Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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AChE-IN-8
Item number: TGM-T61648-100mg
Description: AChE-IN-8 (Compound 19) is a highly potent acetylcholinesterase (AChE) inhibitor with an IC50 value of 1.95 µM, showing promise for Alzheimer's disease research [1]. Target: Others
| MW: | 382.48 D |
From 1,440.00€
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SBI-581
Item number: TGM-T61663-100mg
Description: SBI-581 is an orally active, potent selective inhibitor of serine-threonine kinase TAO3, with an IC 50 of 42 nM. It effectively promotes the accumulation of TKS5alpha at RAB11-positive vesicles and inhibits the formation of invadopodia. Additionally, SBI-581 exhibits reasonable pharmacokinetics in mice...
| MW: | 383.44 D |
From 1,374.00€
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Antibacterial agent 118
Item number: TGM-T61665-100mg
Description: Antibacterial agent 118 (also known as compound 20) is a potent antimycobacterial compound with activity against various mycobacterial strains, including Mtb H37Ra, M. aurum, M. smegmatis, Mtb H37Rv, and M. avium. The minimum inhibitory concentration (MIC) values for Antibacterial agent 118 against...
| MW: | 383.47 D |
From 1,440.00€
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CHIKV-IN-3
Item number: TGM-T61675-100mg
Description: CHIKV-IN-3 is a potent inhibitor effective against two low-passage CHIKV strains, with EC50 values of 1.55 µM for CHIKV-122508 and 0.14 µM for CHIKV-6708, respectively. It targets host cells to disrupt viral replication while maintaining minimal cytotoxic liability (CC50 > 100 µM). Additionally,...
| MW: | 383.95 D |
From 1,440.00€
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Nrf2 activator-2
Item number: TGM-T61688-100mg
Description: Nrf2 activator-2 (referred to as compound O15), an Osthole derivative, is a highly potent Nrf2 agonist exhibiting an EC 50 of 2.9 µM in 293 T cells. By effectively disrupting the binding between Keap1 and Nrf2, Nrf2 activator-2 activates the Nrf2 pathway. Furthermore, this compound significantly reduces...
| MW: | 385.25 D |
From 932.00€
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Tubulin polymerization-IN-6
Item number: TGM-T61532-100mg
Description: Tubulin polymerization-IN-6 (compound 5f) is a potent tubulin polymerization inhibitor with an IC50 of 1.09 µM. It inhibits cell migration and tube formation, exhibits anti-angiogenic properties, and effectively hinders tumor growth in HT29 xenograft Balb/c nude mice [1]. Target: Others
| MW: | 375.37 D |
From 1,440.00€
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DNA-PK-IN-9
Item number: TGM-T61533-100mg
Description: DNA-PK-IN-9 (also known as compound YK6) is a highly potent inhibitor of DNA-dependent protein kinase (DNA-PK), displaying an IC50 value of 10.47 nM. DNA-PK-IN-9 holds significant potential in anticancer research [1]. Target: Others
| MW: | 375.42 D |
From 1,440.00€
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AXKO-0046
Item number: TGM-T61539-25mg
Description: AXKO-0046 is an indole derivative and small-molecule LDHB selective inhibitor. Target: Others
| MW: | 375.55 D |
From 1,665.00€
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VEGFR-2-IN-17
Item number: TGM-T61542-100mg
Description: VEGFR-2-IN-17 (Compound 15a) is a highly potent inhibitor of Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2) with an IC50 of 67.25 nM and exhibits significant antitumor properties [1]. Target: Others
| MW: | 375.81 D |
From 1,440.00€
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CLK1/4-IN-1
Item number: TGM-T61543-100mg
Description: CLK1/4-IN-1 (compound 31) is a highly potent and selective inhibitor of Clk1 and Clk4, with IC50 values of 9.7 nM and 6.6 nM, respectively. It effectively inhibits the growth of T24 cancer cells, with a GI50 value of 1.1 µM. CLK1/4-IN-1 has shown promising potential as an anticancer research tool [1]....
| MW: | 375.83 D |
From 1,440.00€
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HDAC8-IN-2
Item number: TGM-T61549-100mg
Description: HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor with IC50 values of 0.27 µM and 0.32 µM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. It effectively kills schistosome larvae and significantly reduces egg laying in adult worm pairs [1]. Target: Others
| MW: | 376.36 D |
From 1,440.00€
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Antileishmanial agent-5
Item number: TGM-T61560-100mg
Description: Antileishmanial agent-4 is a ribonucleoside analogue with potent activity against L. infantum and T. cruzi, exhibiting EC50 values of 0.68 µM and 0.83 µM, respectively [1]. Target: Others
| MW: | 376.79 D |
From 1,440.00€
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