Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Estrone
Item number: TGM-T1009-1g
Description: Estrone (Aquacrine) is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENE DIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and...
| Keywords: | Fluoroethyl, Oestrone, Aquacrine |
| CAS | 53-16-7 |
| MW: | 270.37 D |
From 44.00€
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Vigabatrin
Item number: TGM-T0128-25mg
Description: Vigabatrin (Sabril), an analogue of gamma-aminobutyric acid, is an irreversible inhibitor of 4-aminobutyrate Transaminase responsible for the catabolism of gamma-aminobutyric acid. Target: ABC, GABA Receptor. Smiles: NC(CCC(O)=O)C=C. References: Tyacke RJ, et al. Adv Pharmacol. 2010,58:373-96.
| Keywords: | Vigabatrine, Sabril |
| CAS | 60643-86-9 |
| MW: | 129.16 D |
From 42.00€
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Miglustat
Item number: TGM-T12039-100mg
Description: Miglustat (NB-DNJ) is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1). Target: Others. Smiles: Cl.CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO. References: Abian, O., et al., Therapeutic strategies for...
| Keywords: | NB-DNJ, OGT918, N-Butyldeoxynojirimycin |
| Application: | Targets ceramide glucosyltransferase [EC:2.4.1.80] (UGCG) |
| CAS | 72599-27-0 |
| MW: | 219.28 D |
From 37.00€
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Misoprostol acid
Item number: TGM-T12047-1mg
Description: Misoprostol acid, an active metabolite of Misoprostol, is used for treating non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers. Target: Others. Smiles: CCCCC(C)(O)CC=CC1C(O)CC(=O)C1CCCCCCC(O)=O. References: Vijaya Bharathi D, et al. Development and validation of highly sensitive method...
| CAS | 112137-89-0 |
| MW: | 368.51 D |
From 187.00€
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Tinidazole
Item number: TGM-T0893-500mg
Description: Tinidazole (CP12574)a is a 5-nitroimidazole derivative with the antiprotozoal property. Although the mechanism of action has not been fully elucidated, it has been suggested that tinidazole is metabolized and yields nitrite anions and metronidazole. Metronidazole's nitro group, in turn, is reduced via...
| Keywords: | CP12574 |
| CAS | 19387-91-8 |
| MW: | 247.27 D |
From 30.00€
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Vimseltinib
Item number: TGM-T10652-10mg
Description: Vimseltinib (DCC-3014) is a dual inhibitor targeting c-FMS (CSF-IR) and c-Kit with IC50 values of less than 0.01 µM and 0.1-1 µM, respectively. Target: c-Kit, CSF-1R, c-Fms. Smiles: CC(C)Nc1ncc(-c2ccc(Oc3ccnc(c3)-c3cnn(C)c3)c(C)n2)c(=O)n1C. References: Yumi Ahn, et al. 2-aminopyrimidin-6-ones and...
| Keywords: | DCC-3014 |
| CAS | 1628606-05-2 |
| MW: | 431.49 D |
From 79.00€
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Glutathione oxidized
Item number: TGM-T1085L-1g
Description: Glutathione oxidized (L(-)-Glutathione) is a GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized. Target: Endogenous Metabolite, Reactive Oxygen Species, Glutathione reductase. Smiles:...
| Keywords: | L(-)-Glutathione, GSSG, Glutathione disulfide, L-Glutathione oxidized, Oxidized glutathione, Bi(glutathion-S-yl) |
| CAS | 27025-41-8 |
| MW: | 612.63 D |
From 38.00€
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L-Tyrosine
Item number: TGM-T0493-100mg
Description: L-Tyrosine ((S)-Tyrosine) is a naturally occurring tyrosine and is synthesized in vivo from L-phenylalanine, considered a non-essential amino acid. L-Tyrosine(L-p-Tyrosine) is the levorotatory isomer of the aromatic amino acid tyrosine. Target: Endogenous Metabolite, Amino Acids and Derivatives....
| Keywords: | Tyrosine, P-Tyrosine, (S)-Tyrosine, L-p-Tyrosine |
| CAS | 60-18-4 |
| MW: | 181.19 D |
From 37.00€
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GLPG0492
Item number: TGM-T11410L-10mg
Description: GLPG0492 is a novel selective androgen receptor modulator. After oral dosing, it showed anabolic activity on muscle, strongly dissociated from the androgenic activity on the prostate. Target: Androgen Receptor. Smiles: CN1C(=O)N(C(=O)[C@@]1(CO)c1ccccc1)c1ccc(C#N)c(c1)C(F)(F)F. References: Nique F, et...
| CAS | 1215085-92-9 |
| MW: | 389.33 D |
From 65.00€
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Pentosan Polysulfate
Item number: TGM-T12420-500mg
Description: Pentosan Polysulfate is a potent and selective anti-HIV agent.with anti-inflammatory and pro-chondrogenic properties,and used for treatment of interstitial cystitis. Target: HIV Protease. References: Schuchman EH, et al. Pentosan polysulfate: a novel therapy for the mucopolysaccharidoses. PLoS One....
| CAS | 37300-21-3 |
278.00€
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Cabergoline
Item number: TGM-T14853-1mg
Description: Cabergoline (FCE-21336) is an ergot derived-dopamine D2-like receptor agonist. It has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).Cabergoline permits rapid and effective hormonal and tumor control by normalizing prolactin-producing pituitary adenomas levels....
| Keywords: | FCE-21336 |
| Application: | Targets dopamine receptor D2 (DRD2) |
| CAS | 81409-90-7 |
| MW: | 451.6 D |
From 33.00€
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Nitrosoglutathione
Item number: TGM-T19930-50mg
Description: Nitrosoglutathione (GSNO) is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins. GSNO, an exogenous NO donor and substrate of rat alcohol dehydrogenase class III isoenzyme, inhibits cerebral angiotensin II-dependent and -independent AT1 receptor responses....
| Keywords: | GSNO, SNOG, S-Nitrosoglutathione, Glutathione thionitrite |
| CAS | 57564-91-7 |
| MW: | 336.32 D |
From 46.00€
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