Anti-PAN-SHANK Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with SHANK from human, mouse, and rat based on 100% homology with the immunizing sequence. Recognzies Shank1, 2 and 3. Cross-reactivity with Shank from other sources has not been determined....

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all , biological cells because their main function is...

Protein function: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization...