Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys
Item number: TGM-TQ0143-100mg
Description: N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA is a formyl peptide receptor (FPR) agonist. Target: Others. Smiles: CCCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCC)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(O)=O
| Keywords: | For-Nle-Leu-Phe-Nle-Tyr-Lys-OH |
| CAS | 71901-21-8 |
| MW: | 824.02 D |
From 62.00€
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Ac-DEVD-CHO
Item number: TGM-TQ0146-10mg
Description: Ac-DEVD-CHO is a specific Caspase-3 inhibitor (Ki: 230 pM) with inhibitory effects on SLNT-induced apoptosis. Target: Caspase, Apoptosis. Smiles: [H][C@@](CC(O)=O)(NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCC(O)=O)NC(=O)[C@]([H])(CC(O)=O)NC(C)=O)C(C)C)C=O. References: Garcia-Calvo M, et al.nhibition of human...
| Application: | Caspase-3 (ICE) inhibitor |
| CAS | 169332-60-9 |
| MW: | 502.47 D |
From 56.00€
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Ac-DEVD-CHO acetate
Item number: TGM-TQ0146L-10mg
Description: Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3. Target: Caspase. Smiles: CC(O)=O.CC(C)[C@@H](C(NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)N)=O)=O)=O)N(C(C)=O)[C@H](C=O)CC(O)=O. References: Wang J , Li W , Xiao H , et al. A polysaccharide from Lentinus edodes inhibits...
| Keywords: | Caspase-3 Inhibitor I, Ac-DEVD-CHO acetate (169332-60-9 free base), N-acetyl-asp-glu-val-asp-al |
| MW: | 562.52 D |
From 67.00€
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Arundic Acid
Item number: TGM-TQ0147-10mg
Description: Arundic Acid (ONO 2506) is an astrocyte-modulating agent, delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100beta synthesis. Target: Others. Smiles: CCCCCC[C@@H](CCC)C(O)=O. References: Tomoyuki Hasegawa, et al. Process Development of...
| Keywords: | ONO 2506, (R)-2-Propyloctanoic acid |
| Application: | Nootropic, Neuroprotectant |
| CAS | 185517-21-9 |
| MW: | 186.29 D |
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Orotidine
Item number: TGM-TQ0148-5mg
Description: Orotidine (Uridin-6-carboxylic acid) is a nucleoside found in bacteria, fungi, and plants. In humans, orotidine occurs as its 5'-phosphate (orotidylic acid). Target: Endogenous Metabolite. Smiles: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1c(cc(=O)[nH]c1=O)C(O)=O. References: A M MICHELSON, et al. A new ribose...
| Keywords: | 6-Carboxyuridine, Uridin-6-carboxylic acid |
| CAS | 314-50-1 |
| MW: | 288.21 D |
787.00€
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Levcromakalim
Item number: TGM-TQ0150-100mg
Description: Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel. Target: Potassium Channel. Smiles: CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)N1CCCC1=O)C#N. References: Matsumoto T, et al. Tunicamycin-Induced Alterations in the Vasorelaxant Response in Organ-Cultured Superior Mesenteric Arteries of Rats....
| Keywords: | BRL 38227, (-)-Cromakalim |
| Application: | Antiasthmatic, Antihypertensive |
| CAS | 94535-50-9 |
| MW: | 286.33 D |
From 46.00€
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L-655708
Item number: TGM-TQ0151-10mg
Description: L-655708 is a selective and highly potent GABAA receptor reverse agonist with a Ki value of 0.45 nM. Target: GABA Receptor. Smiles: [H][C@@]12CCCN1C(=O)c1cc(OC)ccc1-n1cnc(C(=O)OCC)c21. References: Saab BJ, et al. Short-term memory impairment after isoflurane in mice is prevented by the alpha5...
| Application: | Nootropic GABA(A) receptor subunit alpha-5 ligand |
| CAS | 130477-52-0 |
| MW: | 341.36 D |
From 73.00€
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Dalfopristin
Item number: TGM-TQ0152-100mg
Description: Dalfopristin (RP54476) is a semi-synthetic streptogramin antibiotic. Quinupristin/Dalfopristin (Q/D) is used for the treatment of multi-drug resistant Enterococcus faecium infections. Target: Antibacterial, Antibiotic. Smiles:...
| Keywords: | RP54476 |
| Application: | Antibacterial |
| CAS | 112362-50-2 |
| MW: | 690.85 D |
From 179.00€
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Mibefradil
Item number: TGM-TQ0153-100mg
Description: Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 µM and 18.6 µM for T-type and L-type currents). Target: Calcium Channel. Smiles: C(CN(CCCC=1NC=2C(N1)=CC=CC2)C)[C@]3(OC(COC)=O)[C@@H]([C@@H](C)C)C=4C(CC3)=CC(F)=CC4. References: Mehrke G, et al. The...
| Keywords: | Ro 40-5967 |
| Application: | Vasodilator, Calcium channel blocker |
| CAS | 116644-53-2 |
| MW: | 495.63 D |
From 2,295.00€
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GW1929
Item number: TGM-TQ0156-100mg
Description: GW1929 is a potent PPAR-gamma agonist (pKi: 8.84 for human PPAR-gamma, pEC50s of 8.56 and 8.27 for human and murine PPAR-gamma). Target: PPAR. Smiles: CN(CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(O)=O)cc1)c1ccccn1. References: Brown KK, et al. A novel N-aryl tyrosine activator of peroxisome...
| Application: | PPARgamma agonist, Angiogenesis inhibitor, Apoptosis inhibitor |
| CAS | 196808-24-9 |
| MW: | 495.57 D |
From 30.00€
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EIPA
Item number: TGM-TQ0157-10mg
Description: EIPA (L593754) is a TRPP3 channel inhibitor (IC50=10.5 µM) and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy, and can be used in inflammation and tumor studies. Target: Prostaglandin Receptor, COX, TRP/TRPV Channel, Autophagy, Sodium Channel. Smiles:...
| Keywords: | L593754 , MH 12-43 |
| MW: | 299.76 D |
From 30.00€
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Azaserine
Item number: TGM-TQ0158-10mg
Description: Azaserine (CI-337) is a tumor-inhibiting antibiotic isolated from a species of Streptomyces and functions as an inhibitor of glutamine amidotransferase. Target: Antibiotic, Others. Smiles: N[C@@H](COC(=O)C=[N+]=[N-])C(O)=O. References: Wise DR, et al. Glutamine addiction: a new therapeutic target in...
| Keywords: | O-Diazoacetyl-L-serine, CI-337, P-165 |
| MW: | 173.13 D |
From 30.00€
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