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X-ray repair cross-complementing protein 1 (XRCC1) has been identified as a gene that partially rescues a DNA repair defect and therefore plays a role in efficient repair of single-stranded breaks in DNA damage caused by ionizing radiation. XRCC1 interacts with human polynucleotide kinase, DNA polymerase-beta, and...

X-ray repair cross-complementing protein 1 (XRCC1) has been identified as a gene that partially rescues a DNA repair defect and therefore plays a role in efficient repair of single-stranded breaks in DNA damage caused by ionizing radiation. XRCC1 interacts with human polynucleotide kinase, DNA polymerase-beta, and...

XRCC1 functions in damaged DNA binding and single strand break repair.

X-ray repair cross-complementing protein 1 (XRCC1) has been identified as a gene that partially rescues a DNA repair defect and therefore plays a role in efficient repair of single-stranded breaks in DNA damage caused by ionizing radiation. XRCC1 interacts with human polynucleotide kinase, DNA polymerase-beta, and...

X-ray repair cross-complementing protein 1 (XRCC1) has been identified as a gene that partially rescues a DNA repair defect and therefore plays a role in efficient repair of single-stranded breaks in DNA damage caused by ionizing radiation. XRCC1 interacts with human polynucleotide kinase, DNA polymerase-beta, and...

X-ray repair cross-complementing protein 1 (XRCC1) has been identified as a gene that partially rescues a DNA repair defect and therefore plays a role in efficient repair of single-stranded breaks in DNA damage caused by ionizing radiation. XRCC1 interacts with human polynucleotide kinase, DNA polymerase-beta, and...

X-ray repair cross-complementing protein 1 (XRCC1) has been identified as a gene that partially rescues a DNA repair defect and therefore plays a role in efficient repair of single-stranded breaks in DNA damage caused by ionizing radiation. XRCC1 interacts with human polynucleotide kinase, DNA polymerase-beta, and...

X-ray repair cross-complementing protein 1 (XRCC1) has been identified as a gene that partially rescues a DNA repair defect and therefore plays a role in efficient repair of single-stranded breaks in DNA damage caused by ionizing radiation. XRCC1 interacts with human polynucleotide kinase, DNA polymerase-beta, and...

X-ray repair cross-complementing protein 1 (XRCC1) has been identified as a gene that partially rescues a DNA repair defect and therefore plays a role in efficient repair of single-stranded breaks in DNA damage caused by ionizing radiation. XRCC1 interacts with human polynucleotide kinase, DNA polymerase-beta, and...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....