Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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10582 from 11319 pages
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KDOAM-25 trihydrochloride
KDOAM-25 trihydrochloride

Item number: TGM-T62166-100mg

Description: KDOAM-25 trihydrochloride is a potent and highly selective inhibitor of histone lysine demethylase 5 (KDM5), targeting KDM5A (IC50: 71 nM), KDM5B (IC50: 19 nM), KDM5C (IC50: 69 nM), and KDM5D (IC50: 69 nM). It enhances overall H3K4 methylation at the transcription start site and hinders the...
MW: 416.77 D
From 1,440.00€ *
Review
Dual AChE-MAO B-IN-1
Dual AChE-MAO B-IN-1

Item number: TGM-T62172-100mg

Description: Dual AChE-MAO B-IN-1 (compound 15) is a safe, metabolically stable neuroprotective agent. This potent, orally active, CNS-permeable inhibitor demonstrates IC50 values of 550 nM for human AChE and 8.2 nM for MAO-B, indicating low in vitro activity against these enzymes. Target: Others
MW: 417.45 D
From 1,440.00€ *
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COX-2-IN-8
COX-2-IN-8

Item number: TGM-T62175-100mg

Description: COX-2-IN-8 (Compound 6a) is a potent, selective, orally active COX-2 inhibitor (IC50: 6.585 µM) with a higher COX-2 selectivity than Celecoxib. Target: Others
MW: 417.5 D
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TLR7/8 antagonist 1
TLR7/8 antagonist 1

Item number: TGM-T62178-100mg

Description: TLR7/8 Antagonist 1 (Compound 16c), an imidazoquinoline derivative, is a potent TLR7/8 agonist with IC50 values of 3.91 and 2.19 µM for TLR7 and TLR8, respectively. rel-O-2050 (TLR-2050) is a key target for drug development in infectious diseases, cancer, and autoimmune diseases. Target: Others
MW: 417.5 D
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ART615
ART615

Item number: TGM-T62186-100mg

Description: ART615 is a related isomer of ART558. ART615 inhibits Poltheta by <10% at 12 µM and is able to act as a control for ART558 (IC50:7.9 nM). Target: Others
MW: 418.41 D
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ATR-IN-12
ATR-IN-12

Item number: TGM-T62563-100mg

Description: ATR-IN-12 (Compound 5g) is a potent inhibitor of ataxia-capillaris and Rad3-related (ATR) kinase with an IC50 of 0.007 µM, making it a promising lead compound for further drug discovery studies on ATR kinases. Target: Others
MW: 441.55 D
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CDK2-IN-9
CDK2-IN-9

Item number: TGM-T62567-100mg

Description: CDK2-IN-9 is a potent CDK2 inhibitor (IC50: 0.63 µM) with anti-proliferative effects, capable of blocking the cell cycle in S and G2/M phases and inducing apoptosis, showing potential for melanoma research. Target: Others
MW: 441.89 D
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Antileishmanial agent-6
Antileishmanial agent-6

Item number: TGM-T62574-100mg

Description: Antileishmanial agent-6 is a potent anti-leishmanial agent with anti-leishmanial activity (IC50: 0.54 µM) and cytotoxicity (IC50: 10.2 µM) against Leishmania donovani and L-6. Target: Others
MW: 442.46 D
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Anti-ToCV agent 1
Anti-ToCV agent 1

Item number: TGM-T62575-100mg

Description: Anti-ToCV agent 1 [AIDA] can be used as a potential anti-ToCV drug. Target: Others
MW: 442.46 D
From 1,440.00€ *
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CBR Agonist-1
CBR Agonist-1

Item number: TGM-T62583-100mg

Description: CBR Agonist-1 (27a-cis) is a cannabinoid receptor (CBR) agonist that targets CB1R with a Ki of 0.18 µM and CB2R with a Ki of 1.22 µM. It can be utilized to investigate diseases related to the endogenous cannabinoid system. Target: Others
MW: 442.53 D
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CBR Agonist-2
CBR Agonist-2

Item number: TGM-T62584-100mg

Description: CBR Agonist-2 is a CB1 agonist (CB1R, CB1 ligand) with an EC50 of 960 nM and Ki of 970 nM, making it a promising tool for studying diseases related to the endogenous cannabinoid system involving hCB1R. Target: Others
MW: 442.53 D
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Cav 2.2/3.2 blocker 1
Cav 2.2/3.2 blocker 1

Item number: TGM-T62586-100mg

Description: Cav 2.2/3.2 blocker 1 (Compound 9e) is a neuronal calcium channel blocker with IC50 values of 1.22 µM for Cav2.2 and 80 µM for Cav3.2, capable of penetrating the central nervous system. Target: Others
MW: 442.55 D
From 1,440.00€ *
Review
10582 from 11319 pages