Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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LM-41
Item number: TGM-T79427-50mg
Description: LM-41, a Flufenamic acid-derived TEAD inhibitor, significantly reduces the expression of CTGF, Cyr61, Axl, and NF2, and inhibits the migration of human MDA-MB-231 breast cancer cells [1]. Target: YAP
| MW: | 307.32 D |
From 171.00€
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AF-2112
Item number: TGM-T79428-50mg
Description: AF-2112, a TEAD inhibitor derived from Flufenamic acid, significantly diminishes the expression of CTGF, Cyr61, Axl, and NF2. Target: YAP
| MW: | 351.37 D |
From 743.00€
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Tubulin polymerization-IN-50
Item number: TGM-T79429-50mg
Description: Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 µM in SK-Mel-28 cells and inducing cell cycle arrest at the G2/M phase [1]. Target: Others
| MW: | 417.43 D |
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µ opioid receptor agonist 3
Item number: TGM-T79430-100mg
Description: Compound 20, identified as µ opioid receptor agonist 3, is a potent µOR agonist that exhibits an EC50 value of 0.87 nM. It holds promise for research into pain management and neuropsychiatric disorders [1]. Target: Opioid Receptor
| CAS | 2378397-91-0 |
| MW: | 352.47 D |
From 1,440.00€
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Mu opioid receptor antagonist 7
Item number: TGM-T79431-100mg
Description: Compound 24, also known as Mu opioid receptor antagonist 7, is a potent, centrally-acting µ-opioid receptor (µOR) antagonist with an inhibitory concentration (IC50) of 29 ± 3.0 nM. It is valuable for pain and opioid use disorder research [1]. Target: Opioid Receptor
| CAS | 2378397-30-7 |
| MW: | 386.91 D |
From 1,440.00€
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NXT-10796
Item number: TGM-T79432-50mg
Description: NXT-10796 is an orally active, intestinally restricted agonist of the EP4 receptor [1]. Target: Prostaglandin Receptor
| MW: | 445.51 D |
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AKR1C3-IN-10
Item number: TGM-T79433-50mg
Description: AKR1C3-IN-10 (compound 5r), a selective inhibitor of AKR1C3 with an IC50 of 51 nM, demonstrates efficacy in a prostate cancer xenograft model [1]. Target: Others
| MW: | 412.44 D |
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Antitumor agent-103
Item number: TGM-T79434-50mg
Description: Antitumor Agent-103 (compound 24l) induces apoptosis and possesses antiproliferative and anti-colony formation properties. This compound halts the cell cycle at the G0/G1 phase, augments nitric oxide (NO) production, and demonstrates anti-tumor efficacy [1]. Target: Apoptosis
| MW: | 788.85 D |
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Metallo-beta-lactamase-IN-11
Item number: TGM-T79435-50mg
Description: Metallo-beta-lactamase-IN-11 (compound 5f), a potent inhibitor of Metallo-beta-lactamases (MBLs), demonstrates efficacy against bacterial metallophyllactamase CphA with an IC50 value of 45 µM. At 10 µM, it inhibits NDM-1 by 49% and AIM-1 by 61%, indicating its potential for research on countering...
| MW: | 453.53 D |
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AHR agonist 4
Item number: TGM-T79436-50mg
Description: AHR agonist 4 (compound 24e), as an Aryl hydrocarbon receptor (AHR) agonist, modulates the immune equilibrium between Th17/22 and Treg cells. It is a lead compound under investigation for anti-psoriasis drugs and demonstrates efficacy in mitigating imiquimod (IMQ)-induced psoriasis-like skin lesions...
| MW: | 282.32 D |
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NAMPT degrader-3
Item number: TGM-T79437-50mg
Description: NAMPT Degrader-3 (compound C5) is a NAMPT degrader that functions through a VHL- and proteasome-dependent mechanism. It exhibits cytotoxic properties and inhibits the proliferation of A2780 cells [1]. Target: NAMPT
| MW: | 1003.3 D |
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c-Myc inhibitor 11
Item number: TGM-T79438-50mg
Description: c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50: 6.4), demonstrates high clearance, moderate volume of distribution, and a short half-life in rat pharmacokinetic assays, making it suitable for cancer research [1]. Target: c-Myc
| MW: | 362.43 D |
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