Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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PR 39 (porcine) acetate
Item number: TGM-TP1961L-10mg
Description: PR 39 (porcine) acetate is a noncompetitive, reversible and allosteric proteasome inhibitor. PR 39 (porcine) acetate reversibly binds to the alpha7 subunit of the proteasome and blocks degradation of NF-kappaB inhibitor IkappaBalpha by the ubiquitin-proteasome pathway. Target: Proteasome,...
From 186.00€
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Pseudo RACK1
Item number: TGM-TP1971-1mg
Description: Activator of protein kinase C, attached to cell permeabilization Antennapedia domain vector peptide. Consists of peptide derived from the C2 domain of PKC beta linked by a disulfide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or...
| MW: | 3198.81 D |
317.00€
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OD1
Item number: TGM-TP1972-1mg
Description: Potent rat Nav1.7, human Nav1.4 and rat Nav1.6 channel activator (EC50 values are 7, 10 and 47 nM, respectively). Exhibits minimal activation at mammalian Nav1.2, Nav1.3 and Nav1.5 (EC50 values >3 µM). Inhibits fast inactivation on all channels. Increases peak currents at all voltages and stimulates a...
| MW: | 7206.1 D |
1,257.00€
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Obtustatin
Item number: TGM-TP1974-1mg
Description: Highly potent integrin alpha1beta1 inhibitor (IC50 = 0.8 nM for alpha1beta1 binding to type IV collagen). Selective for alpha1beta1 over alpha2beta1, alphaIIbbeta3, alphavbeta3, alpha4beta1, alpha5beta6, alpha9beta1 and alpha4beta7. Inhibits FGF2-stimulated angiogenesis in the chicken chorioallantoic...
| MW: | 4393.07 D |
840.00€
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Oxyntomodulin acetate
Item number: TGM-TP1976L-100mg
Description: Oxyntomodulin acetate, a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist[1]. Target: Glucagon Receptor
From 174.00€
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NLS-StAx-h
Item number: TGM-TP1979-5mg
Description: Wnt inhibitor (IC50 = 1.4 µM). Stapled peptide inhibitor of oncogenic Wnt signaling. Inhibits beta-catenin-transcription factor interactions. Inhibits proliferation and migration of colorectal cancer cells. Cell permeable. References: Dietrich et al (2017) Cell permeable stapled peptide inhibitor of Wnt...
| MW: | 3445.26 D |
2,106.00€
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[Phe1Psi(CH2-NH)Gly2]Nociceptin(1-13)NH2
Item number: TGM-TP1988-1mg
Description: Potent agonist of the nociceptin (ORL1) receptor, demonstrated both in vitro and in vivo. Selective, competitive antagonism at the nociceptin receptor has also been reported (pA2 = 7.02 and 6.75 in the guinea pig ileum and mouse vas deferens respectively). References: Guerrini et al (1997) Address and...
| CAS | 213130-17-7 |
| MW: | 1367.6 D |
225.00€
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M871
Item number: TGM-TP1994-1mg
Description: Selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM for GAL2 and GAL1 receptors respectively). Blocks the pro-nociceptive effect of GAL2 receptor agonists. References: Jimenez-Andrade et al (2006) Activation of peripheral galanin receptors: differential effects on nociception....
| CAS | 908844-75-7 |
| MW: | 2287.64 D |
1,450.00€
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MAIT 203
Item number: TGM-TP1995-1mg
Description: Inhibits interaction of APC and Asef (RhoGEF4). Inhibits colorectal cancer cell migration and invasion in vitro. References: Jiang et al (2017) Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat.Chem.Biol. 13 994 PMID:
| MW: | 2517.83 D |
202.00€
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MEN 11270
Item number: TGM-TP1999-5mg
Description: Peptide antagonist of the B2 bradykinin receptor (pKi = 10.3), conformationally constrained cyclized analog of HOE 140. Blocks hypotension and bronchoconstriction in vivo. Displays selectivity for B2 over 29 other receptors and ion channels (pIC50 < 5.5). References: Meini et al (1999) MEN 11270, a...
| CAS | 235082-52-7 |
| MW: | 1299.56 D |
253.00€
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Kisspeptin-54(human)
Item number: TGM-TP2005-100ug
Description: Potent endogenous ligand of the kisspeptin receptor (KISS1, GPR54). Binds with high affinity to rat and human KISS1 receptors with Ki values of 1.80 and 1.45 nM respectively. Inhibits chemotaxis, invasion and metastasis of human melanomas and breast carcinomas. Stimulates gonadotropin secretion...
| Keywords: | Metastin (human) |
| MW: | 5857.49 D |
1,355.00€
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K 41498 aceate
Item number: TGM-TP2009L-100mg
Description: K41498 acetate, an analogues of antisauvagine-30 (aSvg-30), inhibits sauvagine-stimulated cAMP accumulation in hCRF2alpha- and hCRF2beta-expressing cells. K41498 acetate is a potent and highly selective antagonist CRF2 receptor with Ki values of 0.66 nM, 0.62 nM and 425 nM for human CRF2alpha, CRF2beta...
From 319.00€
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