a new selective ERG-positive prostate cancer inhibitor, with an IC50 of 0.089 µM, and is a salt derivative of ERGi-USU-6. Target: Others
MW: 338.38 D
From 1,051.00€ *
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nAChR antagonist 1
nAChR antagonist 1

Item number: TGM-T61064-100mg

TargetMol
Description: nAChR antagonist 1 (compound B15) is a highly effective antagonist of alpha7 nAChR, with an IC50 value of 3.3 µM, making it an ideal candidate for investigating the pathogenesis of schizophrenia, Alzheimer's disease, and inflammatory disorders [1]. Target: Others
MW: 338.4 D
From 1,440.00€ *
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MurB-IN-1
MurB-IN-1

Item number: TGM-T61067-100mg

TargetMol
Description: MurB-IN-1 (compound 44) is a potent inhibitor of MurB, an essential enzyme involved in the synthesis of the bacterial cell wall. With a binding affinity of Kd 3.57 µM, MurB-IN-1 effectively hinders MurB activity, presenting a promising therapeutic option against P. aeruginosa, a highly virulent and...
MW: 339.1 D
From 1,440.00€ *
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KH-259
KH-259

Item number: TGM-T61073-100mg

TargetMol
Description: KH-259 (compound 1) is a highly potent, selective, and CNS-penetrant HDAC6 inhibitor, with an IC50 of 0.26 µM, exerting antidepressant effects in mice by inhibiting HDAC6 within the brain and holding promise as a valuable tool for neurodegenerative diseases research [1]. Target: Others
MW: 339.43 D
From 1,440.00€ *
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Heme Oxygenase-1-IN-2
Heme Oxygenase-1-IN-2

Item number: TGM-T61078-100mg

TargetMol
Description: Heme Oxygenase-1-IN-2, a novel inhibitor of heme oxygenase-1 (HO-1), demonstrates potent antiproliferative activity in vitro with an IC50 value of 0.95 µM. Target: Others
MW: 339.82 D
From 1,440.00€ *
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CYP1B1-IN-2
CYP1B1-IN-2

Item number: TGM-T61082-100mg

TargetMol
Description: CYP1B1-IN-2 (compound 9j) is a highly potent and selective inhibitor of the cytochrome P450 enzyme CYP1B1, exhibiting an IC50 value of 0.52 nM [1]. Target: Others
MW: 340.3 D
From 1,440.00€ *
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11558 from 12311 pages
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