Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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12272 from 12274 pages
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TRPC4/5-IN-1
TRPC4/5-IN-1

Item number: TGM-T60981-100mg

Description: TRPC4/5-IN-1 can be used for the research of skin inflammatory diseases and proteinuric kidney diseases. TRPC4/5-IN-1 is a potent inhibitor of TRP channel 5/4 (TRPC5/4) with IC50 values of 0.54 µM and 2.06 µM, respectively. [1]. Target: Others
MW: 331.41 D
From 1,440.00€ *
Review
KCa2 channel modulator 2
KCa2 channel modulator 2

Item number: TGM-T60986-100mg

Description: KCa2 channel modulator 2 (compound 2q) is an effective, subtype-selective K/Ca 2 channel positive modulator with similar potency on the human K Ca 2.3 channel and rat K Ca 2.2a subtypes, exhibiting EC50 values of 0.60 µM and 0.64 µM, respectively [1]. Target: Others
MW: 331.78 D
From 1,440.00€ *
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FTO-IN-6
FTO-IN-6

Item number: TGM-T60994-100mg

Description: FTO-IN-6 is a selective inhibitor of the fat mass and obesity-associated protein (FTO). Target: Others
MW: 332.27 D
From 1,440.00€ *
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GL0388
GL0388

Item number: TGM-T60997-100mg

Description: GL0388 is a Bax activator and leads to Bax insertion into mitochondrial membrane that induce Bax-mediated apoptosis. GL0388 inhibits tumor growth of breast cancer xenograft in vivo which also exhibits antiproliferative activities against a variety of cancer cells with IC50 values of 0.299-1.57 µM [1]....
MW: 332.37 D
From 834.00€ *
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AEP-IN-1
AEP-IN-1

Item number: TGM-T61004-100mg

Description: APE-IN-1 can be used for the early diagnosis and drug research of Alzheimer's disease. APE-IN-1 is a potent Asparagine endopeptidase (AEP) inhibitor with IC 50 value of 89 nM [1]. Target: Others
MW: 333.43 D
From 1,440.00€ *
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CA IX-IN-1
CA IX-IN-1

Item number: TGM-T62387-100mg

Description: CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) with demonstrated antitumour effects. Target: Others
MW: 430.43 D
From 1,440.00€ *
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KB-5492 FA
KB-5492 FA

Item number: TGM-T62396L-10mg

Description: KB-5492 FA is a selective sigma receptor inhibitor with antiulcerogenic effects.CAS ??128-52-56-8. Target: Sigma receptor. Smiles: O=C(CN1CCN(CC1)CC2=CC(OC)=C(C(OC)=C2)OC)OC3=CC=C(C=C3)OC.[H]C(O)=O. References: Morimoto Y,et al. Effects of KB-5492, a new anti-ulcer agent, on ethanol- and acidified...
Keywords: KB-5492 FA(113594-64-2 Free base)
MW: 476.52 D
From 53.00€ *
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KDM1/CDK1-IN-1
KDM1/CDK1-IN-1

Item number: TGM-T62405-100mg

Description: KDM1/CDK1-IN-1 (compound 4) is a potent inhibitor of KDM1 (IC50: 0.096 µM) and CDK1 (IC50: 0.078 µM), blocking the cell cycle of HOP-92 cells in the G2/M phase and inducing apoptosis. It is highly cytotoxic to CCRF-CEM cells (IC50: 16.34 µM), HOP-92 cells (IC50: 3.45 µM), and Hep-G2 cells (IC50: 7.79...
MW: 431.47 D
From 1,440.00€ *
Review
AD012
AD012

Item number: TGM-T62831-100mg

Description: AD012 is a dual inhibitor of cACE/NEP that utilizes the previously reported C-domain selective ACE inhibitor lenopril-tryptophan synthesis, potentially offering potent anti-hypertensive and cardioprotective effects. Target: Others
MW: 456.53 D
From 1,440.00€ *
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Antitumor agent-54
Antitumor agent-54

Item number: TGM-T62835-100mg

Description: Antitumor agent-54 (Compound C11) is a 14-3-3eta protein inhibitor (KD: 35 µM). antitumor agent-54 inhibits several typical human hepatocellular carcinoma cell lines. antitumor agent-54 blocks the cell cycle in the G1-S phase and induces apoptosis, showing good metabolic stability. It exhibits good...
MW: 456.58 D
From 1,440.00€ *
Review
Hit 1
Hit 1

Item number: TGM-T62836-100mg

Description: Hit 1, an activator of insulin-degrading enzymes (IDE) (EC50: 5.5 µM), reduces glucose-stimulated insulin secretion. Target: Others
MW: 456.58 D
From 1,440.00€ *
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AR antagonist 4
AR antagonist 4

Item number: TGM-T62838-100mg

Description: AR antagonist 4 (Compound 67-b) is an orally active androgen receptor (AR) antagonist with an IC50 of 246.6 nM for wild-type AR. Target: Others
MW: 456.62 D
From 1,440.00€ *
Review
12272 from 12274 pages