Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
Item number: TGM-TMPK-00471-10ug
Description: Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor...
| Keywords: | MGC2463 , MGC104322 , LPD , C7orf15 , ALS2CR18 , PREL2 , ALS2CR9 , RMO1 , PREL-2 , RalGDS/AF-6 , CD112R , PVRIG , MGC138297 |
| MW: | 42.7 kD |
From 85.00€
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FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)
Item number: TGM-TMPK-00475-10ug
Description: FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.2 kDa and the accession number is A0A2K5TL84-1.
| Keywords: | BEK , FGFR2 beta (IIIb) , Keratinocyte growth factor receptor , Fibroblast growth factor receptor 2 , FGFR-2 , K-sam ,... |
| MW: | 26.2 kD |
From 55.00€
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RAGE Protein, Cynomolgus, Recombinant (His)
Item number: TGM-TMPK-00479-10ug
Description: The receptor for advanced glycation end products (AGER) is an oncogenic transmembranous receptor up-regulated in various human cancers. AGER promotes proliferation, migration, and inhibits apoptosis of squamous cervical cancer and might function as a tumor promoter in cervical cancer. Our study provides...
| Keywords: | AGER , RAGE , SCARJ1 |
| MW: | 36.78 kD |
From 55.00€
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E-selectin/CD62E Protein, Cynomolgus, Recombinant (aa...
Item number: TGM-TMPK-00487-10ug
Description: E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha.E-selectin mediates in the adhesion of blood neutrophils...
| Keywords: | selectin E , ELAM , ESEL , SELE , E-Selectin , LECAM2 , CD62E , ELAM1 |
| MW: | 59.47 kD |
From 55.00€
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IL-18BP Protein, Cynomolgus, Recombinant (His)
Item number: TGM-TMPK-00491-10ug
Description: Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity...
| Keywords: | Igifbp , Interleukin-18-binding protein , IL-18BP |
| MW: | 21.14 kD |
From 55.00€
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OSMR Protein, Cynomolgus, Recombinant (His)
Item number: TGM-TMPK-00493-10ug
Description: OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity,...
| Keywords: | OSMR , IL-31R subunit beta , OSMR beta , OSMRB , OSMRBMGC150626 , IL-31R subunit beta , OSMR beta , IL-31R-beta , IL-31RB... |
| MW: | 82.04 kD |
From 55.00€
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BSPII Protein, Cynomolgus, Recombinant (His)
Item number: TGM-TMPK-00498-10ug
Description: BSPII Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 34.63 kDa and the accession number is A0A2K5UM27.
| Keywords: | IBSP , SPII , BNSP , BSP-II , SP II , BSP , BSP II , BSP 2 , SP-II |
| MW: | 34.63 kD |
From 55.00€
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CD83 Protein, Cynomolgus, Recombinant (His)
Item number: TGM-TMPK-00500-10ug
Description: CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated immune cells, although it is most highly and stably expressed by mature dendritic cells (DC). While CD83 is emerging as a promising...
| Keywords: | CD83 , HB15 , CD83 molecule , BL11 |
| MW: | 15.43 kD |
From 55.00€
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PADI4 Protein, Cynomolgus, Recombinant (His)
Item number: TGM-TMPK-00501-10ug
Description: Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has...
| Keywords: | HL60 PAD , PAD , PDI5 , Protein-arginine deiminase type-4 , PADI5 , PAD4 , HL-60 , HL-60 PAD |
| MW: | 76.6 kD |
From 85.00€
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PADI4 Protein (Primary Amine Labeling), Cynomolgus,...
Item number: TGM-TMPK-00502-10ug
Description: Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has...
| Keywords: | PDI5 , HL-60 , PAD , PADI5 , Protein-arginine deiminase type-4 , HL60 PAD , PAD4 , HL-60 PAD |
| MW: | 76.6 kD |
From 108.00€
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BDCA-2 Protein, Cynomolgus, Recombinant (hFc)
Item number: TGM-TMPK-00504-10ug
Description: BDCA-2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 44.99 kDa and the accession number is A0A2K5UWP4.
| Keywords: | CD303 , BDCA-2 , DLEC , CLECSF7 , BDCA2 , CLECSF11 , CLEC4C , HECL |
| MW: | 44.99 kD |
From 55.00€
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TREM2 Protein, Cynomolgus, Recombinant (His)
Item number: TGM-TMPK-00507-10ug
Description: TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa...
| Keywords: | TREM2 , Trem2a , PLOSL2 , TREM-2 , Trem2c , Trem2b |
| MW: | 18.5 kD |
From 44.00€
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