92 products were found matching "Q9NYJ7"!

Rovalpituzumab is a humanized monoclonal antibody against delta like protein 3 (DLL3). Rovalpituzumab can be used in the synthesis of the antibody-drug conjugate (ADC) Rovalpituzumab Tesirine. DLL3, also known as delta like ligand three, is a Notch ligand characterized by a DSL domain, transmembrane region, and a...

FZ-A038 is a delta-like ligand 3 (DLL3) targeted, humanized monoclonal antibody. FZ-A038 can be used for synthesis of the DLL3 targeting ADC (antibody drug conjugate) FZ-AD005 (BPS Bioscience #84250). DLL3, also known as delta like ligand three, is a Notch ligand characterized by a DSL domain, transmembrane region,...

Protein function: Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity) [The UniProt Consortium]

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human dLL3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human dLL3. Next,...

DLL3 Knockout SHP-77 Cell line is a human small cell lung cancer (SCLC) cell line, in which DLL3 (Delta-like canonical Notch ligand 3) is not expressed due to CRISPR/Cas9 genome editing. This cell line was validated by flow cytometry. Small cell lung cancer (SCLC), an aggressive form of cancer, accounts for about...

Delta-like protein 3 (DLL3), as a ligand of the Notch pathway, is specifically and highly expressed on the surface of SCLC (small cell lung cancer) cells. It plays an important role in tumor initiation, epithelial-mesenchymal transition, invasion and metastasis of SCLC. Inhibits primary neurogenesis. May be required...

DLL3 (Delta-like protein 3) Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles ready to transduce nearly all types of mammalian cells, including primary and non-dividing cells. These particles contain human DLL3 (NM_016941.3) driven by a CMV promoter and a puromycin selection...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Delta-like 3 is a protein which in humans is encoded by the DLL3 gene. This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutation...

In 1X PBS, pH 7.4, with 0.09% sodium azide. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). [UniProt] Protein function: Inhibits primary...

CHO-K1 cells expressing human delta like canonical Notch ligand 3 (DLL3) gene (accession number NM_016941.3) under the control of the cytomegalovirus (CMV) promoter. This cell line was generated by lentiviral transduction followed by puromycin selection and limited dilution. Individual clones were screened based on...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human dLL3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human dLL3. Next,...

Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 27-492aa. Protein Length: Extracellular Domain. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: AGVFELQIHS FGPGPGPGAP RSPCSARLPC RLFFRVCLKP GLSEEAAESP CALGAALSAR GPVYTEQPGA PAPDLPLPDG LLQVPFRDAW PGTFSFIIET WREELGDQIG GPAWSLLARV AGRRRLAAGG...