Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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P1D-34
Item number: TGM-T206664-10mg
Description: P1D-34 is a Pin1 PROTAC degrader with a DC50 value of 177 nM. It downregulates Pin1 substrate proteins, including Cyclin D1, Rb, Mcl-1, Akt, and c-Myc. Additionally, P1D-34 exhibits antiproliferative activity across various acute myeloid leukemia (AML) cell lines and induces DNA damage and apoptosis by...
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AS-0017445
Item number: TGM-T206668-10mg
Description: AS-0017445 is an inhibitor targeting the main protease of the coronavirus and the virus causing Middle East Respiratory Syndrome (MERS). It functions by inhibiting viral protein processing within host cells, thereby preventing viral replication. Target: SARS-CoV, Virus Protease
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FITC-PEG-biotin (MW 3400)
Item number: TGM-T206684-10mg
Description: FITC-PEG-biotin (MW 3400) is a fluorescent dye composed of poly(ethylene glycol) (PEG), FITC, and Biotin. It is used for fluorescence labeling and imaging.
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UNC8212
Item number: TGM-T206686-10mg
Description: UNC8212 is a potent TAM kinase inhibitor. It exhibits strong inhibitory activity against MERTK and AXL", with IC50 values of 1.5 nM and 1.3 nM, respectively," and also inhibits TYRO3 with an IC50 of 6.7 nM. By targeting the structurally diverse """"back-pocket"""" region within the TAM kinase family","...
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FITC-PEG-biotin (MW 400)
Item number: TGM-T206687-10mg
Description: FITC-PEG-biotin (MW 400) is a fluorescent dye composed of polyethylene glycol (PEG), FITC, and Biotin. This compound is suitable for applications in fluorescence labeling and imaging.
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Anticancer agent 270
Item number: TGM-T206688-10mg
Description: Anticanceragent 270 (Compound 8e) is a microtubule protein inhibitor with an IC50 of 1.02 µM against MCF-7 breast cancer cells. It exerts significant antiproliferative activity on breast cancer cells through a dual mechanism of inducing apoptosis and destabilizing microtubules. Anticanceragent 270 is...
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FITC-PEG-N3 (MW 400)
Item number: TGM-T206689-10mg
Description: FITC-PEG-N3 (MW 400) is an azide-containing fluorescent dye that incorporates polyethylene glycol (PEG) and FITC. Serving as a click chemistry reagent, it features azide groups enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can...
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Chitosan-Cy7 (MW 7000)
Item number: TGM-T206690-10mg
Description: Chitosan-Cy7 (MW 7000) is a form of chitosan labeled with Cy7. It is suitable for applications in fluorescent labeling and imaging.
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c-Kit-IN-9
Item number: TGM-T206716-10mg
Description: c-Kit-IN-9 (Compound D9) is an inhibitor of c-Kit. It suppresses inflammation in J774A.1, RAW264.7, MPMs cells, and lung tissue by blocking LPS-induced NF-kappaB pathway activation. Additionally, c-Kit-IN-9 demonstrates effective anti-inflammatory activity in mouse models of acute lung injury and...
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FITC-PEG-COOH (MW 400)
Item number: TGM-T206719-10mg
Description: FITC-PEG-COOH (MW 400) is a fluorescent dye comprised of polyethylene glycol (PEG), FITC, and a carboxyl group (COOH). FITC-PEG-COOH (MW400) is suitable for fluorescent labeling and imaging.
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4-arm-PEG-FITC (MW 5000)
Item number: TGM-T206756-10mg
Description: 4Arm-PEG-FITC (MW 5000) is a fluorescent dye composed of polyethylene glycol (PEG) and four FITC groups. It is utilized for fluorescent labeling and imaging.
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Neuroprotective agent 10
Item number: TGM-T206759-10mg
Description: Neuroprotective agent 10 (Compound 11c) is a brain-penetrant neuroprotective compound. It effectively scavenges ABTS radicals (IC50 for scavenging: 9.20 µM), DPPH radicals (IC50 for scavenging: 7.09 µM), and superoxide anion radicals (inhibition rate: 48.4%). Additionally, it mitigates oxidative damage...
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