Anti-Olig2 antibody is directed against mouse Olig2 protein. The antibody is Protein A purified. This antibody is suitable for immunohistochemistry and immunocytochemistry. Reactivity is expected against human and rat. Cross reactivity with Olig2 from other species has not been determined. Protein function: Required...

Oligodendrocyte lineage transcription factor 2 (Olig2) is a basic helix-loop-helix transcription factor that is essential to the formation of oligodendrocytes and motor neurons in the spinal cord and somatic motor neurons in the hindbrain. It represses differentiation and sustains the replication competent state of...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Protein function: Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain (PubMed:11955448, PubMed:12121626, PubMed:16908628). Functions together with ZNF488 to promote oligodendrocyte differentiation (PubMed:16908628)....