Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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FAK-IN-3
Item number: TGM-T63545-100mg
Description: FAK-IN-3 is a potent inhibitor of adherens spot kinase (FAK). FAK-IN-3 reduces migration and invasion of PA-1 cells and inhibits the expression of MMP-2 and MMP-9. FAK-IN-3 inhibits tumor growth and metastasis with no significant adverse effects. FAK-IN-3 has shown investigational potential in ovarian...
| MW: | 512.56 D |
From 1,440.00€
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MEK1/2-IN-2
Item number: TGM-T63547-100mg
Description: MEK1/2-IN-2 is a potent, ATP-competitive MEK1/2 inhibitor that exhibits equal inhibitory effects on both wild-type MEK1/2 and a range of MEK1/2 mutant cells. Target: Others
| MW: | 512.97 D |
From 1,440.00€
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MRGPRX1 agonist 4
Item number: TGM-T63549-100mg
Description: MRGPRX1 agonist 4 is a potent and orally active Mas-related G protein-coupled receptor X1 (MRGPRX1) positive conformation modulator (EC50: 0.1 µM). MRGPRX1 agonist 4 ameliorated the behavioral thermal allergic response in mice, a model of MRGPRX1 neuropathic pain. Target: Others
| MW: | 513.36 D |
From 1,440.00€
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Complex III-IN-1
Item number: TGM-T61009-100mg
Description: Complex III-IN-1 (Compd 4c-2) is an inhibitor of complex III with antifungal activity, exhibiting an EC50 value of 18.53 mg/L against Sclerotinia sclerotiorum [1]. Target: Others
| MW: | 333.9 D |
From 1,440.00€
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Galectin-8-IN-1
Item number: TGM-T61014-100mg
Description: Galectin-8-IN-1 is a selective ligand for the galectin-8 N-terminal domain (galectin-8N) with a Kd value of 48 µM, demonstrating 15-fold greater selectivity compared to galectin-3 and outperforming other mammalian galectins. Target: Others
| MW: | 334.32 D |
From 1,440.00€
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Topoisomerase II inhibitor 6
Item number: TGM-T61017-100mg
Description: Topoisomerase II inhibitor 6 (Compound 5), a tryptanthrin derivative, is a potent and selective topoisomerase II inhibitor that blocks the CCRF-CEM cell cycle in the G2 phase and induces DNA double-strand breaks (DSB). It exhibits antiproliferative activity on various tumor cell lines and has potential...
| MW: | 334.37 D |
From 1,440.00€
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FAK-IN-4
Item number: TGM-T61019-100mg
Description: FAK-IN-4 (Compound 7d) exhibits anticancer activities by inducing cell apoptosis and is a potential inhibitor of FAK [1]. Target: Others
| MW: | 334.41 D |
From 1,440.00€
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LSD1-IN-16
Item number: TGM-T61021-100mg
Description: LSD1-IN-16 (compound 4b) is a potent inhibitor of LSD1 that inhibits LSD1-CoREST, MAO-A, and MAO-B with IC50 values of 0.015, 0.024, and 0.366 µM, respectively. LSD1-IN-16 also induces cell growth arrest in prostate cancer LNCaP cells with an IC50 value of 15.2 µM [1]. Target: Others
| MW: | 334.43 D |
From 1,440.00€
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LSD1-IN-17
Item number: TGM-T61022-100mg
Description: LSD1-IN-17 (compound 5b) is a potent inhibitor of LSD1, effectively inhibiting LSD1-CoREST, MAO-A, and MAO-B with IC50 values of 0.005, 0.028, and 0.820 µM, respectively. It induces cell growth arrest in prostate cancer LNCaP cells with an IC50 value of 17.2 µM [1]. Target: Others
| MW: | 334.43 D |
From 1,440.00€
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HIV-1 inhibitor-41
Item number: TGM-T61031-100mg
Description: HIV-1 inhibitor-41 (Compound B23) is an orally active non-nucleoside HIV-1 reverse transcriptase inhibitor with EC50 values of 50 nM against the mutant E138K strain and 20.8 nM against HIV-1 WT. HIV-1 inhibitor-41 exhibits low hERG inhibition, no apparent CYP enzymatic inhibition, and no acute toxicity...
| MW: | 335.37 D |
From 1,440.00€
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Carbonic anhydrase inhibitor 10
Item number: TGM-T61032-100mg
Description: Carbonic anhydrase inhibitor 10 can be used in the research of cancer that shows anti-proliferative activity against MCF-7 cancer cell line with an IC50 of 11.9 µM. Carbonic anhydrase inhibitor 10 is a potent inhibitor of h CA IX with a Ki value of 6.2 nM [1]. Target: Others
| MW: | 335.38 D |
From 1,440.00€
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CXCR2 antagonist 5
Item number: TGM-T61235-100mg
Description: CXCR2 antagonist 5 (compound 25) is a potent CXCR2 antagonist with strong binding affinity (IC50 = 0.013 µM) and effective calcium mobilization (IC50 = 0.1 µM) [1]. Target: Others
| MW: | 352.36 D |
From 1,440.00€
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