Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Beta-Sitosterol
Item number: TGM-T2966-10mg
Description: Beta-Sitosterol (SKF 14463) has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. Beta-Sitosterol (SKF 14463) , a main dietary phytosterol found in plants, may have the potential for prevention and therapy for human cancer....
| Keywords: | Cupreol , Beta-Sitosterol , beta-Sitosterol , Azuprostat , SKF 14463 , 22,23-Dihydrostigmasterol , Betaprost |
| MW: | 414.71 D |
From 30.00€
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Gel4 Protein, Neosartorya fumigata, Recombinant (His)
Item number: TGM-TMPH-03050-5ug
Description: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in cell wall...
| Keywords: | 3-beta-glucanosyltransferase gel4 , Glucan elongating glucanosyltransferase 4 , gel4 , 1,3-beta-glucanosyltransferase gel4 |
| MW: | 55.4 kD |
From 134.00€
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Tryptamine hydrochloride
Item number: TGM-T124997-10g
Description: Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1 and AHR, with potential for blood-brain barrier permeability. Target: Endogenous Metabolite, 5-HT Receptor, AhR. Smiles: Cl.NCCC1=CNC=2C=CC=CC21
| Keywords: | 3-(2-Aminoethyl)indole~2-(3-Indolyl)ethylamine HCl |
| MW: | 196.68 D |
From 29.00€
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Phosphoribosyl pyrophosphate pentasodium
Item number: TGM-T38472-1mg
Description: Phosphoribosyl pyrophosphate pentasodium is the sodium salt form of PRPP. PRPP is a phosphoribosyl donor for AMP and GMP synthesis in reactions catalysed by adenine phosphoribosyltransferase and hypoxanthine/guanine phosphoribosyltransferase. PRPP is synthesized from ribose-5-phosphate and ATP by PRPP...
| Keywords: | PRPPpentasodium , PRPP pentasodium |
| MW: | 499.98 D |
From 51.00€
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DiSC3(5)
Item number: TGM-T67628-25mg
Description: DiSC3(5) is a lipophilic cationic fluorescent probe sensitive to changes in membrane potential. 3,3'-Dipropylthiadicarbocyanine iodide accumulates in hyperpolarized cell membranes, leading to fluorescence quenching, when the membranes are depolarized, the dye is released from the cells and the...
| Keywords: | 3,3'-Dipropylthiadicarbocyanine iodide |
| MW: | 546.53 D |
From 39.00€
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Astragalin
Item number: TGM-T6S1101-25mg
Description: Astragalin (Kaempferol 3-O-glucoside) is a biologically active natural flavonoid. It has a variety of pharmacological properties, including antioxidant, anti-inflammatory, anti-cancer, neuroprotective, and cardioprotective properties. Target: NF-kappaB, Apoptosis. Smiles:...
| Keywords: | Kaempferol 3-D-glucoside , Kaempferol 3-O-glucoside , kaempferol-3-glucoside , 3-Glucosylkaempferol , Astragaline ,... |
| MW: | 448.38 D |
From 30.00€
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(4-Aminobenzoyl)-D-glutamic acid
Item number: TGM-T204263-10mg
Description: (4-Aminobenzoyl)-D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against the H2-pterin synthesis system, affecting folic acid synthesis and subsequently inhibiting bacterial growth. Target: Antibacterial, Others. Smiles: C(N[C@H](CCC(O)=O)C(O)=O)(=O)C1=CC=C(N)C=C1
| MW: | 266.25 D |
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VEGFR-2-IN-64
Item number: TGM-T204271-10mg
Description: VEGFR-2-IN-64 (Compound 28) is an inhibitor of VEGFR2 with an IC50 of 27.8 nM. It suppresses the proliferation of cancer cells A549, T-47D, and Caco-2, exhibits anti-migration and anti-colony formation activities in T-47D cells, and induces apoptosis in T-47D cells. Target: Apoptosis, VEGFR. Smiles:...
| MW: | 1210.8 D |
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BMS-214662 mesylate
Item number: TGM-T204276-10mg
Description: BMS-214662 mesylate is a potent and selective farnesyl transferase inhibitor with an IC50 of 1.35 nM. It exhibits antitumor activity and is applicable in cancer research. Target: Transferase. Smiles: S(C)(=O)(=O)O.C([C@H]1N(S(=O)(=O)C2=CC=CS2)CC=3C(N(CC4=CN=CN4)C1)=CC=C(C#N)C3)C5=CC=CC=C5
| MW: | 585.718 D |
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Desthiazolylmethyl ritonavir
Item number: TGM-T204277-10mg
Description: Desthiazolylmethyl ritonavir is an alkaline-catalyzed degradation product of the HIV protease inhibitor Ritonavir. Target: HIV Protease. Smiles: C([C@H](CC1=CC=CC=C1)NC([C@@H](NC(N(CC=2N=C(C(C)C)SC2)C)=O)[C@H](C)C)=O)[C@H]3[C@H](CC4=CC=CC=C4)NC(=O)O3
| MW: | 605.791 D |
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AK-968-11563024
Item number: TGM-T204280-10mg
Description: AK-968-11563024 is an inhibitor targeting marine V. vulnificus NAT [(VIBVN)NAT] with an IC50 value of 18.86 µM. In V. vulnificus, NAT (aromatic amine N-acetyltransferase) plays a role in drug metabolism, contributing to drug resistance. Thus, AK-968-11563024 can be used for research related to drug...
| MW: | 689.162 D |
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Doxazosin impurity 12
Item number: TGM-T204282-10mg
Description: Doxazosin impurity 12 acts as an inhibitor of CTX-M beta-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M. Target: Antibacterial, Beta-lactamase. Smiles: O=C1C=C(C=2C=CC=CC2C1=O)S(=O)(=O)O
| MW: | 238.217 D |
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