Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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11557 from 12311 pages
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Tubulin inhibitor 14
Tubulin inhibitor 14

Item number: TGM-T60402-100mg

Description: Tubulin inhibitor 14 is a potent inhibitor of NQO2 (quinone oxidoreductase 2) with an IC50 of 1.0 µM, which also inhibits tubulin polymerization and the formation of endothelial cell capillary-like tubes. As a microtubule destabilizer, Tubulin inhibitor 14 has potential tumor-selective, anti-angiogenic,...
MW: 257.23 D
From 1,440.00€ *
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COX-2/NO-IN-1
COX-2/NO-IN-1

Item number: TGM-T60403-100mg

Description: COX-2/NO-IN-1 is an orally active nitric oxide synthase (iNOS) and NO (IC50 of 3.52 µM) inhibitor that also suppresses COX-2 expression, exhibiting anti-inflammatory effects and reducing pathological damage to kidney tissues [1]. Target: Others
MW: 257.28 D
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DL-Buthionine-(S,R)-sulfoximine hydrochloride
DL-Buthionine-(S,R)-sulfoximine hydrochloride

Item number: TGM-T60406-25mg

Description: DL-Buthionine-(S,R)-sulfoximine hydrochloride (Buthionine sulfoximine hydrochloride) is a potent and specific inhibitor of glutamylcysteine synthetase biosynthesis. Target: Others
MW: 258.77 D
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L-Buthionine-(S,R)-sulfoximine hydrochloride
L-Buthionine-(S,R)-sulfoximine hydrochloride

Item number: TGM-T60407-25mg

Description: L-Buthionine-(S,R)-sulfoximine hydrochloride is a potent, cell-permeable, fast-acting, irreversible inhibitor of G-glutamylcysteine synthetase (gamma-GCS) that depletes cellular glutathione levels. It has IC50s of 1.9 µM, 8.6 µM, and 29 µM in melanoma, breast, and ovarian tumor specimens, respectively...
MW: 258.77 D
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hCA VB-IN-1
hCA VB-IN-1

Item number: TGM-T60408-100mg

Description: hCA VB-IN-1 (compound 15) is a potent and selective inhibitor of carbonic anhydrase (hCA VB) with a KI of 515.7 nM [1]. Target: Others
MW: 259.28 D
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DS34942424
DS34942424

Item number: TGM-T60415-100mg

Description: DS34942424 is an orally potent analgesic that does not exhibit mu opioid receptor agonist activity. Target: Others
MW: 260.31 D
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CRM1 degrader 1
CRM1 degrader 1

Item number: TGM-T60416-100mg

Description: CRM1 degrader 1 (1l) is a low-toxicity CRM1 degrader that induces apoptosis in gastric carcinoma and selectively inhibits the proliferation of gastric cancer[1]. Target: Others
MW: 260.33 D
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NF-kappaB-IN-6
NF-kappaB-IN-6

Item number: TGM-T60433-100mg

Description: NF-kappaB-IN-6 (Compound 3d) is an anti-inflammatory agent that suppresses the NF-kappaB signaling pathway, thereby reducing iNOS and COX-2 protein expression. It inhibits NO production in LPS-induced RAW264.7 cells with an IC50 of 23.1 µM[1]. Target: Others
MW: 264.32 D
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Tubulin inhibitor 17
Tubulin inhibitor 17

Item number: TGM-T60436-100mg

Description: Tubulin inhibitor 17 (Compound 3b) is an inhibitor of tubulin polymerization (IC50 = 12.38 µM) that exhibits anticancer activities and induces cell apoptosis[1]. Target: Others
MW: 264.32 D
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Nurr1 agonist 1
Nurr1 agonist 1

Item number: TGM-T60443-100mg

Description: Nurr1 agonist 1 is an inverse agonist tool for the neuroprotective transcription factor Nurr1 which is an appealing target to treat neurodegenerative diseases. Target: Others
MW: 266.29 D
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hA3AR agonist 1
hA3AR agonist 1

Item number: TGM-T60444-100mg

Description: hA3AR agonist 1 is a potent human A3 adenosine receptor (hA3AR) agonist with a Ki of 2.40 nM. Target: Others
MW: 266.32 D
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17beta-HSD1-IN-1
17beta-HSD1-IN-1

Item number: TGM-T61034-100mg

Description: 17beta-HSD1-IN-1 (Compound 1) is a highly selective inhibitor of 17beta-HSD1 with IC50 values of 5.6 nM for 17beta-HSD1 and 3155 nM for 17beta-HSD2, and it can be used in non-small cell lung cancer (NSCLC) research [1]. Target: Others
MW: 335.4 D
From 871.00€ *
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11557 from 12311 pages