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Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. The NCOR2 antibody targets Nuclear receptor corepressor 2, a transcriptional regulator encoded by the NCOR2 gene. Also known as silencing mediator for retinoid and thyroid hormone receptors (SMRT), this large nuclear protein functions as a...

Protein function: Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the...

Protein function: Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the...

Protein function: Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-312aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MSGSTQPVAQ TWRATEPRYP PHSLSYPVQI ARTHTDVGLL EYQHHSRDYA SHLSPGSIIQ PQRRRPSLLS EFQPGNERSQ ELHLRPESHS YLPELGKSEM EFIESKRPRL ELLPDPLLRP SPLLATGQPA GSEDLTKDRS...

Protein function: Transcriptional corepressor (PubMed:20812024). Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 4 have different affinities for different nuclear receptors....

Protein function: Transcriptional corepressor (PubMed:20812024). Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 4 have different affinities for different nuclear receptors....

Nuclear receptor corepressor 2 (NcoR2) is a transcriptional corepressor that plays an essential role in the regulation of development and metabolism. Histone deacetylases (HDACs) can mediate nuclear receptor functions by forming co-repressor complexes with nuclear receptors in the absence of ligands. However, HDACs...

NcoR2 (nuclear receptor co-repressor) is a transcriptional corepressor that plays an essential role in the regulation of development and metabolism. The interaction of HDAC3 with the deacetylase activation domain (DAD) of NCOR2/SMRT is required for activation of the otherwise inert deacetylase. Recombinant human...

Sample Type:, Cell lysate, Intended Use: The NCOR2 DNA-Binding ELISA Kit qualitatively detects endogenous NCOR2 protein. Range: 10-30ug of total protein/well, Assay Time: 6 hours, Reactivity: Human, Mouse, Rat, Detection Method: Colorimetric 450 nm, Format: DNA-Binding ELISA, Storage and Stability: Store powder at...

Protein function: Transcriptional corepressor (PubMed:20812024). Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 4 have different affinities for different nuclear receptors....