Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Ixazomib citrate
Item number: TGM-T8397-25mg
Description: Ixazomib citrate (MLN9708) is a prodrug of Ixazomib (MLN-2238) and an orally bioavailable second-generation proteasome inhibitor with an IC50 of 3.4 nM, exhibiting potential antineoplastic activity. Target: Proteasome, Autophagy. Smiles:...
| Keywords: | MLN9708 |
| Application: | Targets 20S proteasome subunit beta 5 [EC:3.4.25.1] (PSMB5) |
| CAS | 1239908-20-3 |
| MW: | 517.12 D |
From 41.00€
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C14-4
Item number: TGM-T84756-10mg
Description: C14-4, an ionizable lipid utilized in lipid nanoparticles (LNPs) formulation, has been recognized for its efficacy in transfection and minimal cytotoxicity. Target: Others. Smiles: C(CN(CCOCCN(CC(CCCCCCCCCC CC)O)CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O)N1CCN(CCOCCN(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O)CC1
| Keywords: | C14-494 |
| CAS | 2639634-80-1 |
| MW: | 1365.3 D |
303.00€
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Chloroquine
Item number: TGM-T8689-100mg
Description: Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the treatment of malaria and rheumatoid arthritis. Chloroquine also has anti-SARS-CoV-2 (COVID-19) activity and anti-HIV-1 activity. Target: TLR,...
| Keywords: | CQ |
| Application: | Antimalarial, Amebicide |
| CAS | 54-05-7 |
| MW: | 319.87 D |
From 44.00€
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ALC-0315
Item number: TGM-T9277-100mg
Description: ALC-0315 is an ionizable amino lipid that has been used in combination with other lipids to form lipid nanoparticles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine. Target: Others. Smiles: CCCCCCCCC(CCCCCC)C(=O)OCCCCCCN(CCCCO)CCCCCCOC(=O)C(CCCCCC)CCCCCCCC. References:...
| CAS | 2036272-55-4 |
| MW: | 766.27 D |
From 54.00€
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colchiceine
Item number: TGM-TC0037-10mg
Description: colchiceine has a wide range of applications in life science related research. Target: Others, Microtubule Associated. Smiles: COC1=CC2=C(C(OC)=C1OC)C1=CC=C(O)C(=O)C=C1[C@H](CC2)NC(C)=O
| CAS | 477-27-0 |
| MW: | 385.41 D |
From 60.00€
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Sakuranetin
Item number: TGM-TN1126-5mg
Description: Sakuranetin, a flavanone phytoalexin from ultraviolet-irradiated rice leaves, it has antifungal, antimutagenic, anti-inflammatory and antioxidant effects. Target: Antifungal, VEGFR, NF-kappaB, PPAR. Smiles: COc1cc(O)c2C(=O)C[C@H](Oc2c1)c1ccc(O)cc1. References: Analysis on blast fungus-responsive...
| CAS | 2957-21-3 |
| MW: | 286.28 D |
From 39.00€
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Cenicriviroc
Item number: TGM-TQ0297-100mg
Description: Cenicriviroc (TAK-652) is an orally active, dual CCR2/CCR5 antagonist that inhibits both HIV-1 and HIV-2, exhibiting potent anti-infective and anti-inflammatory activity. Target: CCR, HIV Protease. Smiles: CCCCOCCOc1ccc(cc1)-c1ccc2N(CC(C)C)CCC\C(=C/c2c1)C(=O)Nc1ccc(cc1)S(=O)Cc1cncn1CCC. References:...
| Keywords: | TAK-652, TBR-652 |
| Application: | Targets C-C chemokine receptor type 5 (CCR5, CD195) |
| CAS | 497223-25-3 |
| MW: | 696.94 D |
From 59.00€
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Bradykinin
Item number: TGM-TP1277-5mg
Description: Bradykinin is an inflammatory mediator. It is a peptide that causes blood vessels to dilate (enlarge) via the release of prostacyclin, nitric oxide, and Endothelium-Derived Hyperpolarizing Factor. Bradykinin is a physiologically and pharmacologically active peptide of the kinin group of proteins,...
| CAS | 58-82-2 |
| MW: | 1060.21 D |
From 55.00€
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TB500
Item number: TGM-TP1328-50mg
Description: TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4. Target: Others. Smiles: CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(O)=O
| CAS | 885340-08-9 |
| MW: | 889.01 D |
From 33.00€
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Y-27632
Item number: TGM-T1870-100mg
Description: Y-27632 is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells. Target: Apoptosis, ROCK. Smiles: C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc1ccncc1. References: Wu Y, et al. ROCK inhibitor Y27632...
| Application: | Rho kinase (ROCK) inhibitor |
| CAS | 146986-50-7 |
| MW: | 247.34 D |
From 32.00€
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Aprepitant
Item number: TGM-T1743-50mg
Description: Aprepitant (Aprepitant`) is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and Cytochrome P450 3A4 Inducer. Target: Neurokinin receptor, HIV Protease,...
| Keywords: | Aprepitant`, MK-0869, L-754030, MK-869 |
| Application: | Targets tachykinin receptor 1 (TACR1) |
| CAS | 170729-80-3 |
| MW: | 534.43 D |
From 46.00€
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Nintedanib
Item number: TGM-T1777-200mg
Description: Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRalpha, and PDGFRbeta (IC50=59/65 nM). Nintedanib has antitumor activity and inhibits tumor growth by inhibiting angiogenesis....
| Keywords: | BIBF 1120, Intedanib |
| Application: | Targets FMS-like tyrosine kinase 1 [EC:2.7.10.1] (FLT1, VEGFR1) |
| CAS | 656247-17-5 |
| MW: | 539.62 D |
From 37.00€
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