Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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N-Succinimidyl-S-acetylthioacetate
Item number: TGM-T16251-500mg
Description: N-Succinimidyl-S-acetylthioacetate (SATA) is a protein modification agent that introduces thiol-groups into protein molecules and adds sulfhydryl groups in a protected form to proteins and other amine-containing molecules for later reaction with sulfhydryl reactive crosslinkers such as Sulfo-SMCC,...
| Keywords: | SATA |
| CAS | 76931-93-6 |
| MW: | 231.23 D |
From 30.00€
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Y-27632 dihydrochloride
Item number: TGM-T1725-10mg
Description: Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells. Target: Apoptosis, ROCK. Smiles: Cl.Cl.C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc1ccncc1....
| Keywords: | Y-27632 2HCl |
| Application: | ROCK kinase inhibitor |
| CAS | 129830-38-2 |
| MW: | 320.26 D |
From 32.00€
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Ambrisentan
Item number: TGM-T1655-5mg
Description: Ambrisentan (BSF 208075) is an endothelin receptor antagonist used in the therapy of pulmonary arterial hypertension (PAH). Ambrisentan has been associated with a low rate of serum enzyme elevations during therapy but has yet to be implicated in cases of clinically apparent acute liver injury. Target:...
| Keywords: | BSF 208075, BSF-208075, LU 208075 |
| Application: | Targets endothelin receptor type A (EDNRA) |
| CAS | 177036-94-1 |
| MW: | 378.42 D |
From 30.00€
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SBE-beta-CD
Item number: TGM-T16858-1g
Description: SBE-beta-CD (Sulfobutylether-beta-Cyclodextrin) is a beta-cyclodextrin derivative with a sodium sulfonate salt separated from the lipophilic cavity by a butyl ether spacer group, or sulfobutylether. SBE-beta-CD is widely used as a co-solvent in biological experiments. Target: Others. References: Sharp...
| Keywords: | Sulfobutylether-beta-Cyclodextrin |
| CAS | 182410-00-0 |
From 39.00€
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Liafensine
Item number: TGM-T32737-5mg
Description: Liafensine(BMS-820836) is a novel and selective triple monoamine reuptake inhibitor with inhibitory effects on the reuptake of serotonin, norepinephrine, and dopamine for the study of major depressive disorder and central nervous system disorders. Target: Norepinephrine, 5-HT Receptor, Dopamine...
| Keywords: | BMS-820836, DB104, BMS820836, BMS 820836 |
| Application: | Targets solute carrier family 6 (neurotransmitter transporter, serotonin) member 4 (SLC6A4, SERT) |
| CAS | 1198790-53-2 |
| MW: | 366.46 D |
From 365.00€
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Emodin
Item number: TGM-T2869-50mg
Description: Emodin (Frangula emodin) is a naturally occurring anthraquinone present in the roots and barks of numerous plants, exerts antiproliferative effects in Y cells that are regulated by different signaling pathways. Target: Autophagy, SARS-CoV, Casein Kinase. Smiles:...
| Keywords: | Frangula emodin |
| Application: | p56lck protein kinase inhibitor |
| CAS | 518-82-1 |
| MW: | 270.24 D |
From 43.00€
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Aloe emodin
Item number: TGM-T2843-20mg
Description: Aloe emodin (Rhabarberone) is an interferon-inducing agent, for JEV (IC50=1 µg/mL) and EV71(IC50=0.33 µg/mL ). Target: HSV, Autophagy. Smiles: O=C1C=2C(C(=O)C=3C1=CC=CC3O)=C(O)C=C(CO)C2. References: Li SW, et al. Eur J Pharmacol. 2014 Sep 5,738:125-32.
| Keywords: | NSC 38628, 3-Hydroxymethylchrysazine, Rhabarberone, Aloe-emodin |
| CAS | 481-72-1 |
| MW: | 270.24 D |
33.00€
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CCCP
Item number: TGM-T7081-100mg
Description: CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. CCCP inhibits the activation of STING and its downstream signaling molecules TBK1 and IRF3. Target: Mitochondrial Metabolism, COX, IkappaB/IKK, Apoptosis,...
| Keywords: | Carbonyl Cyanide m-Chlorophenylhydrazone, Carbonyl cyanide 3-chlorophenylhydrazone |
| CAS | 555-60-2 |
| MW: | 204.62 D |
From 39.00€
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TGF beta 1 Protein, Mouse/Rat, Recombinant
Item number: TGM-TMPJ-00771-10ug
Description: Transforming growth factor beta 1 (TGFbeta1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth,...
| Keywords: | transforming growth factor beta-1, transforming growth factor beta-1, TGF-beta1, TGFB1, TGFbeta, TGF-beta-1,... |
| MW: | 13 kD |
From 172.00€
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CP-91149
Item number: TGM-T6455-5mg
Description: CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 µM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose. Target: Phosphorylase. Smiles: CN(C)C(=O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1. References: Martin WH, et al. Proc Natl Acad...
| Application: | Glycogen phosphorylase inhibitor |
| CAS | 186392-40-5 |
| MW: | 399.87 D |
From 45.00€
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5-Fluorouracil
Item number: TGM-T0984-1g
Description: 5-Fluorouracil (5-FU) is a uracil analog and inhibitor of DNA synthesis, exhibiting antitumor activity by affecting pyrimidine synthesis through thymidylate synthase inhibition, it induces apoptosis and autophagy. Target: Endogenous Metabolite, HIV Protease, Apoptosis, DNA/RNA Synthesis, Nucleoside...
| Keywords: | NSC 19893, 5-Fluoracil, Fluorouracil, 5-FU |
| CAS | 51-21-8 |
| MW: | 130.08 D |
From 30.00€
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Q-VD-OPH
Item number: TGM-T0282-5mg
Description: Q-VD-OPH (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a pan-caspase inhibitor with potent antiapoptotic properties. Target: Caspase, HIV Protease. Smiles: CC(C)[C@H](NC(=O)c1ccc2ccccc2n1)C(=O)N[C@@H](CC(O)=O)C(=O)COc1c(F)cccc1F. References: Mischak R. ICN Bioconcepts. 2002, 8, 1-5.
| Keywords: | Quinoline-Val-Asp-Difluorophenoxymethylketone |
| CAS | 1135695-98-5 |
| MW: | 513.5 D |
From 45.00€
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