Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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p53 Activator 14
Item number: TGM-T204386-10mg
Description: p53 Activator 14 (Compound 7A) is a derivative of Neratinib that can induce DNA damage and activate p53, thereby inhibiting the proliferation of various cancer cells, with an IC50 of 7.21 µM for HCT116 cells. This compound hinders adhesion, migration, and invasion of HCT116 cells, disrupts the cell...
| MW: | 505.008 D |
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4-CAB hydrochloride
Item number: TGM-T204392-10mg
Description: 4-CAB hydrochloride is an analog of p-chlorophenylisopropylamine, serving as a psychoactive compound that inhibits the reuptake of serotonin (IC50 = 330 nM) and dopamine (IC50 = 2.3 µM). Target: 5-HT Receptor. Smiles: Cl.ClC1=CC=C(C=C1)CC(N)CC
| MW: | 220.139 D |
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MTDH-SND1 blocker 2
Item number: TGM-T204399-10mg
Description: MTDH-SND1 blocker 2 (compound C19) is an effective MTDH-SND1 inhibitor with an IC50 value of 487 nM. It binds to the SND1 protein with a Kd of 279 nM and can degrade the SND1 protein. Additionally, MTDH-SND1 blocker 2 exhibits antiproliferative activity and induces apoptosis, showing potential for...
| MW: | 353.37 D |
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Sulfo Cy3 bis NHS ester
Item number: TGM-T204402-10mg
Description: Sulfo Cy3 bis NHS ester is a derivative of Cy3 dye containing sulfonate ions. It is utilized for labeling proteins, amine-modified oligonucleotides, and other primary amine (R-NH2) containing molecules. Smiles:...
| MW: | 904.934 D |
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Cy7 maleimide
Item number: TGM-T204405-10mg
Description: Cy7 maleimide is a fluorescent dye containing a maleimide functional group. The maleimide group is suitable for labeling thiol groups on antibodies, proteins, and peptides. Smiles: CC1(C2=CC=CC=C2[N+](=C1/C=C/C=C/C=C/C=C/3\C(C4=CC=CC=C4N3CCCCCC(=O)NCCN5C(=O)C=CC5=O)(C)C)C)C.[Cl-]
| MW: | 667.279 D |
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RORgamma-IN-2
Item number: TGM-T204411-10mg
Description: RORgamma-IN-2 (Compound 22) is an inhibitor of RORgamma, with a Ki value of 16.6 nM for hRORgamma. It is useful for research in IL-17-dependent autoimmune diseases. Target: ROR. Smiles: C(NCC1=CC=C(S(CC)(=O)=O)C=N1)(=O)C=2SC=3C4(CCN([C@H](C)C=5C=NC(C(F)(F)F)=NC5)CC4)O[C@@H](C)CC3C2
| MW: | 623.71 D |
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FPMINT
Item number: TGM-T204414-10mg
Description: FPMINT is a potent, irreversible, and non-competitive inhibitor of equilibrative nucleoside transporters (ENTs), with a higher selectivity for ENT2 compared to ENT1. It plays a significant role in the uptake of uridine. Smiles: FC=1C=CC=CC1N2CCN(CC=3N=C(N=C(N3)NC4=CC=CC=5C=CC=CC54)N)CC2
| MW: | 429.493 D |
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PSF-IN-1
Item number: TGM-T204428-10mg
Description: PSF-IN-1 (Compound No.10-3) is an inhibitor of the RNA-binding protein (PSF), effectively blocking PSF-RNA interactions with an IC50 of 2.2 pM. It enhances histone acetylation, suppresses tumor cell proliferation, and induces apoptosis. PSF-IN-1 exhibits antitumor activity. Target: Apoptosis. Smiles:...
| MW: | 284.263 D |
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ATIC-IN-2
Item number: TGM-T204433-10mg
Description: ATIC-IN-2 (Compound 1) is a competitive inhibitor of the bifunctional enzyme AICAR Tfase/IMPCH (ATIC), binding to inosine monophosphate cyclohydrolase (IMPCH) with a Ki of 0.13 µM. Target: DNA/RNA Synthesis. Smiles: O=C1NS(=O)(=O)NC=2N=CNC12
| MW: | 188.165 D |
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CY7 DBCO chloride
Item number: TGM-T204435-10mg
Description: CY7 DBCO chloride is a dye derivative of CY7 containing a DBCO group. This compound acts as a click chemistry reagent, featuring a DBCO group that enables it to engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules bearing an Azide group. Smiles:...
| MW: | 803.472 D |
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DL-Thyroxine
Item number: TGM-T204436-10mg
Description: DL-Thyroxine is a thyroid hormone that acts as a monoamine oxidase (monoamine oxidase) inhibitor. Target: Monoamine Oxidase. Smiles: O=C(O)C(N)CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1
| MW: | 776.87 D |
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human TDO2-IN-1
Item number: TGM-T204437-10mg
Description: Human TDO2-IN-1 (Cpd-2) is a potent inhibitor of human TDO2, with an IC50 of 14.8 nM. It plays a significant role in studies related to metabolism, inflammation, and tumor immune surveillance. Target: IDO, Indoleamine 2,3-Dioxygenase (IDO). Smiles:...
| MW: | 532.631 D |
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