Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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qsl-304
Item number: TGM-T79682-50mg
Description: QSL-304 is a DNA gyrase B inhibitor that serves as an antibacterial agent, exhibiting an IC50 of 31.23 mg/mL against Staphylococcus aureus SA-P2003 [1]. Target: DNA/RNA Synthesis
| MW: | 283.32 D |
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HDAC/CD13-IN-1
Item number: TGM-T79683-50mg
Description: HDAC/CD13-IN-1 (Compound 12) is an inhibitor of both HDAC and CD13, with IC50 values of 0.34 µM for hCD13, 0.53 µM for porcine CD13, and 0.03, 0.06, and 0.02 µM for HDAC1, HDAC2, and HDAC3, respectively. This compound effectively suppresses proliferation and induces apoptosis in MV4-11, K562, Jeko-1,...
| MW: | 570.55 D |
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5-HT6R antagonist 1
Item number: TGM-T79684-50mg
Description: Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability but also reverses MK-801-induced memory impairments in rats, suggesting its utility in Alzheimer's disease (AD) research [1]. Target: 5-HT Receptor
| MW: | 364.39 D |
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PI3Kalpha-IN-13
Item number: TGM-T79685-100mg
Description: PI3Kalpha-IN-13 (Compound 18a), a PI3Kalpha inhibitor with an IC50 of 2.5 nM, effectively induces apoptosis and hampers the proliferation of various cancer cell lines, exhibiting IC50 values of 0.75 µM (MCF-7), 3.79 µM (HCT-116), 13.71 µM (MDA-MB-231), and 9.85 µM (SW620). This compound also impedes...
| CAS | 2955529-67-4 |
| MW: | 389.41 D |
From 1,440.00€
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TEAD-IN-6
Item number: TGM-T79687-100mg
Description: TEAD-IN-6 (Example 11-1) is a TEAD modulator that inhibits the YAP1/TAZ-TEAD interaction and has applications in cancer research [1]. Target: YAP
| CAS | 2821763-12-4 |
| MW: | 438.42 D |
From 1,440.00€
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FAK-IN-11
Item number: TGM-T79688-50mg
Description: FAK-IN-11 (Compound 4l), a FAK inhibitor, specifically targets the ATP binding pocket of FAK to prevent its phosphorylation. It exhibits cytotoxic effects on MDA-MB-231 cells, achieving an IC50 value of 13.73 µM, and induces non-apoptotic cell death in these cells [1]. Target: FAK
| MW: | 403.6 D |
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FIKK9.1-IN-1
Item number: TGM-T79690-50mg
Description: FIKK9.1-IN-1 (Compound 1), an antimalarial agent (IC50: 2.68 µg/mL), serves as a FIKK9.1 inhibitor by interacting with the ATP-binding residues within FIKK9.1, thereby disrupting the parasite life cycle and resulting in parasite death [1]. Target: Parasite
| CAS | 1448523-50-9 |
| MW: | 393.38 D |
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AChE-IN-40
Item number: TGM-T79691-50mg
Description: AChE-IN-40 (Compound 5C), with an inhibitory concentration 50 (IC50) of 120 nM, is an acetylcholinesterase (AChE) inhibitor suitable for Alzheimer's disease research [1]. Target: Others
| MW: | 381.46 D |
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SIRT5 inhibitor 8
Item number: TGM-T78856-50mg
Description: SIRT5 inhibitor 8 (compound 10) is a competitive inhibitor of sirtuin SIRT5 with an IC50 of 5.38 µM and exhibits anticancer potential [1]. Target: Sirtuin
| MW: | 501 D |
From 1,070.00€
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SIRT5 inhibitor 9
Item number: TGM-T78857-50mg
Description: SIRT5 inhibitor 9 (compound 14), with an IC50 of 4.07 µM, is a competitive inhibitor of the sirtuin SIRT5, exhibiting potential anticancer properties [1]. Target: Sirtuin
| MW: | 561.06 D |
From 1,070.00€
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MAO-B-IN-23
Item number: TGM-T78859-100mg
Description: MAO-B-IN-23, also known as Compound 11f, is a reversible and competitive monoamine oxidase B (MAO-B) inhibitor with an IC50 value of 1.44 µM and a Ki of 0.51 µM [1]. Target: Monoamine Oxidase
| CAS | 2107978-22-1 |
| MW: | 356.26 D |
From 1,440.00€
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MAO-B-IN-24
Item number: TGM-T78860-50mg
Description: MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B with an IC50 value of 1.60 µM and an IC50 of 22.42 µM for MAO-A. At 10 µM concentration, it reduces AChE and BChE activities to 54.58% and 88.43%, respectively [1]. Target: Monoamine Oxidase
| MW: | 302.37 D |
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