Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
No results were found for the filter!
Phorbol 12-myristate 13-acetate
Item number: TGM-TQ0198-100mg
Description: Phorbol 12-myristate 13-acetate (PMA), a member of the phorbol ester group of natural products, activates PKC, SphK, and NF-kappaB, and induces THP1 cell differentiation. Target: PKC, S1P Receptor, NF-kappaB. Smiles:...
| Keywords: | PMA |
| MW: | 616.83 D |
From 42.00€
*
Paricalcitol
Item number: TGM-TQ0200-100mg
Description: Paricalcitol is a vitamin D receptor agonist. It is used for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure. Target: Others. Smiles: [H][C@@]12CC[C@H]([C@H](C)\C=C\[C@H](C)C(C)(C)O)[C@@]1(C)CCC\C2=C/C=C1C[C@@H](O)C[C@H](O)C1. References:...
| Application: | Targets vitamin D3 receptor (VDR, NR1I1) |
| CAS | 131918-61-1 |
| MW: | 416.64 D |
From 138.00€
*
Hispidulin
Item number: TGM-TQ0201-10mg
Description: Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 µM). Target: Pim. Smiles: COc1c(O)cc2oc(cc(=O)c2c1O)-c1ccc(O)cc1. References: Chao SW, et al. Total Synthesis of Hispidulin and the Structural Basis for Its Inhibition of Proto-oncogene...
| Keywords: | Dinatin |
| CAS | 1447-88-7 |
| MW: | 300.26 D |
From 52.00€
*
Epothilone D
Item number: TGM-TQ0202-100mg
Description: Epothilone D (KOS 862) is a potent microtubule stabilizer. Target: Microtubule Associated. Smiles: C[C@H]1CCC\C(C)=C/C[C@H](OC(=O)C[C@H](O)C(C)(C)C(=O)[C@H](C)[C@H]1O)C(\C)=C\c1csc(C)n1. References: Konner J, et al. Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D)...
| Keywords: | KOS 862 |
| Application: | Microtubule-stabilizing agent, brain penetrant |
| CAS | 189453-10-9 |
| MW: | 491.68 D |
From 918.00€
*
Tafluprost
Item number: TGM-TQ0203-100mg
Description: Tafluprost, a prostaglandin analog, is the selective agonist of fluoroprostaglandin (FP) receptor PGF2alpha. Target: Others, Prostaglandin Receptor. Smiles: CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\C(F)(F)COc1ccccc1. References: Kuwayama, Y. and A. Nomura, Prospective observational...
| Keywords: | MK2452 , AFP-168 |
| Application: | Targets prostaglandin F receptor (PTGFR) |
| CAS | 209860-87-7 |
| MW: | 452.53 D |
From 32.00€
*
Cefozopran
Item number: TGM-TQ0204-25mg
Description: Cefozopran is a fourth-generation cephalosporin. Target: Antibiotic. Smiles: [H][C@]12SCC(C[n+]3ccn4ncccc34)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1nsc(N)n1)C([O-])=O , c:16,
| Keywords: | SCE-2787 |
| Application: | Antibacterial, Cell wall biosynthesis inhibitor |
| CAS | 113359-04-9 |
| MW: | 515.52 D |
Please request pricing for this article.
Ailanthone
Item number: TGM-TQ0209-10mg
Description: Ailanthone (Delta13-Dehydrochaparrinone) is an effective inhibitor of both full-length androgen receptor (AR) (IC50: 69 nM) and constitutively active truncated AR splice variants (IC50: 309 nM). Target: Androgen Receptor. Smiles:...
| Keywords: | Delta13-Dehydrochaparrinone |
| CAS | 981-15-7 |
| MW: | 376.4 D |
From 35.00€
*
Savolitinib
Item number: TGM-TQ0210-100mg
Description: Savolitinib (Volitinib) (AZD-6094) is an effective, selective, and orally bioavailable c-Met inhibitor (IC50s: 5 nM/3 nM for c-Met/p-Met). Target: c-Met/HGFR. Smiles: C[C@@H](c1ccc2nccn2c1)n1nnc2ncc(nc12)-c1cnn(C)c1. References: Jia H, et al. Discovery of...
| Keywords: | Volitinib, AZD-6094, HMPL-504 |
| Application: | Targets proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (MET, HGFR) |
| CAS | 1313725-88-0 |
| MW: | 345.36 D |
From 40.00€
*
Brusatol
Item number: TGM-TQ0211-100mg
Description: Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2. Target: Apoptosis, Ferroptosis, Nrf2. Smiles: COC(=O)[C@]12OC[C@@]34[C@H]1[C@@H](OC(=O)C=C(C)C)C(=O)O[C@@H]3C[C@H]1C(C)=C(O)C(=O)C[C@]1(C)[C@H]4[C@@H](O)[C@@H]2O. References: Wang Y, Ma H, Huang J, et...
| Keywords: | (+)-Brusatol , NSC 172924 |
| CAS | 14907-98-3 |
| MW: | 520.53 D |
From 32.00€
*
Bruceantin
Item number: TGM-TQ0213-10mg
Description: Bruceantin (NSC-165563) is a natural product isolated from Brucea antidysenterica. Bruceantin has antitumor activity against B16 melanoma, colon 38, and L1210 and P388 leukemia in mice. Target: Others. Smiles:...
| Keywords: | NSC165563, (-)-Bruceantin, NCI165563 |
| CAS | 41451-75-6 |
| MW: | 548.58 D |
From 101.00€
*
Ercalcitriol
Item number: TGM-TQ0216-10mg
Description: Ercalcitriol (1alpha,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2 that strengthens immunity by regulating cathelicidin antimicrobial peptide (CAMP) and defensin beta-4 (DEFB4) genes in normal and transformed cells, combating pathogenic infections. Target: Others. Smiles:...
| Keywords: | 1alpha,25-Dihydroxy Vitamin D2 |
| Application: | Metabolic studies |
| CAS | 60133-18-8 |
| MW: | 428.65 D |
From 91.00€
*
Gomisin G
Item number: TGM-TQ0217-10mg
Description: Gomisin G is a natural compound and exhibits potent anti-HIV activity (EC50: 0.006 µg/mL, therapeutic index: 300). It is a good substrate of CYP2C9. Target: P450, HIV Protease. Smiles: COc1cc2C[C@H](C)[C@](C)(O)[C@@H](OC(=O)c3ccccc3)c3cc4OCOc4c(OC)c3-c2c(OC)c1OC. References: Chen DF, et al. Anti-AIDS...
| CAS | 62956-48-3 |
| MW: | 536.57 D |
From 60.00€
*