Products from TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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TH-263

Item number: TGM-T19578-200mg

Description: TH-263 is inactive toward both LIMK1 and LIMK2 and thus can be used as negative control for TH-257, and is a diaryl sulfonamide derivative. Target: Others. Smiles: S(NCC1=CC=CC=C1)(=O)(=O)C2=CC=C(C(NCC3=CC=CC=C3)=O)C=C2

MW:

380.46 D

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Semaglutide

Item number: TGM-T19850-200mg

Description: Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor). Target: Glucagon Receptor. Smiles:...

MW:

4114 D

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Indican

Item number: TGM-T19866-25mg

Description: Indican (Indoxyl-beta-D-glucoside) is a natural protective compound that is used to protect the liver. Target: OAT, MRP. Smiles: OC[C@H]1O[C@@H](Oc2c[nH]c3ccccc23)[C@H](O)[C@@H](O)[C@@H]1O

Keywords:	NSC-87517 , 3-Indoxyl-beta-D-glucopyranoside , NSC 87517 , NSC87517 , Indoxyl-beta-D-glucoside
MW:	295.29 D

30.00€ *

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EcDsbB-IN-9

Item number: TGM-T19925-200mg

Description: EcDsbB-IN-9 is a specific EcDsbB inhibitor, targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria. Target: Others. Smiles: Clc1cnn(Cc2ccccc2)c(=O)c1Cl

MW:

255.1 D

29.00€ *

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NEU3-IN-1

Item number: TGM-T200007-10mg

Description: NEU3-IN-2 (compound 963), a derivative of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) and a C9 biphenylcarbamate, functions as an inhibitor of NEU3, a human neuraminidase with four isozymes. This compound exhibits inhibitory activity with a Ki of 0.12 µM and an IC50 of 0.31 µM. It serves as a...

MW:

486.47 D

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Thalidomide-NH-cyclohexane-NH-Ph-NH2

Item number: TGM-T200010-10mg

Description: Thalidomide-NH-cyclohexane-NH-Ph-NH2, an E3 Ligase Ligand-Linker Conjugate, serves as a precursor for synthesizing PROTAC erf3a Degrader-2.

MW:

461.51 D

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Antiangiogenic agent 6

Item number: TGM-T200013-10mg

Description: Antiangiogenic agent 6 (Pt-1) effectively inhibits angiogenesis and induces necroptosis in tumor cells. Target: Apoptosis

MW:

850.66 D

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h15-LOX-2 inhibitor 2

Item number: TGM-T200017-10mg

Description: Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 µM and 16.4 µM, respectively. Target: Lipoxygenase

MW:

497.42 D

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BCL6 ligand-2

Item number: TGM-T200021-10mg

Description: BCL6ligand-2 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). It can be utilized in synthesis. Target: Ligands for Target Protein for PROTAC

MW:

494.58 D

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SMARCA2/4-ligand-3

Item number: TGM-T200026-10mg

Description: SMARCA2/4-ligand-3, a PROTAC target protein ligand (Ligands for Target Protein for PROTACs), is utilized in synthesis. Target: Ligands for Target Protein for PROTAC

MW:

514.51 D

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Antitumor photosensitizer-8

Item number: TGM-T200031-10mg

Description: Antitumor agent-187 (compound I3), a photosensitizer derived from 5,15-diarylporphyrin, exhibits anticancer activity with a peak absorption wavelength of ~668 nm. This compound induces apoptosis and is applicable in photodynamic therapy (PDP). It selectively accumulates in tumor sites and possesses...

MW:

810.85 D

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Epoxide hydrolase

Item number: TGM-T200049-10mg

Description: Epoxide hydrolase, an enzyme responsible for catalyzing the reaction of epoxides with water to convert epoxy groups into diols, plays a crucial role in the metabolism of environmental pollutants and lipids. It is instrumental in detoxification, inflammatory responses, and regulating the health of the...

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