Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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KAT modulator-1
Item number: TGM-T79131-2mg
Description: KAT modulator-1 (Compound 3), an epigenetics research tool, selectively interacts with the full-length p300 protein but not its catalytic domain [1]. Target: Histone Acetyltransferase
| CAS | 1314006-43-3 |
| MW: | 308.5 D |
132.00€
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Du011
Item number: TGM-T79132-50mg
Description: Du011 is a biogenesis inhibitor of the E. coli polysaccharide capsule that specifically targets MprA, with potential applications in E. coli infection research [1]. Target: Others
| CAS | 890818-51-6 |
| MW: | 403.4 D |
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FEN1-IN-6
Item number: TGM-T79134-50mg
Description: FEN1-IN-6 (compound 9) is a potent Flap endonuclease-1 (FEN1, IC50 = 10 nM) inhibitor, crucial for DNA damage repair in mammalian cells, and also targets the related endonuclease xeroderma pigmentosum G (XPG) with an IC50 of 23 nM [1]. Target: FLAP
| CAS | 824983-84-8 |
| MW: | 324.33 D |
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FEN1-IN-7
Item number: TGM-T79135-50mg
Description: FEN1-IN-7 (compound 16), a selective Flap endonuclease-1 (FEN1) inhibitor with an IC50 of 18 nM, plays a role in DNA damage repair in mammalian cells. Additionally, it targets the related endonuclease, xeroderma pigmentosum G (XPG), with an IC50 of 3.04 µM. FEN1-IN-7 enhances the sensitivity of cancer...
| CAS | 824983-90-6 |
| MW: | 362.36 D |
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DGKzeta-IN-1
Item number: TGM-T79136-100mg
Description: DGKzeta-IN-1 (compound 9) is a DGKzeta inhibitor with potential applications in cancer research, particularly for studying immunocyte activation and resistance to anti-PD-1/anti-PD-L1 antibody therapies [1]. Target: Others
| CAS | 2660218-70-0 |
| MW: | 554.59 D |
From 1,440.00€
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Monlunabant
Item number: TGM-T79137-5mg
Description: Monlunabant ((S)-MRI-1891), a solid dispersion compound, functions as an inhibitor of the cannabinoid CB1 receptor [1]. Target: Cannabinoid Receptor
| Keywords: | (S)-MRI-1891 |
| CAS | 2712480-46-9 |
| MW: | 591 D |
918.00€
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Antitumor agent-100 hydrochloride
Item number: TGM-T79138-50mg
Description: Antitumor agent-100 hydrochloride (compound A6), serving as both an apoptosis inducer and molecular glue, exhibits superior anti-tumor activity [1]. Target: Molecular Glues
| CAS | 2841750-53-4 |
| MW: | 348.23 D |
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GBD-9
Item number: TGM-T79139-50mg
Description: GBD-9, a dual-mechanism degrader, effectively promotes the degradation of BTK and GSPT1 through recruitment of E3 ligase cereblon (CRBN). As a PROTAC molecule, GBD-9 induces BTK degradation, while also acting as a molecular glue for GSPT1 degradation, demonstrating potent inhibition of cancer cell...
| CAS | 2864408-92-2 |
| MW: | 797.9 D |
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alphavbeta6 integrin inhibitor 2
Item number: TGM-T79140-50mg
Description: alphavbeta6 Integrin Inhibitor 2 is a potent inhibitor of alphavbeta6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM. Target: Integrin
| Application: | alphavbeta6 integrin inhibitor |
| CAS | 313709-47-6 |
| MW: | 386.49 D |
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Mosnodenvir
Item number: TGM-T79141-100mg
Description: Mosnodenvir (JNJ-1802), a pan-serotype dengue antiviral agent, exhibits picomolar to low nanomolar in vitro activity with a high barrier to resistance and is safe and well-tolerated in murine models [1] [2]. It functions by blocking the NS3-NS4B interaction within the viral replication complex. Target:...
| Keywords: | JNJ-1802 |
| CAS | 2890688-86-3 |
| MW: | 582.98 D |
From 3,766.00€
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c-Met-IN-17
Item number: TGM-T79142-50mg
Description: c-Met-IN-17 is a potent inhibitor of c-Met kinase with an IC50 of 0.031 µM, making it relevant for anticancer research. [1]. Target: c-Met/HGFR
| MW: | 374.37 D |
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MS934
Item number: TGM-T79143-50mg
Description: MS934, a novel VHL-recruiting MEK 1/2 degrader, exhibits potent anti-proliferative effects on HT-29 cell growth, achieving a GI50 of 0.023 µM. It holds potential for researching various human cancers including melanoma, non-small cell lung cancer (NSCLC), colorectal cancer, primary brain tumors, and...
| CAS | 2756323-15-4 |
| MW: | 1104.11 D |
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