Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
No results were found for the filter!
AGN 193109
Item number: TGM-TQ0097-100mg
Description: AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARalpha, RARbeta, and RARgamma). Target: Autophagy, Retinoid Receptor. Smiles: Cc1ccc(cc1)C1=CCC(C)(C)c2ccc(cc12)C#Cc1ccc(cc1)C(O)=O. References: Johnson AT, et al. Synthesis and characterization...
| CAS | 171746-21-7 |
| MW: | 392.49 D |
From 58.00€
*
Quiflapon sodium
Item number: TGM-TQ0098-100mg
Description: Quiflapon sodium (MK591) is a selective inhibitor of 5-Lipoxygenase-activating protein (FLAP). Target: FLAP. Smiles: [Na].CC(C)(C)Sc1c(CC(C)(C)C(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc12. References: Mendis C, et al. Effect of 5-lipoxygenase inhibitor MK591 on early molecular and signaling events...
| Keywords: | MK591 |
| Application: | Targets arachidonate 5-lipoxygenase-activating protein (ALOX5AP, FLAP) |
| CAS | 147030-01-1 |
| MW: | 610.16 D |
From 80.00€
*
20-O-Acetylingenol-3-angelate
Item number: TGM-TQ0099-100mg
Description: 20-O-Acetylingenol-3-angelate (Euphorbia factor Pe1) is a natural compound found in the leaves and stems of the plant Inga. It has a variety of biological activities including tumor growth inhibition, anti-inflammatory, antifungal and antioxidant effects. Target: Others. Smiles:...
| Keywords: | Euphorbia factor Pe1 |
| MW: | 472.57 D |
From 161.00€
*
AZ505
Item number: TGM-TQ0100-100mg
Description: AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 µM). Target: Histone Methyltransferase. Smiles: Oc1ccc(CCNCCN(C2CCCCC2)C(=O)CCNCCc2ccc(Cl)c(Cl)c2)c2OCC(=O)Nc12. References: Komatsu S, et al. Overexpression of SMYD2 contributes to malignant outcome in gastric cancer. Br J Cancer. 2015 Jan...
| Application: | SMYD2 inhibitor |
| CAS | 1035227-43-0 |
| MW: | 577.54 D |
From 55.00€
*
MKC3946
Item number: TGM-TQ0101-100mg
Description: MKC3946 is an effective and soluble IRE1alpha inhibitor which triggered modest growth inhibition in multiple myeloma cell lines. Target: IRE1. Smiles: CN1CCN(CC1)C(=O)c1ccc(s1)-c1ccc2c(C=O)c(O)ccc2c1. References: Zhang L, et al. IRE1 inhibition perturbs the unfolded protein response in a pancreatic...
| Application: | IRE1alpha inhibitor |
| CAS | 1093119-54-0 |
| MW: | 380.46 D |
From 57.00€
*
Theviridoside
Item number: TGM-TQ0102-5mg
Description: Theviridoside is a natural product found in the leaves of Cerbera odollam. Target: Others. Smiles: O[C@]12[C@]([C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C1C(OC)=O)(C(CO)=CC2)[H]. References: Gorantla JN, et al. Cytotoxicity studies of semi-synthetic derivatives of theveside derived from the...
| CAS | 23407-76-3 |
| MW: | 404.37 D |
1,362.00€
*
INCB3344
Item number: TGM-TQ0103-100mg
Description: INCB3344 is an effective, specific and orally bioavailable CCR2 antagonist with IC50 values of 9.5 nM (mCCR2) and 5.1 nM (hCCR2) in binding antagonism and 7.8 nM (mCCR2) and in 3.8 nM (hCCR2) antagonism of chemotaxis activity. Target: CCR. Smiles:...
| Application: | CCR2 antagonist |
| CAS | 1262238-11-8 |
| MW: | 577.59 D |
From 60.00€
*
CRT0066101 dihydrochloride
Item number: TGM-TQ0104-10mg
Description: CRT0066101 dihydrochloride is an effective and selective PKD inhibitor (IC50s: 1, 2.5 and 2 nM for PKD1, 2, and 3). Target: Serine/threonin kinase. Smiles: Cl.Cl.CC[C@@H](N)CNc1ccnc(n1)-c1cc(ccc1O)-c1cnn(C)c1. References: Harikumar KB, et al. A novel small-molecule inhibitor of protein kinase D blocks...
| CAS | 1883545-60-5 |
| MW: | 411.33 D |
From 30.00€
*
CAY10650
Item number: TGM-TQ0105-100mg
Description: CAY10650 is an effective inhibitor of cytosolic phospholipase A2alpha (cPLA2alpha, IC50: 12 nM). Target: Phospholipase. Smiles: CC(C)C(=O)c1cn(CC(=O)COc2ccc(Oc3ccccc3)cc2)c2ccc(cc12)C(O)=O. References: Tripathi T, et al. Role of phospholipase A 2(PLA2) inhibitors in attenuating apoptosis of the corneal...
| CAS | 1233706-88-1 |
| MW: | 471.5 D |
From 45.00€
*
Sacubitrilat
Item number: TGM-TQ0106-100mg
Description: Sacubitrilat (LBQ-657) (LBQ657) is an effective inhibitor of active neprilysin (NEP). Target: Neprilysin. Smiles: C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)CCC(O)=O)C(O)=O. References: Schiering N, et al. Structure of neprilysin in complex with the active metabolite of sacubitril. Sci Rep. 2016 Jun...
| Keywords: | LBQ-657 |
| Application: | Neprilysin inhibitor |
| CAS | 149709-44-4 |
| MW: | 383.44 D |
From 39.00€
*
MK-6892
Item number: TGM-TQ0108-100mg
Description: MK-6892 is a selective and full agonist for the high-affinity nicotinic acid receptor GPR109A (Ki: 4 nM, GTPgammaS EC50: 16 nM). Target: GPCR. Smiles: CC(C)(Cc1nc(no1)-c1ccc(O)cn1)C(=O)NC1=C(CCCC1)C(O)=O. References: Shen HC, et al. Discovery of a biaryl cyclohexene carboxylic acid (MK-6892): a potent...
| CAS | 917910-45-3 |
| MW: | 386.4 D |
From 83.00€
*
ROCK-IN-2
Item number: TGM-TQ0110-100mg
Description: ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2. Target: ROCK. Smiles: Cc1c[nH]c2nccc(Oc3c(F)cc(Nc4cc(Cl)nc(N)n4)cc3F)c12. References: Kast R, et al. Cardiovascular effects of a novel potent and highly selective...
| Keywords: | Azaindole 1, TC-S 7001 |
| Application: | ROCK inhibitor |
| CAS | 867017-68-3 |
| MW: | 402.79 D |
From 109.00€
*