Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Fenebrutinib HCl
Item number: TGM-TQ0242L-25mg
Description: Fenebrutinib is orally available inhibitor of Bruton's tyrosine kinase (BTK) with antineoplastic activity. Upon administration, GDC-0853 inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents both B-cell activation and BTK-mediated...
| Keywords: | GDC 0853, RG 7845, GDC-0853, GDC0853, RG7845, RG-7845 |
| CAS | 2128304-54-9 |
| MW: | 701.27 D |
1,440.00€
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ND-646
Item number: TGM-TQ0243-100mg
Description: ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2, with IC50 values of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively. Target: Acetyl-CoA Carboxylase. Smiles: COc1ccccc1[C@H](Cn1c2sc(c(C)c2c(=O)n(c1=O)C(C)(C)C(N)=O)-c1ncco1)OC1CCOCC1. References:...
| Application: | Acetyl-CoA carboxylase inhibitor |
| CAS | 1434639-57-2 |
| MW: | 568.64 D |
From 73.00€
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Calcipotriol monohydrate
Item number: TGM-TQ0244-100mg
Description: Calcipotriol monohydrate is an analog of Vitamin D3 with a high affinity for the vitamin D receptor. Calcipotriol monohydrate can be used for studies about psoriasis. Target: Others. Smiles: O.[H][C@@]12CC[C@H]([C@H](C)\C=C\[C@@H](O)C3CC3)[C@@]1(C)CCC\C2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C. References:...
| Application: | Targets vitamin D3 receptor (VDR, NR1I1) |
| CAS | 147657-22-5 |
| MW: | 430.62 D |
From 45.00€
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Sapacitabine
Item number: TGM-TQ0245-2mg
Description: Sapacitabine (CS682) is an orally available nucleoside analog precursor compound with potential anti-tumor activity for the study of acute myeloid leukemia. Target: Nucleoside Antimetabolite/Analog. Smiles: CCCCCCCCCC CCCCCC(=O)Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2C#N)c(=O)n1. References: Serova M,...
| Keywords: | CYC682, CS682 |
| Application: | Antineoplastic, Antimetabolite |
| CAS | 151823-14-2 |
| MW: | 490.64 D |
37.00€
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Flurandrenolide
Item number: TGM-TQ0246-2mg
Description: Fludroxycortide, a synthetic topical steroid, serves as an anti-inflammatory treatment for skin irritations. Target: Others. Smiles: [H][C@@]12C[C@@]3([H])[C@]4([H])C[C@H](F)C5=CC(=O)CC[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1(OC(C)(C)O2)C(=O)CO
| Keywords: | Flurandrenolone, Fludroxycortide |
| Application: | Targets glucocorticoid receptor (NR3C1, GR) |
| CAS | 1524-88-5 |
| MW: | 436.51 D |
78.00€
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7-Epi-docetaxel
Item number: TGM-TQ0247-10mg
Description: 7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel. Target: Others. Smiles: CC(=O)O[C@@]12CO[C@@H]1C[C@@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)c2ccccc2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c3ccccc3)C(C)=C([C@@H](O)C1=O)C2(C)C
| Keywords: | 7-Epitaxotere, 4-epi-Docetaxel, 7-Epidocetaxel |
| CAS | 153381-68-1 |
| MW: | 807.88 D |
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Alisol F
Item number: TGM-TQ0248-10mg
Description: Alisol F is a natural product from Alisma plantago-aquatica Linn and has many activities. Target: HBV. Smiles: [H][C@]12C[C@@]3(C)C(C[C@H](O)[C@@]4([H])[C@@]5(C)CCC(=O)C(C)(C)[C@]5([H])CC[C@]34C)=C1[C@H](C)C[C@]([H])(O2)[C@@H](O)C(C)(C)O. References: H Matsuda, et al. Effects of sesquiterpenes and...
| CAS | 155521-45-2 |
| MW: | 488.7 D |
From 74.00€
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Alisol G
Item number: TGM-TQ0249-10mg
Description: Alisol G (25-Anhydroalisol A) is isolated from Rhizoma Alismatis and exhibits hCE2 inhibitory effects. Target: hCE. Smiles: [H][C@@]12CC[C@@]3(C)[C@@]([H])([C@@H](O)CC4=C(CC[C@]34C)[C@H](C)C[C@H](O)[C@@H](O)C(C)=C)[C@@]1(C)CCC(=O)C2(C)C. References: Zhen-Peng Mai, et al. Biotransformation of alisol G by...
| Keywords: | 25-Anhydroalisol A, Alisol-G |
| CAS | 155521-46-3 |
| MW: | 472.7 D |
From 76.00€
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CWHM-12
Item number: TGM-TQ0250-100mg
Description: CWHM-12 is a potent inhibitor of alphaV integrins, with IC50 values of 0.2, 0.8, 1.5, and 1.8 nM for alphavbeta8, alphavbeta3, alphavbeta6, and alphavbeta1, respectively. Target: Integrin. Smiles: CC(C)(C)c1cc(Br)cc(c1)[C@H](CC(O)=O)NC(=O)CNC(=O)c1cc(O)cc(NC2=NCC(O)CN2)c1. References: Henderson NC, et...
| Application: | Integrin alpha-V inhibitor |
| CAS | 1564286-55-0 |
| MW: | 590.47 D |
From 33.00€
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(Z)-2-decenoic acid
Item number: TGM-TQ0251-100mg
Description: (Z)-2-decenoic acid (cis-dec-2-enoic acid) is an unsaturated short-chain fatty acid secreted by Pseudomonas aeruginosa. It can induce a dispersion response in biofilms formed by gram-negative and gram-positive bacteria and can also inhibit biofilm development. Target: Others. Smiles: CCCCCCCC=CC(O)=O....
| Keywords: | (Z)-dec-2-enoic acid, cis-2-Decenoic acid, cis-dec-2-enoic acid |
| CAS | 15790-91-7 |
| MW: | 170.25 D |
From 37.00€
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BAR502
Item number: TGM-TQ0252-100mg
Description: BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 µM and 2 µM). Target: GPCR19, Autophagy, FXR. Smiles: CC[C@H]1[C@@H](O)[C@H]2[C@@H]3CC[C@H]([C@H](C)CCO)[C@@]3(C)CC[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12. References: Cipriani S, et al. Impaired Itching Perception in Murine Models of Cholestasis Is...
| Application: | GPBAR1 /FXR dual agonist |
| CAS | 1612191-86-2 |
| MW: | 392.62 D |
From 39.00€
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PLX51107
Item number: TGM-TQ0253-100mg
Description: PLX51107 is a potent and selective BET inhibitor with Kds of 1.6, 2.1, 1.7, and 5 nM for BRD2-BD1, BRD3-BD1, BRD4-BD1, and BRDT-BD1, respectively. Target: Epigenetic Reader Domain. Smiles: C[C@@H](c1ccccn1)n1cc(-c2ccc(cc2)C(O)=O)c2ncc(cc12)-c1c(C)noc1C. References: Ozer HG, et al. BRD4 Profiling...
| Application: | BET family protein inhibitor |
| CAS | 1627929-55-8 |
| MW: | 438.48 D |
From 48.00€
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