Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Rifamycin W
Item number: TGM-TN10046-10mg
Description: Rifamycin W exhibits activity against Gram-positive bacteria. Target: Antibacterial. Smiles: O=C1C=C2NC(=O)C(=CC=CC(C)C(O)C(C)C(O)C(C)C(O)C(C)C(O)C(C=C(C(=O)C3=C(O)C(=C(O)C(C2=O)=C13)C)C)CO)C
| MW: | 655.732 D |
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Ericamycin
Item number: TGM-TN10047-10mg
Description: Ericamycin is an antibiotic with antibacterial activity against Gram-positive bacteria. It effectively inhibits Staphylococcus aureus, with a minimum inhibitory concentration (MIC) ranging from 0.004 to 0.016 µg/mL. Target: Antibacterial, Antibiotic. Smiles:...
| MW: | 499.468 D |
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Rhetsinine
Item number: TGM-TN10048-10mg
Description: Rhetsinine is an aldose reductase inhibitor identified in Evodia rutaecarpa, with an IC50 value of 24.1 µM. At a concentration of 100 µM, Rhetsinine significantly reduces sorbitol accumulation, achieving an inhibition rate of 79.3%. This compound is applicable in research concerning diabetic...
| MW: | 319.357 D |
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Espicufolin
Item number: TGM-TN10049-10mg
Description: Espicufolin is a neuroprotective compound found in Streptomyces sp:cu39. It inhibits glutamate toxicity, thereby reducing or overcoming ischemic brain injury, with an EC50 value of 40 nM for toxicity in N18-RE-105 cells. Espicufolin can be utilized in research on neurodegenerative diseases. Smiles:...
| MW: | 378.375 D |
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Dihydromevinolin
Item number: TGM-TN10050-10mg
Description: Dihydromevinolin is a potent cholesterol-lowering metabolite produced by Aspergillus terreus. It functions as an HMG-CoA reductase inhibitor. Target: HMG-CoA Reductase, Endogenous Metabolite. Smiles: O(C([C@H](CC)C)=O)[C@@H]1[C@]2([C@@](C=C[C@H](C)[C@@H]2CC[C@@H]3C[C@@H](O)CC(=O)O3)(C[C@H](C)C1)[H])[H]
| Keywords: | 4a,5-Dihydromevinolin , Lovastatin EP impurity E |
| MW: | 406.556 D |
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Chrymutasin B
Item number: TGM-TN10051-10mg
Description: Chrymutasin B is a glycoside antitumor antibiotic known for its cytotoxic properties. Target: Antibiotic, Antibacterial. Smiles: O=C1C=2C=3C4=C(C(=O)C2N)C=CC(C)=C4C(=O)OC3C=5C1=CC=CC5O[C@H]6[C@H](O[C@@H]7[C@H](O)[C@@H](O)[C@@H](O)[C@@H](C)O7)[C@@H](O)[C@@H](O)[C@@H](C)O6
| MW: | 637.587 D |
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Saricandin
Item number: TGM-TN10052-10mg
Description: Saricandin exhibits moderate antifungal activity. It inhibits glucan synthase with an ID50 of 242.0 µg/mL. Target: Antifungal. Smiles: O[C@H]1[C@]2(C=3C(CO2)=CC(O)=CC3O)O[C@H](CO)[C@@H](O[C@@H]4O[C@H](COC(/C=C/C5=CC=CC=C5)=O)[C@H](O)[C@H](O)[C@H]4O)[C@@H]1OC(/C=C/C=C/CC(/C=C/C=C/CCCCC)O)=O
| MW: | 838.89 D |
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Respinomycin A1
Item number: TGM-TN10053-10mg
Description: Respinomycin A1 is an antibiotic found in the Streptomyces sp. RK-483 strain. It has the capability to induce differentiation in leukemia K-562 cells. Target: Antibacterial. Smiles:...
| MW: | 1033.12 D |
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Leptofuranin B
Item number: TGM-TN10054-10mg
Description: Leptofuranin B is found in the Str. tanashiensis strain and can cause normal cells to arrest and lead to cell death. Target: Antibiotic. Smiles: C(C(C(/C=C(/C=C/CC(/C=C(\C=C\C1C(C)C=CC(=O)O1)/CC)C)\C)C)=O)(C)C2OC(CCO)(C)CC2C
| MW: | 526.747 D |
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Fusarubin
Item number: TGM-TN10055-10mg
Description: Fusarubin is a metabolite produced by Fusarium species. Smiles: O=C1C2=C(O)C=C(OC)C(O)=C2C(=O)C3=C1COC(O)(C)C3
| MW: | 306.267 D |
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Pradimicinone I
Item number: TGM-TN10056-10mg
Description: Pradimicinone I (Compound 10), an analogue of Pradimicin A, is an antibiotic with potential applications in antimicrobial research. Target: Antibacterial, Antibiotic. Smiles: O=C(O)C(NC(=O)C1=C(O)C=2C3=C(O)C=4C(=O)C5=CC(OC)=CC(O)=C5C(=O)C4C=C3C(O)C(O)C2C=C1C)C
| MW: | 549.482 D |
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Cochleamycin A
Item number: TGM-TN10057-10mg
Description: Cochleamycin A exhibits strong inhibitory activity against tumor cells, with IC50 values (µg/mL) of 1.6, 14.0, 6.2, 16.5, and 19.1 for P388, HL60, K562, COL0205, and HT29 cells, respectively. Additionally, Cochleamycin A possesses activity against Gram-positive bacteria. Target: Antibiotic,...
| MW: | 374.427 D |
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