Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
No results were found for the filter!
TCMDC-135051 hydrochloride
Item number: TGM-T63488-100mg
Description: TCMDC-135051 hydrochloride is a potent, highly selective, low off-target toxicity inhibitor of the protein kinase PfCLK3. TCMDC-135051 hydrochloride blocks the trophozoite to lysosome transition, disrupts transcription and inhibits transmission to mosquito vectors, exhibiting an antiparasitic effect...
| MW: | 508.05 D |
From 1,137.00€
*
MtTMPK-IN-8
Item number: TGM-T63491-100mg
Description: MtTMPK-IN-8 is a moderately potent inhibitor of Mycobacterium thymidylate kinase (MtbTMPK) with no significant cytotoxicity, exhibiting submicromolar activity (MICs = 0.78-9.4 µM) against Mycobacterium and capable of being used in the study of tuberculosis. Target: Others
| MW: | 508.48 D |
From 1,440.00€
*
CYP2C1/CYP2C19-IN-2
Item number: TGM-T63495-100mg
Description: CYP2C1/CYP2C19-IN-2 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection. Target: Others
| MW: | 508.59 D |
From 1,440.00€
*
CYP2C9/CYP2C19-IN-1
Item number: TGM-T63496-100mg
Description: CYP2C9/CYP2C19-IN-1 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection. Target: Others
| MW: | 508.59 D |
From 1,440.00€
*
Chroman 1 dihydrochloride
Item number: TGM-T63506-100mg
Description: Chroman 1 dihydrochloride is a selective and potent inhibitor of ROCK, acting more strongly on ROCK2 (IC50: 1 pM) than ROCK1 (IC50: 52 pM) and also inhibiting MRCK activity (IC50: 150 nM). Target: Others
| MW: | 509.43 D |
From 1,440.00€
*
Top/HDAC-IN-1
Item number: TGM-T63509-100mg
Description: Top/HDAC-IN-1 is a dual topoisomerase (Top)/HDAC inhibitor that acts on HDAC1 (IC50: 18 nM), HDAC2 (IC50: 230 nM), HDAC3 (IC50: 790 nM), HDAC6 (IC50: 87 nM) and HDAC8 (IC50: 5250 nM). Top/HDAC-IN-1 exhibited potent antitumor effects on HCT116 cells (IC50: 180 nM), blocked the cell cycle of HCT116 cells...
| MW: | 509.56 D |
From 1,440.00€
*
PPARgamma agonist 1
Item number: TGM-T63514-100mg
Description: PPARgamma agonist 1 is a potent agonist of PPARgamma that efficiently activates hPPARgamma without causing full agonism, thereby avoiding adverse effects. ppargamma agonist 1 has shown research potential in cardiovascular diseases associated with metabolic disorders. Target: Others
| MW: | 509.68 D |
From 1,440.00€
*
Bcl-2-IN-7
Item number: TGM-T63521-100mg
Description: Bcl-2-IN-7 is a potent inhibitor of Bcl-2 (b-cell lymphoma-2), which can downregulate the expression of Bcl-2, increase the expression of p53, Bax, caspase-7 mRNA, and induce cell cycle arrest and apoptosis in MCF-7 cells of breast cancer. Bcl2-IN-7 showed good antitumor activity against MCF-7 cells...
| MW: | 510.59 D |
From 1,440.00€
*
Antitubercular agent-23
Item number: TGM-T63525-100mg
Description: Antitubercular agent-23 is an effective anti-Candida and anti-tuberculosis agent against Candida albicans MTCC 3017 (MIC: 1.1 µg/ml) and M. tuberculosis (H37Rv) (MIC: 1 µg/ml). Target: Others
| MW: | 511.48 D |
From 1,440.00€
*
Topoisomerase I/II inhibitor 4
Item number: TGM-T63526-100mg
Description: Topoisomerase I/II inhibitor 4 is a potent dual inhibitor of topoisomerase I (Topo I) and II (Topo II) with inhibitory effects on cell proliferation, invasion and migration, and induction of apoptosis, and can be used to study hepatocellular carcinoma. Target: Others
| MW: | 511.49 D |
From 1,440.00€
*
HSP90-IN-11
Item number: TGM-T63528-100mg
Description: HSP90-IN-11 is a potent inhibitor of HSP90 and induces significant accumulation of the sub-G1 population. HSP90-IN-11 has a potent HSP90alpha inhibitory effect comparable to that of AUY-922 (Luminespib). In CRC and NSCLC cells, HSP90-IN-11 exhibited significant anti-proliferative activity in the...
| MW: | 511.54 D |
From 1,440.00€
*
ZIKV-IN-4
Item number: TGM-T63533-100mg
Description: ZIKV-IN-4 is a low cytotoxic, acid-stable anti-ZIKV agent with an EC50 value of 3.49 µM. ZIKV-IN-4 exhibited potent inhibition of ZIKV NS5 MTase. Target: Others
| MW: | 511.65 D |
From 1,440.00€
*