Products from TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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VISTA-IN-3

Item number: TGM-T87620-10mg

Description: VISTA-IN-3 (Compound A4), a potent small molecule inhibitor of VISTA, exhibits a dissociation constant (K D) of 0.49 µM. This compound effectively induces the release of IFN-gamma cytokines and demonstrates synergistic enhancement of anti-cancer activity when combined with PD-L1 antibody [1]. Target:...

MW:

290.32 D

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WSD0628

Item number: TGM-T87636-10mg

Description: WSD0628 is a brain-penetrant and potent ATM inhibitor with a significant radiosensitizing effect [1]. Target: ATM/ATR. Smiles: O=C1N(C=2C=3C(N=CC2N1C)=CC=C(C3)C=4C=CC(OC)=NC4)[C@H]5C(F)(F)CN(C)CC5

MW:

439.46 D

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Kamuvudine-8

Item number: TGM-T85346-100mg

Description: Kamuvudine-8 (K8) is a zidovudine (AZT) derivative that can be used to study diabetic macular edema. Target: Others. Smiles: CCn1c(=O)c(C)cn(C2CC(N=[N+]=[N-])C(COC)O2)c1=O

MW:

309.32 D

From 178.00€ *

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Cinepazet

Item number: TGM-T85350-100mg

Description: Cinepazet is a vasodilator that can be used to study cardiovascular disease. Target: Others. Smiles: O=C(OCC)CN1CCN(C(=O)C=CC2=CC(OC)=C(OC)C(OC)=C2)CC1. References: Levy JV. Cinepazet relaxation of aortic strips from normal and spontaneously hypertensive rats. Res Commun Chem Pathol Pharmacol. 1980...

MW:

392.45 D

From 54.00€ *

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BI-4732

Item number: TGM-T85354-1mg

Description: BI-4732 is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with high blood-brain barrier permeability, antitumor activity, inhibition of EGFR activation, and inhibition of T790M mutations. Target: EGFR. Smiles:...

Keywords:	BI4732
MW:	592.69 D

From 304.00€ *

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2-(Naphthalen-2-yl)acetic acid

Item number: TGM-T85397-10mg

Description: 2-(Naphthalen-2-yl)acetic acid (2-Naphthylacetic acid), functions as a plant growth regulator and acts as an antagonist to 3-Indoleacetic acid [1]. Smiles: O=C(O)CC=1C=CC=2C=CC=CC2C1

Keywords:	2-Naphthylacetic acid
MW:	186.21 D

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2,6-Diiodo-BODIPY 493/503

Item number: TGM-T85401-5mg

Description: 2,6-Diiodo-BODIPY 493/503, a fluorescent F-Bodipy dye, features a diiodo substitution at the (pyrrole) 2,6 position. This pyrrole iodine substituent imparts a red hue to the compound [1]. Target: Others. Smiles: [F-][B+3]1([F-])[N]=2C(C(=C(I)C2C)C)=C(C3=C(C(I)=C([N-]31)C)C)C

Keywords:	2,6-Diiodo-BDP 493/503 lipid stain , 2,6-Diiodo-Pyrromethene 546
MW:	513.9 D

30.00€ *

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Fabl inhibitor 21272541

Item number: TGM-T85407-100mg

Description: 21272541 is a potent FabI protein inhibitor that significantly reduces infections caused by Gram-negative organisms [1]. Target: Antibacterial. Smiles: ClC1=CC=C(OC2=CC=C(Cl)C=C2O)C(O)=C1

MW:

271.1 D

From 1,440.00€ *

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25N-N1-Nap

Item number: TGM-T85409-10mg

Description: Compound 16, also known as 25N-N1-Nap, functions as a beta-arrestin-biased 5-HT2A agonist. It effectively antagonizes phencyclidine-induced hyperactivity in male C57BL/6J mice [1]. Target: 5-HT Receptor. Smiles: O=N(=O)C1=CC(OC)=C(C=C1OC)CCNCC2=CC=CC=3C=CC=CC32

MW:

366.41 D

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