Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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12270 from 12274 pages
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AChE/BChE-IN-3 hydrochloride
AChE/BChE-IN-3 hydrochloride

Item number: TGM-T60831-100mg

Description: AChE/BChE-IN-3 (BMC-1) hydrochloride is a dual inhibitor of AChE and BChE, with IC50 values of 0.383 µM against equine serum BChE (eqBChE) and 6.08 µM against electric eel AChE (elAChE) [1]. Target: Others
MW: 316.82 D
From 1,440.00€ *
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SARS-CoV-2-IN-23
SARS-CoV-2-IN-23

Item number: TGM-T60841-100mg

Description: SARS-CoV-2-IN-23 (compound GRL-0617) is an inhibitor of SARS-CoV-2 papain-like protease (PLpro) with an IC50 of 2.3 µM [1]. Target: Others
MW: 318.41 D
From 1,440.00€ *
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GABAA receptor agonist 1
GABAA receptor agonist 1

Item number: TGM-T60842-100mg

Description: GABAA receptor agonist 1 (compound 3e) is a potent agonist that binds to the GABA binding site of the GABAA receptor, producing GABAergic effects and exhibiting anti-depression activities in classical mouse models of FST and TST, indicating its potential in depression research [1]. Target: Others
MW: 318.45 D
From 1,440.00€ *
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Heme Oxygenase-2-IN-1
Heme Oxygenase-2-IN-1

Item number: TGM-T60847-100mg

Description: Heme Oxygenase-2-IN-1 (Compound 9) is a potent, selective inhibitor of heme oxygenase-2 (HO-2), with IC50 values of 14.9 µM for HO-1 and 0.9 µM for HO-2 [1]. Target: Others
MW: 319.36 D
From 1,440.00€ *
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Carbonic anhydrase inhibitor 3
Carbonic anhydrase inhibitor 3

Item number: TGM-T60848-100mg

Description: Carbonic anhydrase inhibitor 3 (compound 11g) is a carbonic anhydrase II inhibitor that reduces intraocular pressure in glaucomatous rabbits [1]. Target: Others
MW: 319.38 D
From 1,440.00€ *
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SARS-CoV-2 nsp3-IN-1
SARS-CoV-2 nsp3-IN-1

Item number: TGM-T60861-100mg

Description: SARS-CoV-2 nsp3-IN-1 (Compound 15c) exhibits significant selectivity for coronavirus macrodomains, particularly SARS-CoV-2 Mac1, and can inhibit Mac1 ADP-ribosylhydrolase activity with an IC50 of 6.1 µM [1]. Target: Others
MW: 321.33 D
From 1,440.00€ *
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Antibacterial agent 78
Antibacterial agent 78

Item number: TGM-T60865-100mg

Description: Antibacterial agent 78 (compound 30) is an antibacterial agent with an improved cytotoxicity profile[1]. Target: Others
MW: 321.5 D
From 1,440.00€ *
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Avibactam sodium dihydrate
Avibactam sodium dihydrate

Item number: TGM-T60874-100mg

Description: Avibactam sodium (NXL-104) dihydrate inhibits CTX-M-15 and beta-lactamase TEM-1 with IC50 values of 5 nM and 8 nM, respectively, and is a reversible covalent inhibitor of non-beta-lactam beta-lactamase [1]. Target: Others
MW: 323.26 D
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5-Ph-IAA-AM
5-Ph-IAA-AM

Item number: TGM-T60878-10mg

Description: 5-Ph-IAA-AM, an eggshell-permeable analog of 5-Ph-IAA, enhances protein degradation in laid embryos and can be used to reveal the roles of temporally controlled protein degradation in C. elegans embryogenesis and development [1]. Target: Others
MW: 323.34 D
From 840.00€ *
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MLKL-IN-1
MLKL-IN-1

Item number: TGM-T60885-100mg

Description: MLKL-IN-1, a covalent inhibitor of MLKL, has a dissociation constant (Kd) of 50 µM. Target: Others
MW: 324.37 D
From 1,440.00€ *
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NiCur
NiCur

Item number: TGM-T60888-100mg

Description: NiCur blocks CBP HAT activity and downregulates p53 activation upon genotoxic stress. NiCur is a potent and selective inhibitor of CBP histone acetyltransferase (HAT) with an IC 50 value of 0.35 µ?. NiCur can be used to perform mechanistic studies without affecting target proteins expression [1]....
MW: 324.38 D
From 585.00€ *
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JAK-2/3-IN-3
JAK-2/3-IN-3

Item number: TGM-T60895-100mg

Description: JAK-2-/3-IN-3 (compound ST4j) is a potent inhibitor of JAK2/3, with IC50 values of 13.00 and 14.86 nM for JAK2 and JAK3, respectively. It inhibits JAK2 autophosphorylation, induces apoptosis in a time- and dose-dependent manner, and can be used in lymph-derived diseases and leukemia research [1]....
MW: 325.15 D
From 1,440.00€ *
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12270 from 12274 pages