Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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HER2-IN-11
Item number: TGM-T60896-100mg
Description: HER2-IN-11 is a psoralen derivative that induces apoptosis, exhibits light-activated cytotoxicity, and demonstrates anti-breast cancer activity [1]. Target: Others
| MW: | 325.27 D |
From 1,440.00€
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HbF inducer-1
Item number: TGM-T60898-100mg
Description: HbF inducer-1 is a fetal hemoglobin inducer which is orally bioavailable. Target: Others
| MW: | 325.36 D |
From 1,440.00€
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IRAK4-IN-11
Item number: TGM-T60899-100mg
Description: IRAK4-IN-11 (compound 6) is a potent IRAK4 inhibitor with an IC50 of 0.008 µM, demonstrating cell pIRAK4 potencies with an IC50 of 0.19 µM [1]. Target: Others
| MW: | 325.37 D |
From 1,440.00€
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Miaosporone A
Item number: TGM-T60906-100mg
Description: Miaosporone A is an angucyclic quinone which shows cytotoxic activities against both cancerous (MCF-7 and NCI-H187) and nonmalignant (Vero) cells. Miaosporone A has antibacterial activity against Mycobacterium tuberculosis and antimalarial activity against Plasmodium falciparum K1 with IC50 values of...
| MW: | 326.34 D |
From 1,440.00€
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EGFR/HER2-IN-8
Item number: TGM-T60938-100mg
Description: EGFR/HER2-IN-8 (compound 34) is an inhibitor of EGFR, HER2, and DHFR with IC50 values of 0.45 µM, 0.244 µM, and 5.669 µM, respectively. It demonstrates anticancer activity against several cancer cell lines, exhibiting a high safety profile and selectivity indices, making it useful for cancer research...
| MW: | 328.39 D |
From 1,440.00€
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ChE/Abeta1-42-IN-1
Item number: TGM-T60940-100mg
Description: ChE/Abeta1-42-IN-1 (compound 28) is a potent aggregation inhibitor of ChE and Abeta1-42 with excellent BBB permeability, exhibiting IC50 values of 0.062 µM for AChE, 0.767 µM for BuChE, and 1.227 µM for Abeta1-42 aggregation. ChE/Abeta1-42-IN-1 is a potent multi-targeted anti-Alzheimer's disease agent...
| MW: | 328.41 D |
From 1,440.00€
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LSD1-IN-15
Item number: TGM-T60941-100mg
Description: LSD1-IN-15 (compound 1b) is a potent LSD1 inhibitor that inhibits LSD1-CoREST, MAO-A, and MAO-B with IC50 values of 0.149, 0.028, and 0.327 µM, respectively. LSD1-IN-15 induces cell growth arrest in LNCaP cells of prostate cancer, with an IC50 value of 9.9 µM [1]. Target: Others
| MW: | 328.41 D |
From 1,440.00€
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MC2652
Item number: TGM-T60942-100mg
Description: MC2652 (compound 1a) is a potent LSD1 inhibitor with high inhibitory effects in MV4-11 and NB4 leukemia cells and exhibits antiproliferative activity against LNCaP prostate cancer cells [1]. Target: Others
| MW: | 328.41 D |
From 1,440.00€
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Antitubercular agent-15
Item number: TGM-T60945-100mg
Description: Antitubercular agent-15 (Compound 5n) is an antitubercular agent with low cytotoxicity against pulmonary fibroblasts and macrophages. The MIC90 values against M. tuberculosis H37Rv, CF16, CF61, CF76, CF152, and CF161 are 0.73, 7.69, 9.38, 18.80, 7.53, and 7.31 µg/mL, respectively [1]. Target: Others
| MW: | 328.47 D |
From 1,440.00€
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Complex III-IN-2
Item number: TGM-T60949-100mg
Description: Complex III-IN-2 (Compd 4d-2) is a complex III inhibitor with antifungal activity, exhibiting EC50 values of 29.31 mg/L against R. solani and 29.98 mg/L against Sclerotinia sclerotiorum [1]. Target: Others
| MW: | 328.86 D |
From 1,440.00€
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Antitumor agent-50
Item number: TGM-T60975-100mg
Description: Antitumor agent-50 (compound 1a) is a thiazolidinone. Antitumor agent-50 is an effective antitumor agent that has the potential for the research of osteosarcoma (OS) [1]. Target: Others
| MW: | 331.36 D |
From 1,440.00€
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COX-2-IN-7
Item number: TGM-T60978-100mg
Description: COX-2-IN-7 (compound 4a) is a potent and selective COX-2 inhibitor with greater selectivity than Celecoxib and an IC50 value of 6.585 µM. It exhibits good anti-inflammatory properties and low ulcerogenic activity in vivo[1]. Target: Others
| MW: | 331.41 D |
From 1,440.00€
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