Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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CK1delta-IN-3
Item number: TGM-T204344-100mg
Description: CK1delta-IN-3 (compound 376) is a CK1delta (casein kinase 1delta) inhibitor that can be used to study neurodegenerative diseases such as Alzheimer's disease. Target: Casein Kinase. Smiles: N#CC1=CC=C(C=C1)CSC2=NC=3C=CC=CC3C(=O)N2C4=CC=C(OCC)C=C4
| MW: | 413.49 D |
From 183.00€
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Ferroptosis-IN-17
Item number: TGM-T204345-10mg
Description: Ferroptosis-IN-17 (Compound 18) is an inhibitor of ferroptosis with an EC50 value of 0.57 µM. It effectively reduces the accumulation of intracellular ferrous ions and lipid peroxidation while restoring levels of glutathione (GSH) and glutathione peroxidase 4 (GPX4). In rat plasma, Ferroptosis-IN-17...
| MW: | 446.52 D |
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SHO1122147
Item number: TGM-T204360-10mg
Description: SHO1122147 (Compound 7m) disrupts the mitochondrial electron transport chain, demonstrating mitochondrial uncoupling activity (EC50=3.6 µM). It increases the cellular oxygen consumption rate (OCR=69%) and enhances cellular respiration. Additionally, SHO1122147 is orally active and can be utilized in...
| MW: | 338.748 D |
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Methyl piperazine-2-carboxylate
Item number: TGM-T204361-10mg
Description: Methyl piperazine-2-carboxylate (compound 4) is a potent activator of METTL3/METTL14/WTAP. It enhances the production of HIV-1p24 viral particles and increases the level of N6-methyladenosine in the viral RNA genome. Target: HIV Protease. Smiles: O=C(OC)C1NCCNC1
| MW: | 144.172 D |
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Mcl-1 inhibitor 22
Item number: TGM-T204363-10mg
Description: Mcl-1 inhibitor22 (Example 36) is an MCL-1 inhibitor that suppresses its anti-apoptotic function by blocking the interaction between MCL-1 and pro-apoptotic proteins. It exhibits antiproliferative activity against various cancer cell lines and can be utilized for cancer research. Target: Apoptosis,...
| MW: | 590.084 D |
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Sulfo Cy7 bis-NHS ester
Item number: TGM-T204366-10mg
Description: Sulfo Cy7 bis-NHS ester is a derivative of a Cy7 dye containing sulfonate ions. It can be used to label proteins, amine-modified oligonucleotides, and other primary amine-containing (R-NH2) molecules. Smiles:...
| MW: | 957.009 D |
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Mutant IDH1-IN-3
Item number: TGM-T204372-10mg
Description: Mutant IDH1-IN-3 (Compound 1) is a selective allosteric inhibitor targeting the mutant isocitrate dehydrogenase 1 (IDH1), with an IC50 of 13 nM for R132HIDH1. It effectively suppresses the production of D-2-hydroxyglutarate (2HG) in cells and is applicable for research in oncology. Target: Isocitrate...
| MW: | 366.5 D |
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Org 274179-0
Item number: TGM-T204377-10mg
Description: Org 274179-0 is an effective allosteric antagonist of the thyroid-stimulating hormone (TSH) receptor, with an IC50 in the nanomolar range. It fully inhibits TSH (and TSI)-mediated activation of the TSH receptor with minimal impact on the efficacy of TSH. This compound can be utilized in studies of...
| MW: | 480.521 D |
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(-)-Mcl-1 inhibitor 22
Item number: TGM-T204378-10mg
Description: (-)-Mcl-1 inhibitor 22 (compound 38) is an agent that targets Mcl-1 and functions by blocking the interaction between Mcl-1 and pro-apoptotic proteins, thereby hindering Mcl-1's anti-apoptotic activity. It is applicable in cancer research. Target: Apoptosis, Bcl-2 Family. Smiles:...
| MW: | 590.084 D |
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Etripamil hydrochloride
Item number: TGM-T204379-10mg
Description: Etripamil (MSP-2017) hydrochloride is a fast-acting L-type calcium channel blocker used in the study of paroxysmal supraventricular tachycardia (PSVT). By inhibiting calcium ion influx through slow calcium channels, etripamil hydrochloride slows atrioventricular nodal conduction and extends the...
| Keywords: | (-)-MSP-2017 hydrochloride , Etripamil hydrochloride , MSP-2017 hydrochloride |
| MW: | 489.047 D |
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(S)-PF-04995274
Item number: TGM-T204390-10mg
Description: (S)-PF-04995274 is a partial agonist of the 5-hydroxytryptamine receptor 4 (5-HT4R) and is an isomer of PF-04995274. Target: 5-HT Receptor. Smiles: O(C1=C2C(OCC3CCN(CC4(O)CCOCC4)CC3)=NOC2=CC=C1)[C@H]5CCOC5
| MW: | 432.51 D |
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FGFR1 inhibitor-12
Item number: TGM-T204393-10mg
Description: FGFR1inhibitor-12 (compound 20) is an inhibitor of FGFR1 and is applicable in cancer research. Target: FGFR. Smiles: O=C1NC(C2=CC=C3C=C(OC)C=CC3=C2)(C(=O)N1CC4=CC=C(F)C=C4Cl)C
| MW: | 412.841 D |
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