Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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SDZ 21009
Item number: TGM-T23343-100mg
Description: beta-adrenoceptor and 5-HT1A/1B receptor antagonist. Target: Others. Smiles: O(CC(CNC(C)(C)C)O)C1=C2C(NC(C(OC(C)C)=O)=C2)=CC=C1
| CAS | 39731-05-0 |
| MW: | 348.44 D |
From 1,440.00€
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SDZ 220-040
Item number: TGM-T23344-100mg
Description: SDZ 220-040 is a selective mammalian NMDA receptor antagonist that induces a partially gravity-free mode of root growth. Target: NMDAR. Smiles: ClC1=C(C2=CC(C[C@@H](C(O)=O)N)=C(O)C(CP(=O)(O)O)=C2)C=CC(Cl)=C1. References: Brian G Forde. et al. Glutamate signalling via a MEKK1 kinase-dependent pathway...
| Keywords: | SDZ-220-040 |
| CAS | 174575-40-7 |
| MW: | 420.18 D |
From 58.00€
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SDZ 220-040 ammonium
Item number: TGM-T23344L-100mg
Description: SDZ 220-040 ammonium is a competitive glutamate ionotropic receptor NMDA antagonist used in the study of neurological disorders. Target: NMDAR. Smiles: ClC1=C(C=CC(Cl)=C1)C2=CC(C[C@H](N)C(O)=O)=C(C(CP(O)([O-])=O)=C2)O.[NH4+]. References: Brian G Forde. et al. Glutamate signalling via a MEKK1...
| Keywords: | SDZ 220-040 ammonium (174575-40-7 Free base) |
| MW: | 437.21 D |
From 244.00€
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SDZ NKT 343
Item number: TGM-T23345-100mg
Description: human tachykinin NK1 receptor antagonist. Target: Others. Smiles: C(N[C@@H](CC1=CC2=C(C=C1)C=CC=C2)C(N(CC3=CC=CC=C3)C)=O)(=O)[C@H]4N(C(NC5=C(N(=O)=O)C=CC=C5)=O)CCC4
| CAS | 180046-99-5 |
| MW: | 579.65 D |
From 1,440.00€
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SDZ SER 082 fumarate
Item number: TGM-T23346-100mg
Description: 5-HT2B/2C receptor antagonist. Target: Others. Smiles: CN1C[C@]2(C=3C=4N(C[C@]2(CC1)[H])CCC4C=CC3)[H]
| CAS | 141474-54-6 |
| MW: | 228.33 D |
From 1,725.00€
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SDZ WAG 994
Item number: TGM-T23347-100mg
Description: SDZ WAG 994 is an A1 adenosine receptor agonist. Target: Adenosine Receptor. Smiles: O(C)[C@H]1[C@H](N2C=3C(N=C2)=C(NC4CCCCC4)N=CN3)O[C@H](CO)[C@H]1O
| CAS | 130714-47-5 |
| MW: | 363.41 D |
From 57.00€
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SEN12333
Item number: TGM-T23348-100mg
Description: SEN12333 is an alpha7 nicotinic acetylcholine receptor (nAChR) agonist. Target: AChR. Smiles: O=C(CCCCN1CCOCC1)Nc1ccc(cc1)-c1cccnc1
| Keywords: | SEN 12333 |
| Application: | nAChR alpha7 agonist |
| CAS | 874450-44-9 |
| MW: | 339.43 D |
From 32.00€
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SGS518 oxalate
Item number: TGM-T23350-100mg
Description: SGS518 oxalate is a 5-HT6 antagonist. Target: Others. Smiles: O=C(O)C(=O)O.O=S(=O)(OC=1C=CC2=C(C1)C(=CN2C)C3CCN(C)CC3)C=4C(F)=CC=CC4F
| Keywords: | SGS 518 oxalate |
| CAS | 445441-27-0 |
| MW: | 510.51 D |
From 1,440.00€
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MDL-28170
Item number: TGM-T2470-100mg
Description: MDL-28170 (Calpain Inhibitor III) is a cysteine protease. Target: Proteasome, Cysteine Protease. Smiles: CC(C)C(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C=O. References: Li PA, et al. Postischemic treatment with calpain inhibitor MDL 28170 ameliorates brain damage in a gerbil model of global ischemia....
| Keywords: | Calpain Inhibitor III |
| Application: | Calpain 1 and 2 inhibitor |
| CAS | 88191-84-8 |
| MW: | 382.45 D |
From 30.00€
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MK-8745
Item number: TGM-T2471-10mg
Description: MK-8745 is a potent and selective Aurora A inhibitor. Target: Apoptosis, Aurora Kinase. Smiles: Fc1c(Cl)cccc1C(=O)N1CCN(Cc2cccc(Nc3nccs3)n2)CC1. References: Chowdhury A, et al. Leuk Lymphoma. 2012, 53(3), 462-471.
| Application: | Aurora A kinase inhibitor |
| CAS | 885325-71-3 |
| MW: | 431.91 D |
From 33.00€
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CGI-1746
Item number: TGM-T2472-100mg
Description: CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM. Target: BTK, Autophagy. Smiles: CC1=C(C=CC=C1NC(=O)C2=CC=C(C(C)(C)C)C=C2)C=3N=C(NC4=CC=C(C(=O)N5CCOCC5)C=C4)C(=O)N(C)C3. References: Di Paolo JA, et al. Nat Chem Biol, 2011, 7(1):41-50.
| Application: | Btk inhibitor |
| CAS | 910232-84-7 |
| MW: | 579.69 D |
From 33.00€
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PLX-4720
Item number: TGM-T2473-100mg
Description: PLX-4720, a potent and selective inhibitor of B-Raf (V600E) with an IC50 of 13 nM, is equally effective against c-Raf-1 (Y340D and Y341D mutations). Target: Raf. Smiles: CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c1F. References: Tsai J, et al. Discovery of a selective inhibitor of oncogenic B-Raf...
| Keywords: | PLX4720 |
| Application: | B-Raf (V600E) / c-Raf-1 (Y340D/Y341D) inhibitor |
| CAS | 918505-84-7 |
| MW: | 413.83 D |
From 31.00€
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