Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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NMDAR/HDAC-IN-1
Item number: TGM-T61451-100mg
Description: NMDAR/HDAC-IN-1 (Compound 9d) is a potent dual inhibitor of N-methyl-D-aspartate receptors (NMDARs) and histone deacetylases (HDACs), with a high affinity for NMDARs (Ki = 0.59 µM) and significant inhibitory effects on various HDAC isoforms, including HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8 with IC50...
| MW: | 368.47 D |
From 1,440.00€
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OXS007417
Item number: TGM-T61456-100mg
Description: OXS007417, a chemical compound, exhibits in vitro induction of differentiation in acute myeloid leukemia cells with a half-maximal effective concentration of 48 nM (EC 50 = 48 nM). Additionally, it demonstrates significant antitumor effects in vivo. Target: Others
| MW: | 369.34 D |
From 1,440.00€
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Tubulin inhibitor 19
Item number: TGM-T61459-100mg
Description: Tubulin inhibitor 19 (compound 9b) is a potent indole chalcone compound exhibiting strong tubulin inhibitory activity, making it valuable for cancer research [1]. Target: Others
| MW: | 369.41 D |
From 1,440.00€
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Monoamine oxidase/Aromatase-IN-1
Item number: TGM-T61463-100mg
Description: Monoamine oxidase/Aromatase-IN-1 (compound 2q) is a potent dual inhibitor of monoamine oxidase (MAO) and aromatase, with IC50 values of 39 nM for MAO-B and 31 nM for aromatase. It holds significant potential for research in neurological disorders and breast cancer [1]. Target: Others
| MW: | 369.44 D |
From 1,440.00€
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PptT-IN-3
Item number: TGM-T61466-100mg
Description: PptT-IN-3 (compound 5p) is a powerful inhibitor (IC50 = 3.5 µM) of phosphopantetheinyl phosphoryl transferase (PptT), an indispensable enzyme involved in the synthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. This compound holds promise for tuberculosis research [1]....
| MW: | 369.48 D |
From 1,440.00€
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RAD51-IN-8
Item number: TGM-T61469-100mg
Description: RAD51-IN-8, a new RAD51 binder, is a RAD51-BRCA2 inhibitor that disrupts the RAD51 BRCA2 protein-protein interaction in the micromolar range. This protein-protein interaction (PPI) inhibitor also demonstrates inhibitory activity for H4A4 with an EC50 value of 19 µM [1]. Target: Others
| MW: | 370.21 D |
From 1,440.00€
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Antitubercular agent-13
Item number: TGM-T61471-100mg
Description: Antitubercular agent-13 (Compound 3d) is an antitubercular compound with MIC values of 0.007 µg/mL against MTB H37Rv and 1.851 µg/mL against MDR-MTB 16833, respectively, and exhibits metabolic instability [1]. Target: Others
| MW: | 370.36 D |
From 1,440.00€
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HDAC6-IN-13
Item number: TGM-T61474-100mg
Description: HDAC6-IN-13 (Compound 35m) is a potent and highly selective orally active inhibitor of HDAC6, with an IC50 of 0.019 µM. It also inhibits HDAC1, HDAC2, and HDAC3, with IC50 values of 1.53 µM, 2.06 µM, and 1.03 µM, respectively. HDAC6-IN-13 exhibits substantial blood-brain barrier permeability and...
| MW: | 370.45 D |
From 1,440.00€
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ROS1-IN-1
Item number: TGM-T61478-100mg
Description: ROS1-IN-1 (Compound 31) is a highly effective and specific ROS1 kinase inhibitor, with an inhibitory concentration (IC50) of 0.097 µM [1]. Target: Others
| MW: | 370.86 D |
From 1,440.00€
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LasR-IN-1
Item number: TGM-T61484-100mg
Description: LasR-IN-1 (compound 9g) is a highly potent LasR inhibitor, effective against E. coli and exhibiting significant antibacterial properties with a minimum inhibitory concentration (MIC) of 28.13 µM against P. aeruginosa [1]. Target: Others
| MW: | 371.43 D |
From 1,440.00€
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VEGFR-2/DHFR-IN-1
Item number: TGM-T61489-100mg
Description: VEGFR-2/DHFR-IN-1 (compound 8b) is a chemical inhibitor of VEGFR-2 and DHFR, with IC50 values of 0.384 µM and 7.881 µM, respectively. It possesses effective antibacterial activity against pathogens including Escherichia coli, Streptococcus faecalis, Salmonella enterica, MSSA, and MRSA, with MIC values...
| MW: | 371.81 D |
From 1,440.00€
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P2X receptor-1
Item number: TGM-T61490-100mg
Description: P2X receptor-1 is a potential inhibitor of P2X receptor, used in the treatment of pain and inflammation. Target: Others
| MW: | 371.86 D |
From 1,440.00€
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