Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Hydrastine
Item number: TGM-TQ0160-10mg
Description: Hydrastine ((-)-beta-Hydrastine) is a natural alkaloid that is present in Hydrastis Canadensis. Target: Others. Smiles: [H][C@@]1(OC(=O)c2c1ccc(OC)c2OC)[C@]1([H])N(C)CCc2cc3OCOc3cc12
| Keywords: | (-)-beta-Hydrastine, (1R,9S)-beta-Hydrastine |
| Application: | Tyrosine hydroxylase inhibitor |
| CAS | 118-08-1 |
| MW: | 383.39 D |
From 31.00€
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Mulberrin
Item number: TGM-TQ0161-100mg
Description: Mulberrin (Kuwanon C) is an inhibitor of OATP2B1-mediated estrone-3-sulfate (E3S) uptake (IC50: 1.8 ±1.5 µM). Target: Others. Smiles: CC(C)=CCc1c(O)cc(O)c2c1oc(-c1ccc(O)cc1O)c(CC=C(C)C)c2=O. References: Wen F, et al. Identification of natural products as modulators of OATP2B1 using LC-MS/MS to quantify...
| Keywords: | Kuwanon C |
| CAS | 62949-79-5 |
| MW: | 422.47 D |
From 52.00€
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R-1479
Item number: TGM-TQ0162-100mg
Description: R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 µM for HCV RNA replication in the HCV subgenomic replicon system. Target: HCV Protease. Smiles: Nc1ccn([C@@H]2O[C@@](CO)(N=[N+]=[N-])[C@@H](O)[C@H]2O)c(=O)n1. References: Klumpp K, et al. The novel nucleoside analog R1479...
| Keywords: | 4'-Azidocytidine |
| CAS | 478182-28-4 |
| MW: | 284.23 D |
From 129.00€
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Dodecanoic acid ingenol ester
Item number: TGM-TQ0164-1mg
Description: Dodecanoic acid ingenol ester, a natural compound, shows moderate cytotoxicity with IC50 values being 35.59 µM (Caco-2), 24.04 µM (MCF-7), and 22.24 µM (MCF-7/ADM). Target: Others. Smiles: [H][C@]12[C@]3([H])C=C(CO)[C@@H](O)[C@]4(O)[C@@H](O)C(C)=C[C@]4([C@H](C)C[C@@]1(OC(=O)CCCCCCCCCCC)C2(C)C)C3=O....
| Keywords: | 13-Oxyingenol dodecanoat |
| CAS | 54706-70-6 |
| MW: | 546.745 D |
471.00€
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Arglabin
Item number: TGM-TQ0165-100mg
Description: Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects. Target: Transferase, NOD, NOD-like Receptor (NLR), Autophagy. Smiles: [H][C@@]12CC[C@]3(C)O[C@@]33CC=C(C)[C@]3([H])[C@@]1([H])OC(=O)C2=C....
| Keywords: | (+)-Arglabin |
| Application: | Anticancer compound, Farnesyltransferase inhibitor |
| CAS | 84692-91-1 |
| MW: | 246.3 D |
From 100.00€
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Tesevatinib
Item number: TGM-TQ0166-10mg
Description: Tesevatinib (XL-647) is an orally available, multi-target tyrosine kinase inhibitor (IC50s: 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, Flt4, and EphB4). Target: VEGFR, Ephrin Receptor, EGFR, FLT. Smiles: COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(C)C[C@H]2C1. References: Gendreau...
| Keywords: | EXEL-7647, XL-647, KD-019 |
| Application: | Targets epidermal growth factor receptor [EC:2.7.10.1] (EGFR, ERBB1) |
| CAS | 781613-23-8 |
| MW: | 491.39 D |
From 103.00€
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Desacetylcinobufagin
Item number: TGM-TQ0170-10mg
Description: Desacetylcinobufagin (Deacetylcinobufagin) , a natural product, shows potent activities against Hela and A375 cells in vitro. Target: Others. Smiles: [H][C@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@H]([C@@H](O)[C@H]5O[C@@]345)c3ccc(=O)oc3)[C@@]1(C)CC[C@H](O)C2. References: Xiao-Chi Ma, et al. Efficient...
| Keywords: | Deacetylcinobufagin |
| CAS | 4026-95-3 |
| MW: | 400.51 D |
From 39.00€
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Isoastragaloside I
Item number: TGM-TQ0171-100mg
Description: Isoastragaloside I is a natural product,has the enhancement adiponectin quantity activity. Target: Others. Smiles:...
| CAS | 84676-88-0 |
| MW: | 869.04 D |
From 44.00€
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2''-O-Rhamnosylicariside II
Item number: TGM-TQ0172-10mg
Description: 2''-O-Rhamnosylicariside II is beneficial for improving postmenopausal osteoporosis and demonstrates potent antioxidant activity, with IC50 values of 90.5 µM [90.5 uM]. Target: Others. Smiles:...
| CAS | 135293-13-9 |
| MW: | 660.66 D |
From 90.00€
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Mavorixafor
Item number: TGM-TQ0174-100mg
Description: Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC50 = 1 nM) and PBMCs (IC50 = 9 nM). Target: CXCR. Smiles:...
| Keywords: | AMD-070 |
| Application: | Targets C-X-C chemokine receptor type 4 (CXCR4, CD184) |
| CAS | 558447-26-0 |
| MW: | 349.47 D |
From 34.00€
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Dexpramipexole
Item number: TGM-TQ0175-5mg
Description: Dexpramipexole (KNS-760704, R-(+)-Pramipexole) is a neuroprotective agent and weak non-ergoline dopamine agonist. Target: Dopamine Receptor. Smiles: CCCN[C@@H]1CCc2nc(N)sc2C1. References: Alavian KN, Dworetzky SI, Bonanni L, et al. Effects of dexpramipexole on brain mitochondrial conductances and...
| Keywords: | KNS-760704, (R)-Pramipexole, R-(+)-Pramipexole |
| Application: | Dopamine receptor agonist |
| CAS | 104632-28-2 |
| MW: | 211.33 D |
42.00€
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(-)-Isocorypalmine
Item number: TGM-TQ0176-10mg
Description: (-)-Isocorypalmine ((S)-Tetrahydrocolumbamine), a natural product isolated from Corydalis chaerophylla, has significant antifungal activity. Target: Antifungal, Dopamine Receptor. Smiles: [H][C@@]12Cc3ccc(OC)c(OC)c3CN1CCc1cc(OC)c(O)cc21. References: Sangita Sahni, et al. Inhibitory Effect of Two...
| Keywords: | Tetrahydrocolumbamine , (S)-Tetrahydrocolumbamine |
| MW: | 341.4 D |
From 68.00€
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