Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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EGFR-IN-44
Item number: TGM-T63784-100mg
Description: EGFR-IN-44 is a potent, orally active inhibitor of EGFRtyrosine kinase (IC50: 4.11 nM). EGFR-IN-44 has an oral bioavailability of 33.57% and induces apoptosis. EGFR-IN-44 can be used to study non-small cell lung cancer. Target: Others
| MW: | 537.08 D |
From 1,440.00€
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beta-Glucuronidase/hCAII-IN-2
Item number: TGM-T63789-100mg
Description: beta-Glucuronidase/hCAII-IN-2 is a potent inhibitor of beta-glucuronidase and hCA II, and their IC50 values were 670.7 µM and 21.77 µM, respectively. Target: Others
| MW: | 537.52 D |
From 1,440.00€
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GID4 Ligand 1
Item number: TGM-T63799-100mg
Description: GID4 Ligand 1 is a cell-permeable, highly selective GID4 binder with an IC50 value of 5.4 µM and a Kd value of 5.6 µM. GID4 Ligand 1 is capable of binding GID4 in cells with an EC50 value of 558 nM. GID4 Ligand 1 is capable of being used in the synthesis of PROTACs. Target: Others
| MW: | 538.66 D |
From 1,440.00€
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ZM223 hydrochloride
Item number: TGM-T63800-100mg
Description: ZM223 hydrochloride is a potent, non-covalent, orally active inhibitor of NEDD8 activase (NAE). Target: Others
| MW: | 538.99 D |
From 1,175.00€
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BTK-IN-7
Item number: TGM-T63810-100mg
Description: BTK-IN-7 is a selective and potent BTK inhibitor with an IC50 value of 4.0 nM. BTK-IN-7 exhibits high selectivity at both the enzymatic (ITK>250-fold, EGFR>2500-fold) and cellular levels (ITK>227-fold, EGFR27-fold). BTK-IN-7 exhibits high high antitumor effect. Target: Others
| MW: | 540.61 D |
From 1,440.00€
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FGFR1 inhibitor-6
Item number: TGM-T63816-100mg
Description: FGFR1 inhibitor-6 is a potent FGFR1 inhibitor (IC50: 16.31 nM) with cytotoxic activity, capable of blocking the cell cycle in pro-G1 and G2/M phases, and inducing apoptosis. Target: Others
| MW: | 541.6 D |
From 1,440.00€
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K20
Item number: TGM-T63823-100mg
Description: K20 is a potent and selective inhibitor of KRas G12C (IC50: 1.16 nM). In H358 cells, K20 demonstrates an anticancer effect with an IC50 value of 0.78 µM and inhibits the growth of NCI-H358 tumor cells (TGI: 41%) without significant toxicity. K20 reduces the phosphorylation level of Erk, leading to...
| MW: | 543.34 D |
From 1,440.00€
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Antiallergic agent-1
Item number: TGM-T63825-100mg
Description: Antiallergic agent-1, an Src family kinase inhibitor, is a new and valuable lead compound with potential as an anti-allergic agent. Target: Others
| MW: | 543.46 D |
From 1,440.00€
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HSP90-IN-10
Item number: TGM-T63827-100mg
Description: HSP90-IN-10 is a potent inhibitor of HSP90. HSP90-IN-10 exhibits potent anti-proliferative effects on HCC1954 breast cancer cells (IC50: 6 µM). hSP90-IN-10 induces apoptosis without inhibiting the growth of normal epithelial cells. Target: Others
| MW: | 543.54 D |
From 1,440.00€
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Hsp90-IN-16
Item number: TGM-T63828-100mg
Description: Hsp90-IN-16 is an HSP90 inhibitor that acts effectively and highly selectively on HER2-positive cancer cells.Hsp90-IN-16 inhibits the proliferation of HCC1954 breast cancer cells with an IC50 value of 6 µM.Hsp90-IN-16 inhibits HSP90 "client "proteins, including a key oncogenic receptor HER2/neu, induced...
| MW: | 543.54 D |
From 1,440.00€
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SID 26681509 quarterhydrate
Item number: TGM-T63831-100mg
Description: SID 26681509 quarterhydrate is a reversible, potent, selective, competitive inhibitor of human cathepsin L (IC50: 56 nM). SID 26681509 inhibits in vitro propagation of Plasmodium falciparum (IC50: 15.4 µM) and inhibits Leishmania major (IC50: 12.5 µM) and does not inhibit histone G activity. Target: Others
| MW: | 544.16 D |
From 1,431.00€
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AAK1-IN-2 TFA
Item number: TGM-T63833-100mg
Description: AAK1-IN-2 TFA (compound (S)-31) is a selective and potent inhibitor of AAK1 with an IC50 of 5.8 nM, capable of crossing the blood-brain barrier. Target: Others
| MW: | 544.45 D |
From 1,440.00€
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