Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Tween 80
Item number: TGM-T13947-100mL
Description: Tween 80 is a nonionic surfactant and emulsifier that reduces bacterial adherence and inhibits biofilm formation. Tween 80 is widely used as a co-solvent in pharmacology experiments because of its ability to enhance the solubility of compounds in the aqueous phase. Target: Others. References: Nielsen...
| Application: | Pharmaceutic aid (surfactant) |
| CAS | 9005-65-6 |
46.00€
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PF-06305591
Item number: TGM-T12424-5mg
Description: PF-06305591 is an effective and selective blocker of voltage-gated sodium channel NaV1.8 (IC50 = 15 nM). Target: Others. Smiles: C[C@H]([C@H](N)c1nc2cc(ccc2[nH]1)C(C)(C)C)C(N)=O. References: Brown AD, et al. The discovery and optimization of benzimidazoles as selective NaV1.8 blockers for the treatment...
| Keywords: | PF-6305591 |
| CAS | 1449473-97-5 |
| MW: | 274.36 D |
From 42.00€
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SB-431542
Item number: TGM-T1726-5mg
Description: SB-431542 is an inhibitor of ALK5/TGF-beta type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiation of stem cells. Target: TGF-beta/Smad, ALK. Smiles:...
| Keywords: | SB 431542 |
| Application: | Smad3 phosphorylation inhibitor, TGFBR1/ALK4/ALK7 kinase inhibitor |
| CAS | 301836-41-9 |
| MW: | 384.39 D |
From 48.00€
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Vorinostat
Item number: TGM-T1583-200mg
Description: Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11. Vorinostat has antitumor activity, induces cell differentiation, blocks the cell cycle and induces apoptosis. Target: Virus Protease, Apoptosis, Autophagy, HDAC, Mitophagy....
| Keywords: | SAHA, MK0683, suberoylanilide hydroxamic acid |
| Application: | Antineoplastic, Histone deacetylase inhibitor |
| CAS | 149647-78-9 |
| MW: | 264.32 D |
From 42.00€
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N-Acetylneuraminic acid
Item number: TGM-T1638-1g
Description: N-Acetylneuraminic acid (Acide aceneuramique) is a nine-carbon sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies have shown that N-Acetylneuraminic acid is biologically useful for neurotransmission, leukocyte...
| Keywords: | NeuAc, Lactaminic acid, Acide aceneuramique |
| Application: | Myopathy treatment |
| CAS | 131-48-6 |
| MW: | 309.27 D |
From 43.00€
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TAK-243
Item number: TGM-T16974-5mg
Description: TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM), blocking ubiquitin binding and disrupting both mono-ubiquitin signaling and overall protein ubiquitination. TAK-243 exhibits antitumor activity and promotes apoptosis. Target: Apoptosis, E1/E2/E3 Enzyme,...
| Keywords: | MLN7243 |
| Application: | Ubiquitin-like modifier-activating enzyme 1 (UBA1) inhibitor |
| CAS | 1450833-55-2 |
| MW: | 519.52 D |
From 39.00€
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Candesartan
Item number: TGM-T1461-10mg
Description: Candesartan (CV 11974) is an angiotensin II receptor blocker widely used in the treatment of hypertension and heart failure. Target: RAAS. Smiles: CCOc1nc2cccc(C(=O)O)c2n1Cc1ccc(cc1)c1ccccc1c1n[nH]nn1. References: Fierens F, et al. Eur J Pharmacol, 1999, 367(2-3), 413-422.
| Keywords: | CV 11974 |
| Application: | Targets angiotensin II receptor type 1 (AGTR1) |
| CAS | 139481-59-7 |
| MW: | 440.47 D |
From 48.00€
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Gemifloxacin mesylate
Item number: TGM-T1492-10mg
Description: Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually bacterial growth. Gemifloxacin Mesylate is the mesylate salt form of gemifloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial...
| Keywords: | LB-20304a, SB-265805S, Gemifloxacin mesylate |
| Application: | Antibacterial, Nucleic acid biosynthesis inhibitor |
| CAS | 210353-53-0 |
| MW: | 485.49 D |
From 30.00€
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Amiodarone hydrochloride
Item number: TGM-T1496-500mg
Description: Amiodarone hydrochloride (Amiodarone HCl) is an antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance....
| Keywords: | Amiodar, Amiodarone HCl, Nexterone |
| Application: | Targets potassium voltage-gated channel Shal-related subfamily D member 3 (KCND3, KV4.3) |
| CAS | 19774-82-4 |
| MW: | 681.78 D |
From 35.00€
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DiI
Item number: TGM-T15129-10mg
Description: DiI (DiIC18(3)) is a lipophilic membrane dye commonly used as a long-term tracer for neurons and other cells. DiI fluoresces very weakly before it enters the cell membrane, and only after it enters the cell membrane can it be excited to emit a strong orange-red fluorescence (lambdaex=549 nm,...
| Keywords: | DiIC18(3) |
| CAS | 41085-99-8 |
| MW: | 933.87 D |
From 29.00€
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DSG Crosslinker
Item number: TGM-T15171-500mg
Description: DSG Crosslinker, a cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs). Target: Others, ADC Linker. Smiles: O=C(CCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O. References: Geng X, et al. Synthesis of the Oligosaccharides of Burkholderia pseudomallei and B. mallei Capsular...
| CAS | 79642-50-5 |
| MW: | 326.26 D |
From 38.00€
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DSP-2230
Item number: TGM-T15174-10mg
Description: DSP-2230 is a selective blocker of Nav1.7/Nav1.8. Target: Sodium Channel. Smiles: C[C@H](NCc1nc2ccc(Oc3cc(F)c(F)c(F)c3)nc2n1C1CCC1)C(N)=O. References: Bagal SK, et al. Voltage gated sodium channels as drug discovery targets. Channels (Austin). 2015,9(6):360-6.
| CAS | 1233231-30-5 |
| MW: | 419.4 D |
From 30.00€
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