114 products were found matching "Q96EB6"!

Active, full-length human SIRT1 (AA 1-747) protein expressed and purified from Baculovirus infected insect cells with a C-Terminal His tag. The enzyme has been thoroughly validated with the Transcreener OAADPr Assay Kit. For specific activity, please refer to the Certificate of Analysis for each individual enzyme...

The Enzolution(R) SIRT1 Assay System is intended for use with the Transcreener(R) OAADPr SIRT Assay Kits (Parts #3046 and #3047) to measure the enzymatic activity of SIRT1 (NAD-dependent protein deacetylase sirtuin 1). SIRT1 catalyzes transfer of acetyl groups from lysine residues to NAD, yielding the unacetylated...

The Enzolution(R) SIRT1 Assay System is intended for use with the Transcreener(R) OAADPr SIRT Assay Kits (Parts #3046 and #3047) to measure the enzymatic activity of SIRT1 (NAD-dependent protein deacetylase sirtuin 1). SIRT1 catalyzes transfer of acetyl groups from lysine residues to NAD, yielding the unacetylated...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SIRT1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SIRT1. Next,...

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Sirtuin 1 (SIRT1) is a NAD-dependent deacetylase involved in regulation of chromatin organization, metabolic adaptation, oxidative stress signaling, and cellular survival pathways. Phospho-SIRT1...

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Sirtuin 1 (SIRT1) is a NAD-dependent protein deacetylase involved in regulation of metabolic adaptation, chromatin signaling, oxidative stress responses, and cellular survival pathways. Phospho-SIRT1...

Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast Silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...

The Fluorogenic SIRT1 Assay Kit is a complete assay system designed to measure Sirtuin 1 (SIRT1) activity for screening and profiling Applications. It comes in a convenient 96-well format, with all the reagents necessary for 100 fluorescent SIRT1 (Sir2) activity measurements. In addition, the kit includes purified...

Active human Sirtuin 1 , GenBank Accession No. NM_012238), amino acids 193- 741 with N-terminal GST tag, MW= 87.2 kDa, expressed in E. coli expression system.

The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins,...

Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast Sir2 (Silent information regulator 2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...

Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function...