Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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AD012
AD012

Item number: TGM-T62831-100mg

Description: AD012 is a dual inhibitor of cACE/NEP that utilizes the previously reported C-domain selective ACE inhibitor lenopril-tryptophan synthesis, potentially offering potent anti-hypertensive and cardioprotective effects. Target: Others
MW: 456.53 D
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Antitumor agent-54
Antitumor agent-54

Item number: TGM-T62835-100mg

Description: Antitumor agent-54 (Compound C11) is a 14-3-3eta protein inhibitor (KD: 35 µM). antitumor agent-54 inhibits several typical human hepatocellular carcinoma cell lines. antitumor agent-54 blocks the cell cycle in the G1-S phase and induces apoptosis, showing good metabolic stability. It exhibits good...
MW: 456.58 D
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Hit 1
Hit 1

Item number: TGM-T62836-100mg

Description: Hit 1, an activator of insulin-degrading enzymes (IDE) (EC50: 5.5 µM), reduces glucose-stimulated insulin secretion. Target: Others
MW: 456.58 D
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AR antagonist 4
AR antagonist 4

Item number: TGM-T62838-100mg

Description: AR antagonist 4 (Compound 67-b) is an orally active androgen receptor (AR) antagonist with an IC50 of 246.6 nM for wild-type AR. Target: Others
MW: 456.62 D
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5-HT1A antagonist 1
5-HT1A antagonist 1

Item number: TGM-T62843-100mg

Description: 5-HT1A antagonist 1 (compound 6f) is a potent and selective 5-HT1A receptor antagonist (Ki: 35 nM) and can be utilized in the study of central nervous system disorders. Target: Others
MW: 456.97 D
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Freselestat quarterhydrate
Freselestat quarterhydrate

Item number: TGM-T62846-100mg

Description: Freselestat quarterhydrate (ONO-6818 quarterhydrate) is a potent, orally active inhibitor of neutrophil elastase (Ki: 12.2 nM). The quarterhydrate is more than 100-fold less active against other proteases, including trypsin, proteinase 3, pancreatic elastase, thrombin, fibrin, collagenase, histone G,...
MW: 457.03 D
From 1,080.00€ *
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GSK2945 hydrochloride
GSK2945 hydrochloride

Item number: TGM-T62852-100mg

Description: GSK2945 hydrochloride is a tertiary amine and a highly specific antagonist of Rev-erbalpha/REV-ERBalpha (mouse/human reverse erythropoietic virus alpha) with an EC50 value of 21.5 µM and 20.8 µM, respectively.GSK2945 hydrochloride increases cholesterol 7alpha-hydroxylase ( The EC50 values were 21 µM and...
MW: 457.8 D
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K203
K203

Item number: TGM-T62857-100mg

Description: K203 is a potent tabun-inhibited AChE reactivator and is an important antidote to organophosphorus poisoning. Target: Others
MW: 458.15 D
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CK2-IN-3
CK2-IN-3

Item number: TGM-T62862-100mg

Description: CK2-IN-3 is a potent and selective CK2 inhibitor (Kd: 12 nM) with IC50 values of 1.51 µM for CK2alpha and 7.64 µM for CK2alpha'. CK2-IN-3 can be used in cancer research. Target: Others
MW: 458.46 D
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844-TFM
844-TFM

Item number: TGM-T62866-100mg

Description: 844-TFM is an NBTI (novel bacterial topoisomerase inhibitor) DNA gyrase inhibitor (IC50: 1.5 µM). 844-TFM exhibits bactericidal activity against Mycobacterium abscessus. Target: Others
MW: 458.48 D
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FABPs ligand 6
FABPs ligand 6

Item number: TGM-T62870-25mg

Description: FABPs ligand 6 (MF6) is an inhibitor of FABP5 (Kd: 874 nM) and FABP7 (Kd: 20 nM), and can be used in the study of multiple sclerosis. Target: Others
MW: 458.52 D
1,032.00€ *
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LRRK2-IN-6
LRRK2-IN-6

Item number: TGM-T62871-100mg

Description: LRRK2-IN-6 (compound 22) is an orally active, selective leucine-rich repeat protein kinase 2 (LRRK2) inhibitor with blood-brain barrier permeability, inhibiting GS LRRK2 (IC50: 4.6 µM) and WT LRRK2 (IC50: 49 µM). LRRK2-IN-6 exhibited inhibitory effects on the autophosphorylation of LRRK2 at Ser1292 and...
MW: 458.52 D
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12461 from 12462 pages