Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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(H)S(OMe)-DFR-kbt
Item number: TGM-T207199-10mg
Description: (H)S(OMe)-DFR-kbt (compound 9) is a potent selective inhibitor of TMPRSS2, with a Ki value of 0.13 nM. It is utilized in research related to SARS-CoV-2. Target: SARS-CoV
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TriDAP dihydrochloride
Item number: TGM-T207223-10mg
Description: TriDAP dihydrochloride (L-Ala-gamma-D-Glu-meso-diaminopimelic acid dihydrochloride) is the dihydrochloride salt form of TriDAP. It is a bioactive peptide and serves as a specific NOD1 activator. Target: NOD-like Receptor (NLR)
| Keywords: | L-Ala-gamma-D-Glu-meso-diaminopimelic acid dihydrochloride |
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Succinate dehydrogenase-IN-9
Item number: TGM-T207231-10mg
Description: Succinate dehydrogenase-IN-9 (Compound Iik) is an inhibitor of succinate dehydrogenase with an IC50 of 3.6 µM. It demonstrates strong inhibitory activity against various fungi, such as S. sclerotiorum, with an EC50 of 1.14 µg/mL. Additionally, Succinate dehydrogenase-IN-9 enhances nitrate reductase...
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NHE-1-IN-2
Item number: TGM-T207240-10mg
Description: NHE-1-IN-2 (compound 7g) is a potent NHE-1 inhibitor with an IC50 of 0.78 µM. It mitigates left ventricular systolic dysfunction in mouse models of heart failure. Target: Sodium Channel
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CTW0419
Item number: TGM-T207242-10mg
Description: CTW0419 is an effective positive allosteric modulator (PAM) of the 5-HT receptor, showing promise in research related to neuropsychiatric disorders. Target: 5-HT Receptor
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PBRM1/SMARCA2,4 binder-1
Item number: TGM-T207244-10mg
Description: PBRM1/SMARCA2,4 binder-1 is an agent that binds to PBRM1, SMARCA2, and SMARCA4, with IC50 values of 0.083 µM, 0.153 µM, and 0.046 µM, respectively. Target: Epigenetic Reader Domain
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Cy3-Asiatic acid
Item number: TGM-T207251-10mg
Description: Cy3-Asiatic acid is a fluorescent labeling agent formed by the combination of Cy3 and Asiatic acid. It allows for the observation and tracking of Asiatic acid under a fluorescence microscope (Ex/Em = 550/570 nm). Target: Others
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Heparin-Cy5
Item number: TGM-T207273-10mg
Description: Heparin-Cy5 is a fluorescent dye comprising CY5 and heparin. It is utilized to study the localization, distribution, and interactions of heparin with other biomolecules within biological systems (Ex/Em = 633/670 nm). Target: Others
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Antileishmanial agent-33
Item number: TGM-T206081-10mg
Description: Antileishmanial agent-33 (4e) is a hybrid compound of grandisin and machilin G, demonstrating moderate activity against promastigotes with an IC50 of 38.1 µM. In studies of cutaneous leishmaniasis (CL), Antileishmanial agent-33 (4e) has shown potential as an antileishmanial agent. Target: Parasite
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Poly-L-lysine-Ahx-FITC (MW 15000-30000)
Item number: TGM-T207003-10mg
Description: Poly-L-lysine-Ahx-FITC (MW 15000-30000) is a cationic polymer and a polylysine modified with FITC. This compound is employed to affix cells onto glass substrates or negatively charged surfaces for subsequent experimental labeling and positioning.
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WEHI-P8
Item number: TGM-T207007-10mg
Description: WEHI-P8 is an orally active inhibitor targeting the coronavirus papain-like protease (PLpro). It inhibits SARS-CoV-2 PLpro with an IC50 of 12 nM and demonstrates excellent cellular activity with an EC50 of 298 nM. Additionally, WEHI-P8 has protective effects in mice against prolonged lung and brain...
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BTR2004
Item number: TGM-T207008-10mg
Description: BTR2004 is a selective PROTAC degrader targeting the BET family (BRD2/3/4) proteins. It facilitates the formation of a ternary complex with BRD proteins and KLHL20, leading to ubiquitination and proteasomal degradation via the UPS pathway. BTR2004 shows potential for research in PC3 prostate cancer and...
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