Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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PHGDH-IN-2
PHGDH-IN-2

Item number: TGM-T62232-100mg

Description: PHGDH-IN-2 is a potent NAD+-competitive PHGDH inhibitor (IC50: 5.2 µM) that exhibits inhibitory effects on the growth of PHGDH-dependent cancer cells and inhibits the serine synthesis pathway in [MDA-MB-468] cells. Target: Others
MW: 420.48 D
From 1,440.00€ *
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CDK-IN-9
CDK-IN-9

Item number: TGM-T62235-100mg

Description: CDK-IN-9 (compound 24) is a potent inhibitor of CDK and acts on CDK2/E (IC50: 4 nM). It functions as a molecular gel that induces interaction between CDK12 and DDB1, and can dephosphorylate retinoblastoma protein and RNA polymerase II, thereby inducing apoptosis. Target: Others
MW: 420.53 D
From 1,440.00€ *
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Steroid sulfatase/17beta-HSD1-IN-3
Steroid sulfatase/17beta-HSD1-IN-3

Item number: TGM-T62236-100mg

Description: Steroid sulfatase/17beta-HSD1-IN-3 (compound 19) is a dual inhibitor of steroid sulfatase (STS) and 17beta-hydroxysteroid dehydrogenase type 1 [17beta-HSD1], useful in studying endometriosis and other estrogen-dependent diseases. Target: Others
MW: 420.87 D
From 1,440.00€ *
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Steroid sulfatase-IN-4
Steroid sulfatase-IN-4

Item number: TGM-T62237-100mg

Description: Steroid sulfatase-IN-4 (Compound 16) is an irreversible inhibitor of human steroid sulfatase (STS) with an IC50 of 25 nM, and can be used to study endometriosis. Target: Others
MW: 420.87 D
From 1,440.00€ *
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Topo I/COX-2-IN-2
Topo I/COX-2-IN-2

Item number: TGM-T62241-100mg

Description: Topo I/COX-2-IN-2 (Compound W10) is a potent dual inhibitor of Topo I (IC50: 0.90 µM) and COX-2 (IC50: 2.31 µM), inducing apoptosis in cancer cells via the mitochondrial pathway. Target: Others
MW: 420.93 D
From 1,440.00€ *
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PPO-IN-1
PPO-IN-1

Item number: TGM-T62244-100mg

Description: PPO-IN-1 is a potent inhibitor of protoporphyrinogen IX oxidase (PPO) with a Ki of 2.5 nM. Target: Others
MW: 421.35 D
From 1,440.00€ *
Review
Chitin synthase inhibitor 8
Chitin synthase inhibitor 8

Item number: TGM-T62246-100mg

Description: Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal properties, suitable for research on fungal infections. Target: Others
MW: 421.45 D
From 1,440.00€ *
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R-HP210
R-HP210

Item number: TGM-T62252-100mg

Description: R-HP210 inhibits LPS-induced transcription of several pro-inflammatory genes (IL-1beta, IL-6 and COX-2). r-HP210 has an IC50 value of 3.80 µM for NF-kappaB-mediated bolus trans-suppression. r-HP210 does not induce trans-activation of glucocorticoids (GCs). Target: Others
MW: 421.54 D
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S-HP210
S-HP210

Item number: TGM-T62253-100mg

Description: S-HP210 is a selective and potent glucocorticoid receptor (GR) modulator that inhibits NF-kappaB transcription (IC50: 1.92 µM). S-HP210 is not toxic to mouse fibroblasts at effective doses of 3T3. Target: Others
MW: 421.54 D
From 934.00€ *
Review
Ten01
Ten01

Item number: TGM-T62257-100mg

Description: Ten01 exhibits a 5.0 nM inhibition of JAK1 kinase. Target: Others
MW: 422.37 D
From 1,440.00€ *
Review
GPR84 antagonist 1
GPR84 antagonist 1

Item number: TGM-T62261-100mg

Description: GPR84 antagonist 1 is a highly selective, high-affinity competitive antagonist of human GPR84. Target: Others
MW: 422.48 D
From 1,393.00€ *
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(+)-Sparteine sulfate pentahydrate
(+)-Sparteine sulfate pentahydrate

Item number: TGM-T62265-25mg

Description: (+)-Sparteine (sulfate pentahydrate) is a ganglion blocker that competitively inhibits nicotinic acetylcholine receptors in neurons. Target: Others
MW: 422.54 D
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Review
12251 from 12274 pages